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Literature DB >> 28470454

Ceylonins G-I: spongian diterpenes from the marine sponge Spongia ceylonensis.

Ahmed H El-Desoky^1,2, Hikaru Kato¹, Sachiko Tsukamoto³.

Abstract

Three new spongian diterpenes, ceylonins G-I (1-3), were isolated from the marine sponge Spongia ceylonensis collected in Indonesia, together with five known spongian diterpenes (4-8). Only 4 inhibited USP7 with an IC50 value of 8.2 μM.

Entities: Chemical Gene

Keywords: Marine sponge; Spongia ceylonensis; Spongian diterpene; USP7

Mesh：

Substances：
Diterpenes

Year: 2017 PMID： 28470454 DOI： 10.1007/s11418-017-1087-4

Source DB: PubMed Journal: J Nat Med ISSN： 1340-3443 Impact factor: 2.343

9 in total

1. Two new spongian diterpenes from Coscinoderma mathewsi.

Authors: M Hyosu; J Kimura
Journal: J Nat Prod Date: 2000-03 Impact factor: 4.050

2. Six new spongian diterpenes from the sponge spongia matamata

Authors:
Journal: J Nat Prod Date: 1999-02 Impact factor: 4.050

3. Discovery of specific inhibitors of human USP7/HAUSP deubiquitinating enzyme.

Authors: Céline Reverdy; Susan Conrath; Roman Lopez; Cécile Planquette; Cédric Atmanene; Vincent Collura; Jane Harpon; Véronique Battaglia; Valérie Vivat; Wolfgang Sippl; Frédéric Colland
Journal: Chem Biol Date: 2012-04-20

4. Ceylonins A-F, Spongian Diterpene Derivatives That Inhibit RANKL-Induced Formation of Multinuclear Osteoclasts, from the Marine Sponge Spongia ceylonensis.

Authors: Ahmed H El-Desoky; Hikaru Kato; Ippei Kagiyama; Yuki Hitora; Fitje Losung; Remy E P Mangindaan; Nicole J de Voogd; Sachiko Tsukamoto
Journal: J Nat Prod Date: 2016-12-27 Impact factor: 4.050

5. Ceylonamides A-F, Nitrogenous Spongian Diterpenes That Inhibit RANKL-Induced Osteoclastogenesis, from the Marine Sponge Spongia ceylonensis.

Authors: Ahmed H El-Desoky; Hikaru Kato; Esther D Angkouw; Remy E P Mangindaan; Nicole J de Voogd; Sachiko Tsukamoto
Journal: J Nat Prod Date: 2016-08-15 Impact factor: 4.050

6. Spongiacidin C, a pyrrole alkaloid from the marine sponge Stylissa massa, functions as a USP7 inhibitor.

Authors: Michitaka Yamaguchi; Mitsue Miyazaki; Matthew P Kodrasov; Henki Rotinsulu; Fitje Losung; Remy E P Mangindaan; Nicole J de Voogd; Hideyoshi Yokosawa; Benjamin Nicholson; Sachiko Tsukamoto
Journal: Bioorg Med Chem Lett Date: 2013-05-03 Impact factor: 2.823

7. Taichunamides: Prenylated Indole Alkaloids from Aspergillus taichungensis (IBT 19404).

Authors: Ippei Kagiyama; Hikaru Kato; Tatsuo Nehira; Jens C Frisvad; David H Sherman; Robert M Williams; Sachiko Tsukamoto
Journal: Angew Chem Int Ed Engl Date: 2015-12-08 Impact factor: 15.336

8. Small-molecule inhibitor of USP7/HAUSP ubiquitin protease stabilizes and activates p53 in cells.

Authors: Frédéric Colland; Etienne Formstecher; Xavier Jacq; Céline Reverdy; Cécile Planquette; Susan Conrath; Virginie Trouplin; Julie Bianchi; Vasily N Aushev; Jacques Camonis; Alessandra Calabrese; Catherine Borg-Capra; Wolfgang Sippl; Vincent Collura; Guillaume Boissy; Jean-Christophe Rain; Philippe Guedat; Rémi Delansorne; Laurent Daviet
Journal: Mol Cancer Ther Date: 2009-08-11 Impact factor: 6.261

9. Activity-based chemical proteomics accelerates inhibitor development for deubiquitylating enzymes.

Authors: Mikael Altun; Holger B Kramer; Lianne I Willems; Jeffrey L McDermott; Craig A Leach; Seth J Goldenberg; K G Suresh Kumar; Rebecca Konietzny; Roman Fischer; Edward Kogan; Mukram M Mackeen; Joanna McGouran; Svetlana V Khoronenkova; Jason L Parsons; Grigory L Dianov; Benjamin Nicholson; Benedikt M Kessler
Journal: Chem Biol Date: 2011-11-23

9 in total

7 in total

1. Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7.

Authors: Ilaria Lamberto; Xiaoxi Liu; Hyuk-Soo Seo; Nathan J Schauer; Roxana E Iacob; Wanyi Hu; Deepika Das; Tatiana Mikhailova; Ellen L Weisberg; John R Engen; Kenneth C Anderson; Dharminder Chauhan; Sirano Dhe-Paganon; Sara J Buhrlage
Journal: Cell Chem Biol Date: 2017-10-19 Impact factor: 8.116

2. An Anti-Inflammatory 2,4-Cyclized-3,4-Secospongian Diterpenoid and Furanoterpene-Related Metabolites of a Marine Sponge Spongia sp. from the Red Sea.

Authors: Chi-Jen Tai; Chiung-Yao Huang; Atallah F Ahmed; Raha S Orfali; Walied M Alarif; Yusheng M Huang; Yi-Hsuan Wang; Tsong-Long Hwang; Jyh-Horng Sheu
Journal: Mar Drugs Date: 2021-01-16 Impact factor: 5.118

Review 3. Marine Pharmacology in 2016-2017: Marine Compounds with Antibacterial, Antidiabetic, Antifungal, Anti-Inflammatory, Antiprotozoal, Antituberculosis and Antiviral Activities; Affecting the Immune and Nervous Systems, and Other Miscellaneous Mechanisms of Action.

Authors: Alejandro M S Mayer; Aimee J Guerrero; Abimael D Rodríguez; Orazio Taglialatela-Scafati; Fumiaki Nakamura; Nobuhiro Fusetani
Journal: Mar Drugs Date: 2021-01-21 Impact factor: 5.118