| Literature DB >> 28493437 |
Gangjun Liu1, Jianlong Yang1, Jie Wang1, Yan Li1, Pengxiao Zang1, Yali Jia1, David Huang1.
Abstract
We developed a high-speed, swept source OCT system for widefield OCT angiography (OCTA) imaging. The system has an extended axial imaging range of 6.6 mm. An electrical lens is used for fast, automatic focusing. The recently developed split-spectrum amplitude and phase-gradient angiography allow high-resolution OCTA imaging with only two B-scan repetitions. An improved post-processing algorithm effectively removed trigger jitter artifacts and reduced noise in the flow signal. We demonstrated high contrast 3 mm×3 mm OCTA image with 400×400 pixels acquired in 3 seconds and high-definition 8 mm×6 mm and 12 mm×6 mm OCTA images with 850×400 pixels obtained in 4 seconds. A widefield 8 mm×11 mm OCTA image is produced by montaging two 8 mm×6 mm scans. An ultra-widefield (with a maximum of 22 mm along both vertical and horizontal directions) capillary-resolution OCTA image is obtained by montaging six 12 mm×6 mm scans.Entities:
Keywords: Optical coherence tomography; optical coherence tomography angiography; widefield imaging.
Mesh:
Year: 2017 PMID: 28493437 PMCID: PMC6145849 DOI: 10.1002/jbio.201600325
Source DB: PubMed Journal: J Biophotonics ISSN: 1864-063X Impact factor: 3.207