Literature DB >> 28539489

LIPA Variants in Genome-Wide Association Studies of Coronary Artery Diseases: Loss-of-Function or Gain-of-Function?

Hanrui Zhang1, Muredach P Reilly2.   

Abstract

Entities:  

Keywords:  Editorials; atherosclerosis; cholesteryl esters; coronary artery disease; genetics; macrophage

Mesh：

Substances：

Year:  2017        PMID： 28539489      PMCID： PMC5526101          DOI： 10.1161/ATVBAHA.117.309344

Source DB:  PubMed          Journal:  Arterioscler Thromb Vasc Biol        ISSN： 1079-5642            Impact factor:   8.311


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  25 in total

1.  Functional analysis and transcriptomic profiling of iPSC-derived macrophages and their application in modeling Mendelian disease.

Authors:  Hanrui Zhang; Chenyi Xue; Rhia Shah; Kate Bermingham; Christine C Hinkle; Wenjun Li; Amrith Rodrigues; Jennifer Tabita-Martinez; John S Millar; Marina Cuchel; Evanthia E Pashos; Ying Liu; Ruilan Yan; Wenli Yang; Sager J Gosai; Daniel VanDorn; Stella T Chou; Brian D Gregory; Edward E Morrisey; Mingyao Li; Daniel J Rader; Muredach P Reilly
Journal:  Circ Res       Date:  2015-04-22       Impact factor: 17.367

2.  Genetic Ancestry and Natural Selection Drive Population Differences in Immune Responses to Pathogens.

Authors:  Yohann Nédélec; Joaquín Sanz; Golshid Baharian; Zachary A Szpiech; Alain Pacis; Anne Dumaine; Jean-Christophe Grenier; Andrew Freiman; Aaron J Sams; Steven Hebert; Ariane Pagé Sabourin; Francesca Luca; Ran Blekhman; Ryan D Hernandez; Roger Pique-Regi; Jenny Tung; Vania Yotova; Luis B Barreiro
Journal:  Cell       Date:  2016-10-20       Impact factor: 41.582

Review 3.  From Loci to Biology: Functional Genomics of Genome-Wide Association for Coronary Disease.

Authors:  Sylvia T Nurnberg; Hanrui Zhang; Nicholas J Hand; Robert C Bauer; Danish Saleheen; Muredach P Reilly; Daniel J Rader
Journal:  Circ Res       Date:  2016-02-19       Impact factor: 17.367

4.  Effects of cellular cholesterol loading on macrophage foam cell lysosome acidification.

Authors:  Brian E Cox; Evelyn E Griffin; Jody C Ullery; W Gray Jerome
Journal:  J Lipid Res       Date:  2007-02-16       Impact factor: 5.922

5.  Large-scale association analysis identifies new risk loci for coronary artery disease.

Authors:  Panos Deloukas; Stavroula Kanoni; Christina Willenborg; Martin Farrall; Themistocles L Assimes; John R Thompson; Erik Ingelsson; Danish Saleheen; Jeanette Erdmann; Benjamin A Goldstein; Kathleen Stirrups; Inke R König; Jean-Baptiste Cazier; Asa Johansson; Alistair S Hall; Jong-Young Lee; Cristen J Willer; John C Chambers; Tõnu Esko; Lasse Folkersen; Anuj Goel; Elin Grundberg; Aki S Havulinna; Weang K Ho; Jemma C Hopewell; Niclas Eriksson; Marcus E Kleber; Kati Kristiansson; Per Lundmark; Leo-Pekka Lyytikäinen; Suzanne Rafelt; Dmitry Shungin; Rona J Strawbridge; Gudmar Thorleifsson; Emmi Tikkanen; Natalie Van Zuydam; Benjamin F Voight; Lindsay L Waite; Weihua Zhang; Andreas Ziegler; Devin Absher; David Altshuler; Anthony J Balmforth; Inês Barroso; Peter S Braund; Christof Burgdorf; Simone Claudi-Boehm; David Cox; Maria Dimitriou; Ron Do; Alex S F Doney; NourEddine El Mokhtari; Per Eriksson; Krista Fischer; Pierre Fontanillas; Anders Franco-Cereceda; Bruna Gigante; Leif Groop; Stefan Gustafsson; Jörg Hager; Göran Hallmans; Bok-Ghee Han; Sarah E Hunt; Hyun M Kang; Thomas Illig; Thorsten Kessler; Joshua W Knowles; Genovefa Kolovou; Johanna Kuusisto; Claudia Langenberg; Cordelia Langford; Karin Leander; Marja-Liisa Lokki; Anders Lundmark; Mark I McCarthy; Christa Meisinger; Olle Melander; Evelin Mihailov; Seraya Maouche; Andrew D Morris; Martina Müller-Nurasyid; Kjell Nikus; John F Peden; N William Rayner; Asif Rasheed; Silke Rosinger; Diana Rubin; Moritz P Rumpf; Arne Schäfer; Mohan Sivananthan; Ci Song; Alexandre F R Stewart; Sian-Tsung Tan; Gudmundur Thorgeirsson; C Ellen van der Schoot; Peter J Wagner; George A Wells; Philipp S Wild; Tsun-Po Yang; Philippe Amouyel; Dominique Arveiler; Hanneke Basart; Michael Boehnke; Eric Boerwinkle; Paolo Brambilla; Francois Cambien; Adrienne L Cupples; Ulf de Faire; Abbas Dehghan; Patrick Diemert; Stephen E Epstein; Alun Evans; Marco M Ferrario; Jean Ferrières; Dominique Gauguier; Alan S Go; Alison H Goodall; Villi Gudnason; Stanley L Hazen; Hilma Holm; Carlos Iribarren; Yangsoo Jang; Mika Kähönen; Frank Kee; Hyo-Soo Kim; Norman Klopp; Wolfgang Koenig; Wolfgang Kratzer; Kari Kuulasmaa; Markku Laakso; Reijo Laaksonen; Ji-Young Lee; Lars Lind; Willem H Ouwehand; Sarah Parish; Jeong E Park; Nancy L Pedersen; Annette Peters; Thomas Quertermous; Daniel J Rader; Veikko Salomaa; Eric Schadt; Svati H Shah; Juha Sinisalo; Klaus Stark; Kari Stefansson; David-Alexandre Trégouët; Jarmo Virtamo; Lars Wallentin; Nicholas Wareham; Martina E Zimmermann; Markku S Nieminen; Christian Hengstenberg; Manjinder S Sandhu; Tomi Pastinen; Ann-Christine Syvänen; G Kees Hovingh; George Dedoussis; Paul W Franks; Terho Lehtimäki; Andres Metspalu; Pierre A Zalloua; Agneta Siegbahn; Stefan Schreiber; Samuli Ripatti; Stefan S Blankenberg; Markus Perola; Robert Clarke; Bernhard O Boehm; Christopher O'Donnell; Muredach P Reilly; Winfried März; Rory Collins; Sekar Kathiresan; Anders Hamsten; Jaspal S Kooner; Unnur Thorsteinsdottir; John Danesh; Colin N A Palmer; Robert Roberts; Hugh Watkins; Heribert Schunkert; Nilesh J Samani
Journal:  Nat Genet       Date:  2012-12-02       Impact factor: 38.330

6.  Lysosomal cholesterol accumulation inhibits subsequent hydrolysis of lipoprotein cholesteryl ester.

Authors:  W Gray Jerome; Brian E Cox; Evelyn E Griffin; Jody C Ullery
Journal:  Microsc Microanal       Date:  2008-03-03       Impact factor: 4.127

Review 7.  Lysosomal acid lipase: at the crossroads of normal and atherogenic cholesterol metabolism.

Authors:  Joshua A Dubland; Gordon A Francis
Journal:  Front Cell Dev Biol       Date:  2015-02-02

8.  Survival in infants treated with sebelipase Alfa for lysosomal acid lipase deficiency: an open-label, multicenter, dose-escalation study.

Authors:  Simon A Jones; Sandra Rojas-Caro; Anthony G Quinn; Mark Friedman; Sachin Marulkar; Fatih Ezgu; Osama Zaki; J Jay Gargus; Joanne Hughes; Dominique Plantaz; Roshni Vara; Stephen Eckert; Jean-Baptiste Arnoux; Anais Brassier; Kim-Hanh Le Quan Sang; Vassili Valayannopoulos
Journal:  Orphanet J Rare Dis       Date:  2017-02-08       Impact factor: 4.123

9.  Coronary Artery Disease-Associated LIPA Coding Variant rs1051338 Reduces Lysosomal Acid Lipase Levels and Activity in Lysosomes.

Authors:  Gavin E Morris; Peter S Braund; Jasbir S Moore; Nilesh J Samani; Veryan Codd; Tom R Webb
Journal:  Arterioscler Thromb Vasc Biol       Date:  2017-03-09       Impact factor: 8.311

10.  Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages.

Authors:  Stanley Ching-Cheng Huang; Bart Everts; Yulia Ivanova; David O'Sullivan; Marcia Nascimento; Amber M Smith; Wandy Beatty; Latisha Love-Gregory; Wing Y Lam; Christina M O'Neill; Cong Yan; Hong Du; Nada A Abumrad; Joseph F Urban; Maxim N Artyomov; Erika L Pearce; Edward J Pearce
Journal:  Nat Immunol       Date:  2014-08-03       Impact factor: 25.606
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  7 in total

1.  Functional Characterization of LIPA (Lysosomal Acid Lipase) Variants Associated With Coronary Artery Disease.

Authors:  Trent D Evans; Xiangyu Zhang; Reece E Clark; Arturo Alisio; Eric Song; Hanrui Zhang; Muredach P Reilly; Nathan O Stitziel; Babak Razani
Journal:  Arterioscler Thromb Vasc Biol       Date:  2019-10-24       Impact factor: 8.311

Review 2.  HDL and Reverse Cholesterol Transport.

Authors:  Mireille Ouimet; Tessa J Barrett; Edward A Fisher
Journal:  Circ Res       Date:  2019-05-10       Impact factor: 17.367

3.  Functional Genomics and CRISPR Applied to Cardiovascular Research and Medicine.

Authors:  Fang Li; Jianting Shi; Hong S Lu; Hanrui Zhang
Journal:  Arterioscler Thromb Vasc Biol       Date:  2019-08-21       Impact factor: 8.311

Review 4.  Lysosomal Acid Lipase in Lipid Metabolism and Beyond.

Authors:  Fang Li; Hanrui Zhang
Journal:  Arterioscler Thromb Vasc Biol       Date:  2019-05       Impact factor: 8.311

Review 5.  Lysosomal acid lipase and lipid metabolism: new mechanisms, new questions, and new therapies.

Authors:  Hanrui Zhang
Journal:  Curr Opin Lipidol       Date:  2018-06       Impact factor: 4.776

6.  Genetic and Epigenetic Fine Mapping of Complex Trait Associated Loci in the Human Liver.

Authors:  Minal Çalışkan; Elisabetta Manduchi; H Shanker Rao; Julian A Segert; Marcia Holsbach Beltrame; Marco Trizzino; YoSon Park; Samuel W Baker; Alessandra Chesi; Matthew E Johnson; Kenyaita M Hodge; Michelle E Leonard; Baoli Loza; Dong Xin; Andrea M Berrido; Nicholas J Hand; Robert C Bauer; Andrew D Wells; Kim M Olthoff; Abraham Shaked; Daniel J Rader; Struan F A Grant; Christopher D Brown
Journal:  Am J Hum Genet       Date:  2019-06-13       Impact factor: 11.025

Review 7.  Lysosomal acid lipase deficiency: A rare inherited dyslipidemia but potential ubiquitous factor in the development of atherosclerosis and fatty liver disease.

Authors:  Katrina J Besler; Valentin Blanchard; Gordon A Francis
Journal:  Front Genet       Date:  2022-09-20       Impact factor: 4.772
  7 in total

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