Handan Akil1, Anna Dastiridou1, Kenneth Marion1, Brian Francis2, Vikas Chopra3. 1. Doheny Eye Institute, Doheny Image Reading Center, Los Angeles, California. 2. Doheny Eye Institute, Doheny Image Reading Center, Los Angeles, California; Department of Ophthalmology, David Geffen School of Medicine, Los Angeles, California. 3. Doheny Eye Institute, Doheny Image Reading Center, Los Angeles, California; Department of Ophthalmology, David Geffen School of Medicine, Los Angeles, California. Electronic address: vchopra@doheny.org.
Abstract
OBJECTIVE: To evaluate the agreement, reproducibility, and repeatability of 2 spectral domain optical coherence tomography (SD-OCT) devices in Schwalbe's line (SL)-based anterior chamber angle parameters. METHODS: The inferior anterior chamber angle of 65 eyes from 65 participants (33 right eyes and 32 left eyes) were scanned twice with the Nidek RS 3000 Advanced SD-OCT and Cirrus SD-OCT. SL angle opening distance (SL-AOD) and SL trabecular-iris-space area (SL-TISA) were graded by masked certified graders at the Doheny Image Reading Center. RESULTS: The mean SL-AOD/SL-TISA was 617.3 ± 237.9 µm/0.211 ± 0.086 mm2 for the Cirrus and 633.7 ± 219.3 µm/0.218 ± 0.080 mm2 for the Nidek RS 3000 Advanced SD-OCT. The repeatability (intraclass correlation coefficients [ICCs] >0.936) and intergrader reproducibility (ICCs >0.915) in SL-AOD and SL-TISA with Cirrus OCT were excellent. The repeatability (ICCs >0.948) and intergrader reproducibility (ICCs >0.709) in SL-AOD and SL-TISA with the Nidek RS 3000 Advanced SD-OCT were moderate to good. Moderate agreement between the 2 devices was also documented with a mean difference of -15.3 (limits of agreement [LoA] -246.5 to 277.1) mm for SL-AOD and 0.006 (LoA -0.096 to 0.108) mm in SL-TISA. CONCLUSION: Both devices were able to provide consistent angle measurements, but repeatability and reproducibility were better in Cirrus SD-OCT than in Nidek RS 3000 Advanced SD-OCT.
OBJECTIVE: To evaluate the agreement, reproducibility, and repeatability of 2 spectral domain optical coherence tomography (SD-OCT) devices in Schwalbe's line (SL)-based anterior chamber angle parameters. METHODS: The inferior anterior chamber angle of 65 eyes from 65 participants (33 right eyes and 32 left eyes) were scanned twice with the Nidek RS 3000 Advanced SD-OCT and Cirrus SD-OCT. SL angle opening distance (SL-AOD) and SL trabecular-iris-space area (SL-TISA) were graded by masked certified graders at the Doheny Image Reading Center. RESULTS: The mean SL-AOD/SL-TISA was 617.3 ± 237.9 µm/0.211 ± 0.086 mm2 for the Cirrus and 633.7 ± 219.3 µm/0.218 ± 0.080 mm2 for the Nidek RS 3000 Advanced SD-OCT. The repeatability (intraclass correlation coefficients [ICCs] >0.936) and intergrader reproducibility (ICCs >0.915) in SL-AOD and SL-TISA with Cirrus OCT were excellent. The repeatability (ICCs >0.948) and intergrader reproducibility (ICCs >0.709) in SL-AOD and SL-TISA with the Nidek RS 3000 Advanced SD-OCT were moderate to good. Moderate agreement between the 2 devices was also documented with a mean difference of -15.3 (limits of agreement [LoA] -246.5 to 277.1) mm for SL-AOD and 0.006 (LoA -0.096 to 0.108) mm in SL-TISA. CONCLUSION: Both devices were able to provide consistent angle measurements, but repeatability and reproducibility were better in Cirrus SD-OCT than in Nidek RS 3000 Advanced SD-OCT.
Authors: E Randy Craven; Vikas Chopra; Jeffrey L Goldberg; Kenneth M Marion; Xiaoming Chen; Cheng-Tao Chang; Michelle Y Chen Journal: Clin Ophthalmol Date: 2022-04-27