Literature DB >> 28529981

Caenorhabditis elegans: An important tool for dissecting microRNA functions.

Ziwen Zhu1, Duo Zhang1, Heedoo Lee1, Yang Jin1.   

Abstract

Caenorhabditis elegans (C. elegans), a member of the phylum Nematoda, carries the evolutionarily conserved genes comparing to mammals. Due to its short lifespan and completely sequenced genome, C. elegans becomes a potentially powerful model for mechanistic studies in human diseases. In this mini review, we will outline the current understandings on C. elegans as a model organism for microRNA (miRNA)-related research in the pathogenesis of human diseases.

Entities:  

Keywords:  Caenorhabditis elegans; function; microRNA

Year:  2016        PMID： 28529981      PMCID： PMC5438092          DOI： 10.15761/BGG.1000106

Source DB:  PubMed          Journal:  Biomed Genet Genom        ISSN： 2398-5399


  37 in total

1.  Toward a physical map of the genome of the nematode Caenorhabditis elegans.

Authors:  A Coulson; J Sulston; S Brenner; J Karn
Journal:  Proc Natl Acad Sci U S A       Date:  1986-10       Impact factor: 11.205

2.  Effect of life history on microRNA expression during C. elegans development.

Authors:  Xantha Karp; Molly Hammell; Maria C Ow; Victor Ambros
Journal:  RNA       Date:  2011-02-22       Impact factor: 4.942

3.  Basic Caenorhabditis elegans methods: synchronization and observation.

Authors:  Montserrat Porta-de-la-Riva; Laura Fontrodona; Alberto Villanueva; Julián Cerón
Journal:  J Vis Exp       Date:  2012-06-10       Impact factor: 1.355

4.  Caenorhabditis elegans body mechanics are regulated by body wall muscle tone.

Authors:  Bryan C Petzold; Sung-Jin Park; Pierre Ponce; Clifton Roozeboom; Chloé Powell; Miriam B Goodman; Beth L Pruitt
Journal:  Biophys J       Date:  2011-04-20       Impact factor: 4.033

5.  An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans.

Authors:  N C Lau; L P Lim; E G Weinstein; D P Bartel
Journal:  Science       Date:  2001-10-26       Impact factor: 47.728

6.  An extensive class of small RNAs in Caenorhabditis elegans.

Authors:  R C Lee; V Ambros
Journal:  Science       Date:  2001-10-26       Impact factor: 47.728

Review 7.  Genome sequence of the nematode C. elegans: a platform for investigating biology.

Authors: 
Journal:  Science       Date:  1998-12-11       Impact factor: 47.728

8.  Lattice light-sheet microscopy: imaging molecules to embryos at high spatiotemporal resolution.

Authors:  Bi-Chang Chen; Wesley R Legant; Kai Wang; Lin Shao; Daniel E Milkie; Michael W Davidson; Chris Janetopoulos; Xufeng S Wu; John A Hammer; Zhe Liu; Brian P English; Yuko Mimori-Kiyosue; Daniel P Romero; Alex T Ritter; Jennifer Lippincott-Schwartz; Lillian Fritz-Laylin; R Dyche Mullins; Diana M Mitchell; Joshua N Bembenek; Anne-Cecile Reymann; Ralph Böhme; Stephan W Grill; Jennifer T Wang; Geraldine Seydoux; U Serdar Tulu; Daniel P Kiehart; Eric Betzig
Journal:  Science       Date:  2014-10-23       Impact factor: 47.728

9.  Deletion of microRNA-80 activates dietary restriction to extend C. elegans healthspan and lifespan.

Authors:  Mehul Vora; Mitalie Shah; Silvana Ostafi; Brian Onken; Jian Xue; Julie Zhouli Ni; Sam Gu; Monica Driscoll
Journal:  PLoS Genet       Date:  2013-08-29       Impact factor: 5.917

10.  The C. elegans microRNA mir-71 acts in neurons to promote germline-mediated longevity through regulation of DAF-16/FOXO.

Authors:  Konstantinos Boulias; H Robert Horvitz
Journal:  Cell Metab       Date:  2012-04-04       Impact factor: 27.287
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  1 in total

Review 1.  The Nematode Caenorhabditis elegans as a Model Organism to Study Metabolic Effects of ω-3 Polyunsaturated Fatty Acids in Obesity.

Authors:  Amal Bouyanfif; Shasika Jayarathne; Iurii Koboziev; Naima Moustaid-Moussa
Journal:  Adv Nutr       Date:  2019-01-01       Impact factor: 8.701
  1 in total

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