Literature DB >> 28539347

Valproic Acid for a Treatment of Retinitis Pigmentosa: Reasons for Optimism and Caution.

Levi Todd1, Christopher Zelinka2.   

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Year:  2017        PMID: 28539347      PMCID: PMC5456104          DOI: 10.1523/JNEUROSCI.0774-17.2017

Source DB:  PubMed          Journal:  J Neurosci        ISSN: 0270-6474            Impact factor:   6.167


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  22 in total

1.  Lack of scientific rationale for use of valproic acid for retinitis pigmentosa.

Authors:  Michael A Sandberg; Bernard Rosner; Carol Weigel-DiFranco; Eliot L Berson
Journal:  Br J Ophthalmol       Date:  2010-12-03       Impact factor: 4.638

2.  Therapeutic potential of valproic acid for retinitis pigmentosa.

Authors:  C M Clemson; R Tzekov; M Krebs; J M Checchi; C Bigelow; S Kaushal
Journal:  Br J Ophthalmol       Date:  2010-07-20       Impact factor: 4.638

3.  The role of rhodopsin glycosylation in protein folding, trafficking, and light-sensitive retinal degeneration.

Authors:  Beatrice M Tam; Orson L Moritz
Journal:  J Neurosci       Date:  2009-12-02       Impact factor: 6.167

4.  Characterization of rhodopsin P23H-induced retinal degeneration in a Xenopus laevis model of retinitis pigmentosa.

Authors:  Beatrice M Tam; Orson L Moritz
Journal:  Invest Ophthalmol Vis Sci       Date:  2006-08       Impact factor: 4.799

5.  Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen.

Authors:  C J Phiel; F Zhang; E Y Huang; M G Guenther; M A Lazar; P S Klein
Journal:  J Biol Chem       Date:  2001-07-25       Impact factor: 5.157

6.  Opposing Effects of Valproic Acid Treatment Mediated by Histone Deacetylase Inhibitor Activity in Four Transgenic X. laevis Models of Retinitis Pigmentosa.

Authors:  Ruanne Y J Vent-Schmidt; Runxia H Wen; Zusheng Zong; Colette N Chiu; Beatrice M Tam; Christopher G May; Orson L Moritz
Journal:  J Neurosci       Date:  2017-01-25       Impact factor: 6.167

7.  Photoactivation-induced instability of rhodopsin mutants T4K and T17M in rod outer segments underlies retinal degeneration in X. laevis transgenic models of retinitis pigmentosa.

Authors:  Beatrice M Tam; Syed M Noorwez; Shalesh Kaushal; Masahiro Kono; Orson L Moritz
Journal:  J Neurosci       Date:  2014-10-01       Impact factor: 6.167

Review 8.  Multiple roles of HDAC inhibition in neurodegenerative conditions.

Authors:  De-Maw Chuang; Yan Leng; Zoya Marinova; Hyeon-Ju Kim; Chi-Tso Chiu
Journal:  Trends Neurosci       Date:  2009-09-21       Impact factor: 13.837

9.  Requirement of histone deacetylase activity for the expression of critical photoreceptor genes.

Authors:  Bo Chen; Constance L Cepko
Journal:  BMC Dev Biol       Date:  2007-06-29       Impact factor: 1.978

Review 10.  Genes and mutations causing retinitis pigmentosa.

Authors:  S P Daiger; L S Sullivan; S J Bowne
Journal:  Clin Genet       Date:  2013-06-19       Impact factor: 4.438

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  4 in total

1.  SAHA is neuroprotective in in vitro and in situ models of retinitis pigmentosa.

Authors:  Nathan R Perron; Cécile Nasarre; Mausumi Bandyopadhyay; Craig C Beeson; Baerbel Rohrer
Journal:  Mol Vis       Date:  2021-04-02       Impact factor: 2.367

2.  Large-scale phenotypic drug screen identifies neuroprotectants in zebrafish and mouse models of retinitis pigmentosa.

Authors:  Liyun Zhang; Conan Chen; Jie Fu; Brendan Lilley; Cynthia Berlinicke; Baranda Hansen; Ding Ding; Guohua Wang; Tao Wang; Daniel Shou; Ying Ye; Timothy Mulligan; Kevin Emmerich; Meera T Saxena; Kelsi R Hall; Abigail V Sharrock; Carlene Brandon; Hyejin Park; Tae-In Kam; Valina L Dawson; Ted M Dawson; Joong Sup Shim; Justin Hanes; Hongkai Ji; Jun O Liu; Jiang Qian; David F Ackerley; Baerbel Rohrer; Donald J Zack; Jeff S Mumm
Journal:  Elife       Date:  2021-06-29       Impact factor: 8.140

3.  Inhibition of Epigenetic Modifiers LSD1 and HDAC1 Blocks Rod Photoreceptor Death in Mouse Models of Retinitis Pigmentosa.

Authors:  Evgenya Y Popova; Yuka Imamura Kawasawa; Samuel Shao-Min Zhang; Colin J Barnstable
Journal:  J Neurosci       Date:  2021-06-30       Impact factor: 6.167

Review 4.  Recent advances in genetically modified animal models of glaucoma and their roles in drug repositioning.

Authors:  Chikako Harada; Atsuko Kimura; Xiaoli Guo; Kazuhiko Namekata; Takayuki Harada
Journal:  Br J Ophthalmol       Date:  2018-10-26       Impact factor: 4.638

  4 in total

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