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Literature DB >> 28453929

Synthesis of Lipophilic Core-Shell Fe₃O₄@SiO₂@Au Nanoparticles and Polymeric Entrapment into Nanomicelles: A Novel Nanosystem for in Vivo Active Targeting and Magnetic Resonance-Photoacoustic Dual Imaging.

Ilaria Monaco¹, Francesca Arena², Stefania Biffi³, Erica Locatelli¹, Barbara Bortot³, Francesca La Cava², Giada Maria Marini², Giovanni Maria Severini³, Enzo Terreno², Mauro Comes Franchini¹.

Abstract

In this work, iron/silica/gold core-shell nanoparticles (Fe3O4@SiO2@Au NPs) characterized by magnetic and optical properties have been synthesized to obtain a promising theranostic platform. To improve their biocompatibility, the obtained multilayer nanoparticles have been entrapped in polymeric micelles, decorated with folic acid moieties, and tested in vivo for photoacoustic and magnetic resonance imaging detection of ovarian cancer.

Entities: Chemical Disease

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Year: 2017 PMID： 28453929 DOI： 10.1021/acs.bioconjchem.7b00076

Source DB: PubMed Journal: Bioconjug Chem ISSN： 1043-1802 Impact factor: 4.774

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Cited

12 in total

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Synthesis of Lipophilic Core-Shell Fe₃O₄@SiO₂@Au Nanoparticles and Polymeric Entrapment into Nanomicelles: A Novel Nanosystem for in Vivo Active Targeting and Magnetic Resonance-Photoacoustic Dual Imaging.

1. Efficient and selective catalytic hydroxylation of unsaturated plant oils: a novel method for producing anti-pathogens.

Review 2. Multifunctional nanomedicine with silica: Role of silica in nanoparticles for theranostic, imaging, and drug monitoring.

Review 3. Magnetic iron oxide nanoparticles for imaging, targeting and treatment of primary and metastatic tumors of the brain.

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Review 10. Fe₃O₄ Nanoparticles in Targeted Drug/Gene Delivery Systems.