Literature DB >> 28616830

The Efficacy of Genetic Counseling for Psychiatric Disorders: a Meta-Analysis.

Ramona Moldovan1, Sebastian Pintea2, Jehannine Austin3,4.   

Abstract

Psychiatric illnesses are complex, highly heritable disorders that have substantial implications for both affected individuals and their families. Though genetic testing is currently limited in its clinical usefulness in this area, interest in genetic counseling for psychiatric disorders has a relatively long history and many positive outcomes have been posited. Yet, empirical studies of genetic counseling outcomes have been emerging only more recently. The aim of the current meta-analysis was to analyze the efficacy of genetic counseling and explore potential moderators of its effect. An extensive electronic search was conducted investigating the literature published until July 2016. The initial search resulted in 2367 articles, four of which met the inclusion criteria and were included in the quantitative meta-analysis. Effect size parameters and sample sizes for all variables in each study were included. The efficacy has ben demonstrated both at post-intervention and at follow up, with an overall statistically significant effect size of moderate intensity. Implications of this study are discussed in detail.

Entities:  

Keywords:  Genetic counseling; Meta-analysis; Psychiatric disorders

Mesh:

Year:  2017        PMID: 28616830     DOI: 10.1007/s10897-017-0113-8

Source DB:  PubMed          Journal:  J Genet Couns        ISSN: 1059-7700            Impact factor:   2.537


  28 in total

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Journal:  Br J Psychiatry Suppl       Date:  2001-04

2.  How does recent knowledge on the heredity of schizophrenia affect genetic counseling?

Authors:  George N Papadimitriou; Dimitris G Dikeos
Journal:  Curr Psychiatry Rep       Date:  2003-08       Impact factor: 5.285

3.  A new definition of Genetic Counseling: National Society of Genetic Counselors' Task Force report.

Authors:  Robert Resta; Barbara Bowles Biesecker; Robin L Bennett; Sandra Blum; Susan Estabrooks Hahn; Michelle N Strecker; Janet L Williams
Journal:  J Genet Couns       Date:  2006-04       Impact factor: 2.537

4.  A power primer.

Authors:  J Cohen
Journal:  Psychol Bull       Date:  1992-07       Impact factor: 17.737

5.  Evaluating genetic counseling for family members of individuals with schizophrenia in the molecular age.

Authors:  Gregory Costain; Mary Jane Esplen; Brenda Toner; Kathleen A Hodgkinson; Anne S Bassett
Journal:  Schizophr Bull       Date:  2012-10-27       Impact factor: 9.306

Review 6.  Genetically mediated vulnerability to schizophrenia.

Authors:  C A Prescott; I I Gottesman
Journal:  Psychiatr Clin North Am       Date:  1993-06

Review 7.  The potential impact of genetic counseling for mental illness.

Authors:  J C Austin; W G Honer
Journal:  Clin Genet       Date:  2005-02       Impact factor: 4.438

8.  Family risk and related education and counseling needs: perceptions of adults with bipolar disorder and siblings of adults with bipolar disorder.

Authors:  H L Peay; G W Hooker; L Kassem; B B Biesecker
Journal:  Am J Med Genet A       Date:  2009-03       Impact factor: 2.802

Review 9.  New ethical issues for genetic counseling in common mental disorders.

Authors:  Elliot S Gershon; Ney Alliey-Rodriguez
Journal:  Am J Psychiatry       Date:  2013-09       Impact factor: 18.112

10.  The importance of genetic counseling for individuals with schizophrenia and their relatives: potential clients' opinions and experiences.

Authors:  Vicki L Lyus
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2007-12-05       Impact factor: 3.568

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  11 in total

Review 1.  International Society of Psychiatric Genetics Ethics Committee: Issues facing us.

Authors:  Gabriel Lázaro-Muñoz; Maya Sabatello; Laura Huckins; Holly Peay; Franziska Degenhardt; Bettina Meiser; Todd Lencz; Takahiro Soda; Anna Docherty; David Crepaz-Keay; Jehannine Austin; Roseann E Peterson; Lea K Davis
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2019-05-23       Impact factor: 3.568

2.  Parkinson's Disease: Patients' Knowledge, Attitudes, and Interest in Genetic Counseling.

Authors:  Kristin A Maloney; Dina S Alaeddin; Rainer von Coelln; Shannan Dixon; Lisa M Shulman; Katrina Schrader; Yue Guan
Journal:  J Genet Couns       Date:  2018-03-02       Impact factor: 2.537

3.  An ethical analysis of divergent clinical approaches to the application of genetic testing for autism and schizophrenia.

Authors:  E Morris; M O'Donovan; A Virani; J Austin
Journal:  Hum Genet       Date:  2021-08-28       Impact factor: 4.132

Review 4.  Four Actionable Bottlenecks and Potential Solutions to Translating Psychiatric Genetics Research: An Expert Review.

Authors:  Jessica L Bourdon; Rachel A Davies; Elizabeth C Long
Journal:  Public Health Genomics       Date:  2020-11-04       Impact factor: 2.000

5.  In-vivo design feedback and perceived utility of a genetically-informed smoking risk tool among current smokers in the community.

Authors:  Jessica L Bourdon; Amelia Dorsey; Maia Zalik; Amanda Pietka; Patricia Salyer; Michael J Bray; Laura J Bierut; Alex T Ramsey
Journal:  BMC Med Genomics       Date:  2021-05-26       Impact factor: 3.063

6.  Ethical concerns relating to genetic risk scores for suicide.

Authors:  Anna Docherty; Brent Kious; Teneille Brown; Leslie Francis; Louisa Stark; Brooks Keeshin; Jeffrey Botkin; Emily DiBlasi; Doug Gray; Hilary Coon
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2021-09-01       Impact factor: 3.568

7.  Assessing Stakeholder Perceptions of the Utility of Genetic Information for the Clinical Care of Mental Health Disorders: We Have a Will but Need to See the Way.

Authors:  Jessica L Bourdon; John M Hettema; Elizabeth C Prom-Wormley; Michael A Southam-Gerow
Journal:  Adm Policy Ment Health       Date:  2021-03

8.  The practical utility of genetic screening in school settings.

Authors:  J Shero; W van Dijk; A Edwards; C Schatschneider; E J Solari; S A Hart
Journal:  NPJ Sci Learn       Date:  2021-06-01

Review 9.  Evidence-Based Genetic Counseling for Psychiatric Disorders: A Road Map.

Authors:  Jehannine C Austin
Journal:  Cold Spring Harb Perspect Med       Date:  2020-06-01       Impact factor: 5.159

Review 10.  Updates on Genome-Wide Association Findings in Eating Disorders and Future Application to Precision Medicine.

Authors:  Lauren Breithaupt; Christopher Hubel; Cynthia M Bulik
Journal:  Curr Neuropharmacol       Date:  2018       Impact factor: 7.363

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