Literature DB >> 31615866

RNA Regulators in Leukemia and Lymphoma.

Camila Prieto1, Michael G Kharas1.   

Abstract

Posttranscriptional regulation of mRNA is a powerful and tightly controlled process in which cells command the integrity, diversity, and abundance of their protein products. RNA-binding proteins (RBPs) are the principal players that control many intermediary steps of posttranscriptional regulation. Recent advances in this field have discovered the importance of RBPs in hematological diseases. Herein we will review a number of RBPs that have been determined to play critical functions in leukemia and lymphoma. Furthermore, we will discuss the potential therapeutic strategies that are currently being studied to specifically target RBPs in these diseases.
Copyright © 2020 Cold Spring Harbor Laboratory Press; all rights reserved.

Entities:  

Mesh：

Substances：

Year:  2020        PMID： 31615866      PMCID： PMC7197419          DOI： 10.1101/cshperspect.a034967

Source DB:  PubMed          Journal:  Cold Spring Harb Perspect Med        ISSN： 2157-1422            Impact factor:   6.915


  185 in total

Review 1.  The role of the oncofetal IGF2 mRNA-binding protein 3 (IGF2BP3) in cancer.

Authors:  Marcell Lederer; Nadine Bley; Christian Schleifer; Stefan Hüttelmaier
Journal:  Semin Cancer Biol       Date:  2014-07-25       Impact factor: 15.707

2.  A MAPK/HNRPK pathway controls BCR/ABL oncogenic potential by regulating MYC mRNA translation.

Authors:  Mario Notari; Paolo Neviani; Ramasamy Santhanam; Bradley W Blaser; Ji-Suk Chang; Annamaria Galietta; Anne E Willis; Denis C Roy; Michael A Caligiuri; Guido Marcucci; Danilo Perrotti
Journal:  Blood       Date:  2005-11-17       Impact factor: 22.113

3.  Transcriptome-wide analysis of regulatory interactions of the RNA-binding protein HuR.

Authors:  Svetlana Lebedeva; Marvin Jens; Kathrin Theil; Björn Schwanhäusser; Matthias Selbach; Markus Landthaler; Nikolaus Rajewsky
Journal:  Mol Cell       Date:  2011-06-30       Impact factor: 17.970

4.  Musashi regulates the temporal order of mRNA translation during Xenopus oocyte maturation.

Authors:  Amanda Charlesworth; Anna Wilczynska; Prajitha Thampi; Linda L Cox; Angus M MacNicol
Journal:  EMBO J       Date:  2006-06-08       Impact factor: 11.598

5.  Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells.

Authors:  Omer H Yilmaz; Riccardo Valdez; Brian K Theisen; Wei Guo; David O Ferguson; Hong Wu; Sean J Morrison
Journal:  Nature       Date:  2006-04-05       Impact factor: 49.962

Review 6.  The let-7 family of microRNAs.

Authors:  Sarah Roush; Frank J Slack
Journal:  Trends Cell Biol       Date:  2008-09-04       Impact factor: 20.808

7.  Arginine/serine-rich domains of SR proteins can function as activators of pre-mRNA splicing.

Authors:  B R Graveley; T Maniatis
Journal:  Mol Cell       Date:  1998-04       Impact factor: 17.970

8.  Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia.

Authors:  Gerard Minuesa; Steven K Albanese; Wei Xie; Yaniv Kazansky; Daniel Worroll; Arthur Chow; Alexandra Schurer; Sun-Mi Park; Christina Z Rotsides; James Taggart; Andrea Rizzi; Levi N Naden; Timothy Chou; Saroj Gourkanti; Daniel Cappel; Maria C Passarelli; Lauren Fairchild; Carolina Adura; J Fraser Glickman; Jessica Schulman; Christopher Famulare; Minal Patel; Joseph K Eibl; Gregory M Ross; Shibani Bhattacharya; Derek S Tan; Christina S Leslie; Thijs Beuming; Dinshaw J Patel; Yehuda Goldgur; John D Chodera; Michael G Kharas
Journal:  Nat Commun       Date:  2019-06-19       Impact factor: 14.919

9.  Lin28 promotes transformation and is associated with advanced human malignancies.

Authors:  Srinivas R Viswanathan; John T Powers; William Einhorn; Yujin Hoshida; Tony L Ng; Sara Toffanin; Maureen O'Sullivan; Jun Lu; Letha A Phillips; Victoria L Lockhart; Samar P Shah; Pradeep S Tanwar; Craig H Mermel; Rameen Beroukhim; Mohammad Azam; Jose Teixeira; Matthew Meyerson; Timothy P Hughes; Josep M Llovet; Jerald Radich; Charles G Mullighan; Todd R Golub; Poul H Sorensen; George Q Daley
Journal:  Nat Genet       Date:  2009-05-31       Impact factor: 38.330

Review 10.  N6-methyladenosine links RNA metabolism to cancer progression.

Authors:  Dongjun Dai; Hanying Wang; Liyuan Zhu; Hongchuan Jin; Xian Wang
Journal:  Cell Death Dis       Date:  2018-01-26       Impact factor: 8.469
View more
  6 in total

Review 1.  RNA-binding proteins of COSMIC importance in cancer.

Authors:  Peter S Choi; Andrei Thomas-Tikhonenko
Journal:  J Clin Invest       Date:  2021-09-15       Impact factor: 19.456

2.  Transcriptional control of CBX5 by the RNA binding proteins RBMX and RBMXL1 maintains chromatin state in myeloid leukemia.

Authors:  Camila Prieto; Diu T T Nguyen; Zhaoqi Liu; Justin Wheat; Alexendar Perez; Saroj Gourkanti; Timothy Chou; Ersilia Barin; Anthony Velleca; Thomas Rohwetter; Arthur Chow; James Taggart; Angela M Savino; Katerina Hoskova; Meera Dhodapkar; Alexandra Schurer; Trevor S Barlowe; Ly P Vu; Christina Leslie; Ulrich Steidl; Raul Rabadan; Michael G Kharas
Journal:  Nat Cancer       Date:  2021-07-05

Review 3.  Preleukemic and leukemic evolution at the stem cell level.

Authors:  Jacob Stauber; John M Greally; Ulrich Steidl
Journal:  Blood       Date:  2021-02-25       Impact factor: 22.113

Review 4.  The role of mRNA in the development, diagnosis, treatment and prognosis of neural tumors.

Authors:  Yiyang Zheng; Yanyan Luo; Xixi Chen; Huiting Li; Baojun Huang; Baofeng Zhou; Liqing Zhu; Xianhui Kang; Wujun Geng
Journal:  Mol Cancer       Date:  2021-03-05       Impact factor: 27.401

Review 5.  RNA-Binding Proteins in Acute Leukemias.

Authors:  Konstantin Schuschel; Matthias Helwig; Stefan Hüttelmaier; Dirk Heckl; Jan-Henning Klusmann; Jessica I Hoell
Journal:  Int J Mol Sci       Date:  2020-05-12       Impact factor: 5.923

Review 6.  The Role of RNA-Binding Proteins in Hematological Malignancies.

Authors:  Pedro Aguilar-Garrido; Álvaro Otero-Sobrino; Miguel Ángel Navarro-Aguadero; María Velasco-Estévez; Miguel Gallardo
Journal:  Int J Mol Sci       Date:  2022-08-23       Impact factor: 6.208
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.