| Literature DB >> 28501083 |
Chao Zhang1, Sarah Ellen Powell2, Doron Betel1, Manish A Shah3.
Abstract
Gastric malignancies are a leading cause of cancer-related death worldwide. At least 2 microbial species are currently linked to carcinogenesis and the development of cancer within the human stomach. These include the bacterium Helicobacter pylori and the Epstein-Barr virus. In recent years, there has been increasing evidence that within the human gastrointestinal tract it is not only pathogenic microbes that impact human health but also the corresponding autochthonous microbial communities. This article reviews the gastrointestinal microbiome as it relates primarily to mechanisms of disease and carcinogenesis within the upper gastrointestinal tract.Entities:
Keywords: EBV; Gastric cancer; Gastric microbiome; Helicobacter pylori; Microbial identification
Mesh：
Year: 2017 PMID： 28501083 DOI： 10.1016/j.hoc.2017.01.002
Source DB: PubMed Journal: Hematol Oncol Clin North Am ISSN： 0889-8588 Impact factor: 3.722