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Literature DB >> 28443194

⁶⁸Ga-DOTA and analogs: Current status and future perspectives.

Abstract

The construction of the 68Ge/68Ga generator has increased application of radiopharmaceuticals labeled with this isotope in medicine. 68Ga-PET is widely employed in the management of neuroendocrine tumors but favorable chemistry with tri- and tetraaza-ring molecules has opened wide range of 68Ga application in other fields of PET imaging. This review covers the radiopharmaceuticals labeled with gallium in molecular imaging and shows perspectives on the use of gallium-68 as a substitute for technetium-99, fluorine-18 and carbon-11 in some applications.

Entities: Chemical Disease

Keywords: 68Ga labeled compounds; 68Gallium-DOTA-peptides; Bifunctional chelators; Position emission tomography

Year: 2014 PMID： 28443194 PMCID： PMC5394743 DOI： 10.1016/j.rpor.2014.04.016

Source DB: PubMed Journal: Rep Pract Oncol Radiother ISSN： 1507-1367

67 in total

Review 1. Modern PET imaging for paragangliomas: relation to genetic mutations.

Authors: D Taïeb; D Rubello; A Al-Nahhas; M Calzada; M C Marzola; E Hindié
Journal: Eur J Surg Oncol Date: 2011-06-01 Impact factor: 4.424

2. In vivo testing of 177Lu-labelled anti-PSMA antibody as a new radioimmunotherapeutic agent against prostate cancer.

Authors: Martin Behe; Karen Alt; Friederike Deininger; Patrick Bühler; Ulrich Wetterauer; Wolfgang A Weber; Ursula Elsässer-Beile; Philipp Wolf
Journal: In Vivo Date: 2011 Jan-Feb Impact factor: 2.155

3. Radiolabelling, quality control and radiochemical purity assessment of the Octreotide analogue 68Ga DOTA NOC.

Authors: D Di Pierro; A Rizzello; G Cicoria; F Lodi; M Marengo; D Pancaldi; S Trespidi; S Boschi
Journal: Appl Radiat Isot Date: 2007-12-08 Impact factor: 1.513

4. Full automation of (68)Ga labelling of DOTA-peptides including cation exchange prepurification.

Authors: M Ocak; M Antretter; R Knopp; F Kunkel; M Petrik; N Bergisadi; C Decristoforo
Journal: Appl Radiat Isot Date: 2009-10-24 Impact factor: 1.513

Review 5. (68)Ga-labeled DOTA-peptides and (68)Ga-labeled radiopharmaceuticals for positron emission tomography: current status of research, clinical applications, and future perspectives.

Authors: Wouter A P Breeman; Erik de Blois; Ho Sze Chan; Mark Konijnenberg; Dik J Kwekkeboom; Eric P Krenning
Journal: Semin Nucl Med Date: 2011-07 Impact factor: 4.446

Review 6. Automation synthesis modules review.

Authors: S Boschi; F Lodi; C Malizia; G Cicoria; M Marengo
Journal: Appl Radiat Isot Date: 2012-09-26 Impact factor: 1.513

7. Synthesis and in vitro evaluation of 68Ga-DOTA-4-FBn-TN14003, a novel tracer for the imaging of CXCR4 expression.

Authors: Ute Hennrich; Lisa Seyler; Martin Schäfer; Ulrike Bauder-Wüst; Michael Eisenhut; Wolfhard Semmler; Tobias Bäuerle
Journal: Bioorg Med Chem Date: 2012-01-02 Impact factor: 3.641

8. Infrared-based module for the synthesis of 68Ga-labeled radiotracers.

Authors: Ali Azhdarinia; David J Yang; Clifford Chao; Firas Mourtada
Journal: Nucl Med Biol Date: 2007-01 Impact factor: 2.408

9. 68Ga-DOTA-TATE PET vs. 123I-MIBG in identifying malignant neural crest tumours.

Authors: Meeran Naji; Chunlei Zhao; Sarah J Welsh; Richard Meades; Zarni Win; Annalisa Ferrarese; Tricia Tan; Domenico Rubello; Adil Al-Nahhas
Journal: Mol Imaging Biol Date: 2011-08 Impact factor: 3.488

10. Comparison of 68Ga-DOTATOC PET and 111In-DTPAOC (Octreoscan) SPECT in patients with neuroendocrine tumours.

Authors: I Buchmann; M Henze; S Engelbrecht; M Eisenhut; A Runz; M Schäfer; T Schilling; S Haufe; T Herrmann; U Haberkorn
Journal: Eur J Nucl Med Mol Imaging Date: 2007-05-23 Impact factor: 9.236

11 in total

Review 1. An overview of the developments and potential applications of ⁶⁸Ga-labelled PET/CT hypoxia imaging.

Authors: Philippa L Bresser; Mariza Vorster; Mike M Sathekge
Journal: Ann Nucl Med Date: 2021-01-05 Impact factor: 2.668

2. Multiwalled Carbon Nanotubes for Combination Therapy: a Biodistribution and Efficacy Pilot Study.

Authors: Giacomo Biagiotti; Federica Pisaneschi; Seth T Gammon; Fabrizio Machetti; Maria Cristina Ligi; Giuliano Giambastiani; Giulia Tuci; Emily Powell; Helen Piwnica-Worms; Erica Pranzini; Paolo Paoli; Stefano Cicchi; David Piwnica-Worms
Journal: J Mater Chem B Date: 2019-03-12 Impact factor: 6.331

Review 3. Porphyrins as Chelating Agents for Molecular Imaging in Nuclear Medicine.

Authors: Krystyna Pyrzynska; Krzysztof Kilian; Mateusz Pęgier
Journal: Molecules Date: 2022-05-21 Impact factor: 4.927

4. ⁶⁸Ga-DOTANOC and ¹⁸F-FDG PET/CT in metastatic medullary thyroid carcinoma: novel correlations with tumoral biomarkers.

Authors: Pedro Souteiro; Patrícia Gouveia; Gonçalo Ferreira; Sandra Belo; Cláudia Costa; Davide Carvalho; Hugo Duarte; Inês Lucena Sampaio
Journal: Endocrine Date: 2019-01-25 Impact factor: 3.633

5. Evaluation of F-18 DOPA PET/CT in the detection of recurrent or metastatic medullary thyroid carcinoma: comparison with GA-68 DOTA-TATE PET/CT.

Authors: Sertac Asa; Kerim Sonmezoglu; Lebriz Uslu-Besli; Onur Erdem Sahin; Emre Karayel; Huseyin Pehlivanoglu; Sait Sager; Levent Kabasakal; Meltem Ocak; Haluk B Sayman
Journal: Ann Nucl Med Date: 2021-05-15 Impact factor: 2.668

6. Radiolabeling and Preclinical Evaluation of a New S-Alkylated Cysteine Derivative Conjugated to C-Substituted Macrocycle for Positron Emission Tomography.

Authors: Surbhi Prakash; Puja Panwar Hazari; Virendra Kumar Meena; Anil Kumar Mishra
Journal: ACS Omega Date: 2018-06-18

Review 7. Molecular Imaging in Pediatric Brain Tumors.

Authors: Agostino Chiaravalloti; Luca Filippi; Maria Ricci; Andrea Cimini; Orazio Schillaci
Journal: Cancers (Basel) Date: 2019-11-23 Impact factor: 6.639

8. Development of ⁶⁸Ga-Labeled Hepatitis E Virus Nanoparticles for Targeted Drug Delivery and Diagnostics with PET.

Authors: Elisavet Lambidis; Chun-Chieh Chen; Mo Baikoghli; Surachet Imlimthan; You Cheng Khng; Mirkka Sarparanta; R Holland Cheng; Anu J Airaksinen
Journal: Mol Pharm Date: 2022-07-20 Impact factor: 5.364

9. Synthesis, Radiolabeling, and Preliminary in vivo Evaluation of [⁶⁸Ga] IPCAT-NOTA as an Imaging Agent for Dopamine Transporter.

Authors: Shiou-Shiow Farn; Kang-Wei Chang; Wan-Chi Lin; Hung-Man Yu; Kun-Liang Lin; Yu-Chin Tseng; Yu Chang; Chung-Shan Yu; Wuu-Jyh Lin
Journal: Drug Des Devel Ther Date: 2021-06-17 Impact factor: 4.162

Review 10. Antibody Fragment and Affibody ImmunoPET Imaging Agents: Radiolabelling Strategies and Applications.

Authors: Ruisi Fu; Laurence Carroll; Gokhan Yahioglu; Eric O Aboagye; Philip W Miller
Journal: ChemMedChem Date: 2018-11-15 Impact factor: 3.466