Literature DB >> 28486104

IDH Mutation, Competitive Inhibition of FTO, and RNA Methylation.

Sara M Elkashef1, An-Ping Lin1, Jamie Myers1, Heinz Sill2, Daifeng Jiang1, Patricia L M Dahia3, Ricardo C T Aguiar4.   

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Year:  2017        PMID： 28486104      PMCID： PMC5506849          DOI： 10.1016/j.ccell.2017.04.001

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


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  5 in total

1.  FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N6-Methyladenosine RNA Demethylase.

Authors:  Zejuan Li; Hengyou Weng; Rui Su; Xiaocheng Weng; Zhixiang Zuo; Chenying Li; Huilin Huang; Sigrid Nachtergaele; Lei Dong; Chao Hu; Xi Qin; Lichun Tang; Yungui Wang; Gia-Ming Hong; Hao Huang; Xiao Wang; Ping Chen; Sandeep Gurbuxani; Stephen Arnovitz; Yuanyuan Li; Shenglai Li; Jennifer Strong; Mary Beth Neilly; Richard A Larson; Xi Jiang; Pumin Zhang; Jie Jin; Chuan He; Jianjun Chen
Journal:  Cancer Cell       Date:  2016-12-22       Impact factor: 31.743

Review 2.  The AlkB Family of Fe(II)/α-Ketoglutarate-dependent Dioxygenases: Repairing Nucleic Acid Alkylation Damage and Beyond.

Authors:  Bogdan I Fedeles; Vipender Singh; James C Delaney; Deyu Li; John M Essigmann
Journal:  J Biol Chem       Date:  2015-07-07       Impact factor: 5.157

Review 3.  Mutant IDH: a targetable driver of leukemic phenotypes linking metabolism, epigenetics and transcriptional regulation.

Authors:  Francine E Garrett-Bakelman; Ari M Melnick
Journal:  Epigenomics       Date:  2016-07-19       Impact factor: 4.357

Review 4.  Oncogenic isocitrate dehydrogenase mutations: mechanisms, models, and clinical opportunities.

Authors:  Rob A Cairns; Tak W Mak
Journal:  Cancer Discov       Date:  2013-06-24       Impact factor: 38.272

5.  D2HGDH regulates alpha-ketoglutarate levels and dioxygenase function by modulating IDH2.

Authors:  An-Ping Lin; Saman Abbas; Sang-Woo Kim; Manoela Ortega; Hakim Bouamar; Yissela Escobedo; Prakash Varadarajan; Yuejuan Qin; Jessica Sudderth; Eduard Schulz; Alexander Deutsch; Sumitra Mohan; Peter Ulz; Peter Neumeister; Dinesh Rakheja; Xiaoli Gao; Andrew Hinck; Susan T Weintraub; Ralph J DeBerardinis; Heinz Sill; Patricia L M Dahia; Ricardo C T Aguiar
Journal:  Nat Commun       Date:  2015-07-16       Impact factor: 17.694
  5 in total
  29 in total

1.  MYC Regulation of D2HGDH and L2HGDH Influences the Epigenome and Epitranscriptome.

Authors:  ZhiJun Qiu; An-Ping Lin; Shoulei Jiang; Sara M Elkashef; Jamie Myers; Subramanya Srikantan; Binu Sasi; John Z Cao; Lucy A Godley; Dinesh Rakheja; Yingli Lyu; Siyuan Zheng; Muniswamy Madesh; Yuzuru Shiio; Patricia L M Dahia; Ricardo C T Aguiar
Journal:  Cell Chem Biol       Date:  2020-02-25       Impact factor: 8.116

Review 2.  Role of RNA modifications in cancer.

Authors:  Isaia Barbieri; Tony Kouzarides
Journal:  Nat Rev Cancer       Date:  2020-04-16       Impact factor: 60.716

3.  Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia.

Authors:  Lucille Stuani; Marie Sabatier; Estelle Saland; Guillaume Cognet; Nathalie Poupin; Claudie Bosc; Florence A Castelli; Lara Gales; Evgenia Turtoi; Camille Montersino; Thomas Farge; Emeline Boet; Nicolas Broin; Clément Larrue; Natalia Baran; Madi Y Cissé; Marc Conti; Sylvain Loric; Tony Kaoma; Alexis Hucteau; Aliki Zavoriti; Ambrine Sahal; Pierre-Luc Mouchel; Mathilde Gotanègre; Cédric Cassan; Laurent Fernando; Feng Wang; Mohsen Hosseini; Emeline Chu-Van; Laurent Le Cam; Martin Carroll; Mary A Selak; Norbert Vey; Rémy Castellano; François Fenaille; Andrei Turtoi; Guillaume Cazals; Pierre Bories; Yves Gibon; Brandon Nicolay; Sébastien Ronseaux; Joseph R Marszalek; Koichi Takahashi; Courtney D DiNardo; Marina Konopleva; Véra Pancaldi; Yves Collette; Floriant Bellvert; Fabien Jourdan; Laetitia K Linares; Christian Récher; Jean-Charles Portais; Jean-Emmanuel Sarry
Journal:  J Exp Med       Date:  2021-05-03       Impact factor: 14.307

4.  FTO Regulates Apoptosis in CPB2-Treated IPEC-J2 Cells by Targeting Caspase 3 Apoptotic Protein.

Authors:  Jiaojiao Yang; Juanli Zhang; Xiaoli Gao; Ruirui Luo; Kaihui Xie; Wei Wang; Jie Li; Qiaoli Yang; Xiaoyu Huang; Zunqiang Yan; Pengfei Wang; Shuangbao Gun
Journal:  Animals (Basel)       Date:  2022-06-26       Impact factor: 3.231

Review 5.  Epitranscriptomics in Hematopoiesis and Hematologic Malignancies.

Authors:  Margalida Rosselló-Tortella; Gerardo Ferrer; Manel Esteller
Journal:  Blood Cancer Discov       Date:  2020-06-22

6.  Synergistic Targeting of the Regulatory and Catalytic Subunits of PI3Kδ in Mature B-cell Malignancies.

Authors:  Jeffrey D Cooney; An-Ping Lin; Daifeng Jiang; Long Wang; Avvaru N Suhasini; Jamie Myers; ZhiJun Qiu; Albert Wölfler; Heinz Sill; Ricardo C T Aguiar
Journal:  Clin Cancer Res       Date:  2017-12-15       Impact factor: 12.531

7.  Generation and characterization of the Eµ-Irf8 mouse model.

Authors:  Zhijun Qiu; Kenneth N Holder; An-Ping Lin; Jamie Myers; Shoulei Jiang; Karla M Gorena; Marsha C Kinney; Ricardo C T Aguiar
Journal:  Cancer Genet       Date:  2020-06-03

Review 8.  RNA Regulators in Leukemia and Lymphoma.

Authors:  Camila Prieto; Michael G Kharas
Journal:  Cold Spring Harb Perspect Med       Date:  2020-05-01       Impact factor: 6.915

Review 9.  Epitranscriptomic influences on development and disease.

Authors:  Phillip J Hsu; Hailing Shi; Chuan He
Journal:  Genome Biol       Date:  2017-10-23       Impact factor: 13.583

10.  R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling.

Authors:  Rui Su; Lei Dong; Chenying Li; Sigrid Nachtergaele; Mark Wunderlich; Ying Qing; Xiaolan Deng; Yungui Wang; Xiaocheng Weng; Chao Hu; Mengxia Yu; Jennifer Skibbe; Qing Dai; Dongling Zou; Tong Wu; Kangkang Yu; Hengyou Weng; Huilin Huang; Kyle Ferchen; Xi Qin; Bin Zhang; Jun Qi; Atsuo T Sasaki; David R Plas; James E Bradner; Minjie Wei; Guido Marcucci; Xi Jiang; James C Mulloy; Jie Jin; Chuan He; Jianjun Chen
Journal:  Cell       Date:  2017-12-14       Impact factor: 66.850
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