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Literature DB >> 28595832

Cycling around Lysine Modifications.

Abstract

Recent studies have revealed the existence of a plethora of previously unknown protein acyl-lysine modifications, affecting the functions of targets involved in diverse cellular processes. A recent study from the Hirschey laboratory has provided new chemical insights into the mechanisms of protein acylation.

Entities: Chemical Disease Gene Species

Keywords: HMGylation; MGcylation; MGylation; SIRT4; non-enzymatic acylation

Mesh：

Substances：
Lysine

Year: 2017 PMID： 28595832 PMCID： PMC5518615 DOI： 10.1016/j.tibs.2017.05.006

Source DB: PubMed Journal: Trends Biochem Sci ISSN： 0968-0004 Impact factor: 13.807

10 in total

1. Acetyl-ed question in mitochondrial biology?

Authors: David B Lombard; Banaja P Dash; Surinder Kumar
Journal: EMBO J Date: 2015-09-14 Impact factor: 11.598

2. The Mammalian Malonyl-CoA Synthetase ACSF3 Is Required for Mitochondrial Protein Malonylation and Metabolic Efficiency.

Authors: Caitlyn E Bowman; Susana Rodriguez; Ebru S Selen Alpergin; Michelle G Acoba; Liang Zhao; Thomas Hartung; Steven M Claypool; Paul A Watkins; Michael J Wolfgang
Journal: Cell Chem Biol Date: 2017-05-04 Impact factor: 8.116

3. Discovering Targets of Non-enzymatic Acylation by Thioester Reactivity Profiling.

Authors: Rhushikesh A Kulkarni; Andrew J Worth; Thomas T Zengeya; Jonathan H Shrimp; Julie M Garlick; Allison M Roberts; David C Montgomery; Carole Sourbier; Benjamin K Gibbs; Clementina Mesaros; Yien Che Tsai; Sudipto Das; King C Chan; Ming Zhou; Thorkell Andresson; Allan M Weissman; W Marston Linehan; Ian A Blair; Nathaniel W Snyder; Jordan L Meier
Journal: Cell Chem Biol Date: 2017-02-02 Impact factor: 8.116

4. A Class of Reactive Acyl-CoA Species Reveals the Non-enzymatic Origins of Protein Acylation.

Authors: Gregory R Wagner; Dhaval P Bhatt; Thomas M O'Connell; J Will Thompson; Laura G Dubois; Donald S Backos; Hao Yang; Grant A Mitchell; Olga R Ilkayeva; Robert D Stevens; Paul A Grimsrud; Matthew D Hirschey
Journal: Cell Metab Date: 2017-04-04 Impact factor: 27.287

5. SIRT4 Is a Lysine Deacylase that Controls Leucine Metabolism and Insulin Secretion.

Authors: Kristin A Anderson; Frank K Huynh; Kelsey Fisher-Wellman; J Darren Stuart; Brett S Peterson; Jonathan D Douros; Gregory R Wagner; J Will Thompson; Andreas S Madsen; Michelle F Green; R Michael Sivley; Olga R Ilkayeva; Robert D Stevens; Donald S Backos; John A Capra; Christian A Olsen; Jonathan E Campbell; Deborah M Muoio; Paul A Grimsrud; Matthew D Hirschey
Journal: Cell Metab Date: 2017-04-04 Impact factor: 27.287

Review 6. Nonenzymatic protein acylation as a carbon stress regulated by sirtuin deacylases.

Authors: Gregory R Wagner; Matthew D Hirschey
Journal: Mol Cell Date: 2014-04-10 Impact factor: 17.970

7. Lysine glutarylation is a protein posttranslational modification regulated by SIRT5.

Authors: Minjia Tan; Chao Peng; Kristin A Anderson; Peter Chhoy; Zhongyu Xie; Lunzhi Dai; Jeongsoon Park; Yue Chen; He Huang; Yi Zhang; Jennifer Ro; Gregory R Wagner; Michelle F Green; Andreas S Madsen; Jessica Schmiesing; Brett S Peterson; Guofeng Xu; Olga R Ilkayeva; Michael J Muehlbauer; Thomas Braulke; Chris Mühlhausen; Donald S Backos; Christian A Olsen; Peter J McGuire; Scott D Pletcher; David B Lombard; Matthew D Hirschey; Yingming Zhao
Journal: Cell Metab Date: 2014-04-01 Impact factor: 27.287

1 in total

Review 1. Functions of the sirtuin deacylase SIRT5 in normal physiology and pathobiology.

Authors: Surinder Kumar; David B Lombard
Journal: Crit Rev Biochem Mol Biol Date: 2018-04-11 Impact factor: 8.250