Literature DB >> 28480206

Cell secretome based drug substances in regenerative medicine: when regulatory affairs meet basic science.

Lucian Beer1,2, Michael Mildner3, Hendrik Jan Ankersmit2,4,5.   

Abstract

Year:  2017        PMID： 28480206      PMCID： PMC5401661          DOI： 10.21037/atm.2017.03.50

Source DB:  PubMed          Journal:  Ann Transl Med        ISSN： 2305-5839


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  18 in total

1.  Paracrine action accounts for marked protection of ischemic heart by Akt-modified mesenchymal stem cells.

Authors:  Massimiliano Gnecchi; Huamei He; Olin D Liang; Luis G Melo; Fulvio Morello; Hui Mu; Nicolas Noiseux; Lunan Zhang; Richard E Pratt; Joanne S Ingwall; Victor J Dzau
Journal:  Nat Med       Date:  2005-04       Impact factor: 53.440

2.  Mesenchymal-stem-cell-derived exosomes accelerate skeletal muscle regeneration.

Authors:  Yoshihiro Nakamura; Shigeru Miyaki; Hiroyuki Ishitobi; Sho Matsuyama; Tomoyuki Nakasa; Naosuke Kamei; Takayuki Akimoto; Yukihito Higashi; Mitsuo Ochi
Journal:  FEBS Lett       Date:  2015-04-08       Impact factor: 4.124

Review 3.  Exosomes: vehicles of intercellular signaling, biomarkers, and vectors of cell therapy.

Authors:  Stella Kourembanas
Journal:  Annu Rev Physiol       Date:  2014-09-25       Impact factor: 19.318

4.  Myeloid-derived growth factor (C19orf10) mediates cardiac repair following myocardial infarction.

Authors:  Mortimer Korf-Klingebiel; Marc R Reboll; Stefanie Klede; Torben Brod; Andreas Pich; Felix Polten; L Christian Napp; Johann Bauersachs; Arnold Ganser; Eva Brinkmann; Ines Reimann; Tibor Kempf; Hans W Niessen; Jacques Mizrahi; Hans-Joachim Schönfeld; Antonio Iglesias; Maria Bobadilla; Yong Wang; Kai C Wollert
Journal:  Nat Med       Date:  2015-01-12       Impact factor: 53.440

5.  Dynamics of Cell Generation and Turnover in the Human Heart.

Authors:  Olaf Bergmann; Sofia Zdunek; Anastasia Felker; Mehran Salehpour; Kanar Alkass; Samuel Bernard; Staffan L Sjostrom; Mirosława Szewczykowska; Teresa Jackowska; Cris Dos Remedios; Torsten Malm; Michaela Andrä; Ramadan Jashari; Jens R Nyengaard; Göran Possnert; Stefan Jovinge; Henrik Druid; Jonas Frisén
Journal:  Cell       Date:  2015-06-11       Impact factor: 41.582

6.  Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.

Authors:  Hadi Valadi; Karin Ekström; Apostolos Bossios; Margareta Sjöstrand; James J Lee; Jan O Lötvall
Journal:  Nat Cell Biol       Date:  2007-05-07       Impact factor: 28.824

7.  Intravenous and intramyocardial injection of apoptotic white blood cell suspensions prevents ventricular remodelling by increasing elastin expression in cardiac scar tissue after myocardial infarction.

Authors:  Michael Lichtenauer; Michael Mildner; Andrea Baumgartner; Matthias Hasun; Gregor Werba; Lucian Beer; Patrick Altmann; Georg Roth; Mariann Gyöngyösi; Bruno Karl Podesser; Hendrik Jan Ankersmit
Journal:  Basic Res Cardiol       Date:  2011-03-17       Impact factor: 17.165

8.  Secretome of apoptotic peripheral blood cells (APOSEC) confers cytoprotection to cardiomyocytes and inhibits tissue remodelling after acute myocardial infarction: a preclinical study.

Authors:  Michael Lichtenauer; Michael Mildner; Konrad Hoetzenecker; Matthias Zimmermann; Bruno Karl Podesser; Wolfgang Sipos; Ervin Berényi; Martin Dworschak; Erwin Tschachler; Mariann Gyöngyösi; Hendrik Jan Ankersmit
Journal:  Basic Res Cardiol       Date:  2011-09-28       Impact factor: 17.165

Review 9.  Extracellular vesicles: potential roles in regenerative medicine.

Authors:  Olivier G De Jong; Bas W M Van Balkom; Raymond M Schiffelers; Carlijn V C Bouten; Marianne C Verhaar
Journal:  Front Immunol       Date:  2014-12-03       Impact factor: 7.561

10.  Analysis of the Secretome of Apoptotic Peripheral Blood Mononuclear Cells: Impact of Released Proteins and Exosomes for Tissue Regeneration.

Authors:  Lucian Beer; Matthias Zimmermann; Andreas Mitterbauer; Adolf Ellinger; Florian Gruber; Marie-Sophie Narzt; Maria Zellner; Mariann Gyöngyösi; Sibylle Madlener; Elisabeth Simader; Christian Gabriel; Michael Mildner; Hendrik Jan Ankersmit
Journal:  Sci Rep       Date:  2015-11-16       Impact factor: 4.379
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  27 in total

Review 1.  Mesenchymal Stem Cells on Horizon: A New Arsenal of Therapeutic Agents.

Authors:  Zahra Abbasi-Malati; Amaneh Mohammadi Roushandeh; Yoshikazu Kuwahara; Mehryar Habibi Roudkenar
Journal:  Stem Cell Rev Rep       Date:  2018-08       Impact factor: 5.739

2.  The secretome obtained under hypoxic preconditioning from human adipose-derived stem cells exerts promoted anti-apoptotic potentials through upregulated autophagic process.

Authors:  Haeyeon Seo; Ho Joong Choi; Ok-Hee Kim; Jung Hyun Park; Ha Eun Hong; Say-June Kim
Journal:  Mol Biol Rep       Date:  2022-08-08       Impact factor: 2.742

3.  Advances in Stem Cell-Based Therapy for Hair Loss.

Authors:  Andjela Egger; Marjana Tomic-Canic; Antonella Tosti
Journal:  CellR4 Repair Replace Regen Reprogram       Date:  2020-09-02

4.  Mesenchymal stem cells derivatives as a novel and potential therapeutic approach to treat diabetic foot ulcers.

Authors:  Silvia M Becerra-Bayona; Víctor Alfonso Solarte-David; Claudia L Sossa; Ligia C Mateus; Martha Villamil; Jorge Pereira; Martha L Arango-Rodríguez
Journal:  Endocrinol Diabetes Metab Case Rep       Date:  2020-07-05

Review 5.  Therapeutic mesenchymal stromal stem cells: Isolation, characterization and role in equine regenerative medicine and metabolic disorders.

Authors:  Mohamad Al Naem; Lynda Bourebaba; Katarzyna Kucharczyk; Michael Röcken; Krzysztof Marycz
Journal:  Stem Cell Rev Rep       Date:  2020-04       Impact factor: 5.739

6.  Safety and tolerability of topically administered autologous, apoptotic PBMC secretome (APOSEC) in dermal wounds: a randomized Phase 1 trial (MARSYAS I).

Authors:  Elisabeth Simader; Denise Traxler; Mohammad Mahdi Kasiri; Helmut Hofbauer; Michael Wolzt; Christoph Glogner; Angela Storka; Michael Mildner; Ghazaleh Gouya; Alexandra Geusau; Carola Fuchs; Claudia Eder; Alexandra Graf; Michaela Schaden; Bahar Golabi; Marie-Bernadette Aretin; Susanne Suessner; Christian Gabriel; Walter Klepetko; Erwin Tschachler; Hendrik Jan Ankersmit
Journal:  Sci Rep       Date:  2017-07-24       Impact factor: 4.379

Review 7.  Mesenchymal Stem Cell Secretome: Toward Cell-Free Therapeutic Strategies in Regenerative Medicine.

Authors:  Francisco J Vizoso; Noemi Eiro; Sandra Cid; Jose Schneider; Roman Perez-Fernandez
Journal:  Int J Mol Sci       Date:  2017-08-25       Impact factor: 5.923

Review 8.  Intraovarian injection of autologous human mesenchymal stem cells increases estrogen production and reduces menopausal symptoms in women with premature ovarian failure: two case reports and a review of the literature.

Authors:  Prosper Igboeli; Abdeljabar El Andaloussi; Ujalla Sheikh; Hajra Takala; Amro ElSharoud; Ashley McHugh; Larisa Gavrilova-Jordan; Steven Levy; Ayman Al-Hendy
Journal:  J Med Case Rep       Date:  2020-07-18

Review 9.  Dissecting the Role of Mesenchymal Stem Cells in Idiopathic Pulmonary Fibrosis: Cause or Solution.

Authors:  Anna Valeria Samarelli; Roberto Tonelli; Irene Heijink; Aina Martin Medina; Alessandro Marchioni; Giulia Bruzzi; Ivana Castaniere; Dario Andrisani; Filippo Gozzi; Linda Manicardi; Antonio Moretti; Stefania Cerri; Riccardo Fantini; Luca Tabbì; Chiara Nani; Ilenia Mastrolia; Daniel J Weiss; Massimo Dominici; Enrico Clini
Journal:  Front Pharmacol       Date:  2021-07-05       Impact factor: 5.810

Review 10.  Addressing Stem Cell Therapeutic Approaches in Pathobiology of Diabetes and Its Complications.

Authors:  Bou-Yue Peng; Navneet Kumar Dubey; Viraj Krishna Mishra; Feng-Chou Tsai; Rajni Dubey; Win-Ping Deng; Hong-Jian Wei
Journal:  J Diabetes Res       Date:  2018-06-25       Impact factor: 4.011
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