Literature DB >> 28588762

Baclofen overdose mimicking anoxic encephalopathy: a case report and review of the literature.

John J Miller1.   

Abstract

A patient who has overdosed on baclofen can present with significant neurological symptoms suggestive of a serious brain insult, but with appropriate diagnosis and treatment they often fully recover within 72 h. If the patient had been maintained on chronic baclofen therapy prior to the overdose, one must be watchful for signs of baclofen withdrawal as recovery from the overdose occurs.

Entities:  

Keywords:  baclofen overdose; baclofen withdrawal; serious neurological symptoms

Year:  2017        PMID： 28588762      PMCID： PMC5444597          DOI： 10.1177/2042098617693571

Source DB:  PubMed          Journal:  Ther Adv Drug Saf        ISSN： 2042-0986


  13 in total

1.  Treatment of baclofen overdose by haemodialysis: a pharmacokinetic study.

Authors:  Vin-Cent Wu; Shuei-Liong Lin; Shu-Meng Lin; Cheng-Chung Fang
Journal:  Nephrol Dial Transplant       Date:  2004-12-22       Impact factor: 5.992

Review 2.  EEG changes in intrathecal baclofen overdose: a case report and review of the literature.

Authors:  T Fakhoury; B Abou-Khalil; B Blumenkopf
Journal:  Electroencephalogr Clin Neurophysiol       Date:  1998-11

3.  Baclofen overdose: drug experimentation in a group of adolescents.

Authors:  H E Perry; R O Wright; M W Shannon; A D Woolf
Journal:  Pediatrics       Date:  1998-06       Impact factor: 7.124

4.  Pharmacokinetics in baclofen overdose.

Authors:  P Anderson; H Nohér; C G Swahn
Journal:  J Toxicol Clin Toxicol       Date:  1984-07

5.  Baclofen overdose with cardiac conduction abnormalities: case report and review of the literature.

Authors:  S Nugent; M D Katz; T E Little
Journal:  J Toxicol Clin Toxicol       Date:  1986

6.  Coma mimicking brain death following baclofen overdose.

Authors:  M E Ostermann; B Young; W J Sibbald; M W Nicolle
Journal:  Intensive Care Med       Date:  2000-08       Impact factor: 17.440

7.  Intrathecal baclofen overdose and withdrawal.

Authors:  Kelly W Shirley; Sanjeev Kothare; Joseph H Piatt; Terry A Adirim
Journal:  Pediatr Emerg Care       Date:  2006-04       Impact factor: 1.454

8.  Prolonged severe withdrawal symptoms after acute-on-chronic baclofen overdose.

Authors:  C T Peng; J Ger; C C Yang; W J Tsai; J F Deng; M J Bullard
Journal:  J Toxicol Clin Toxicol       Date:  1998

9.  Physostigmine in the treatment of intrathecal baclofen overdose. Report of three cases.

Authors:  G Müller-Schwefe; R D Penn
Journal:  J Neurosurg       Date:  1989-08       Impact factor: 5.115

10.  Baclofen overdose.

Authors:  D J Lipscomb; T J Meredith
Journal:  Postgrad Med J       Date:  1980-02       Impact factor: 2.401
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  2 in total

1.  Baclofen overdose: A curious case of medical sales representative.

Authors:  Swotantra Gautam; Aakash Neupane; Mandita Chamlagain; Sandip Pokhrel; Durga Neupane; Rochana Acharya; Sagar Panthi
Journal:  Clin Case Rep       Date:  2022-08-09

2.  Low-Dose Baclofen-Induced Encephalopathy in a Healthy Young Adult: Is Baclofen Toxicity Dose-Dependent?

Authors:  Emeka Ibeson; Ifeanyi Nwosu; Thai Donenfeld; Britney Clemen; Ufeh Annabel Ogar; Omosefe E Ogbeifun; Michael Marcelin
Journal:  Cureus       Date:  2021-12-18
  2 in total

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