Literature DB >> 23084477

Automation synthesis modules review.

S Boschi1, F Lodi, C Malizia, G Cicoria, M Marengo.   

Abstract

The introduction of (68)Ga labelled tracers has changed the diagnostic approach to neuroendocrine tumours and the availability of a reliable, long-lived (68)Ge/(68)Ga generator has been at the bases of the development of (68)Ga radiopharmacy. The huge increase in clinical demand, the impact of regulatory issues and a careful radioprotection of the operators have boosted for extensive automation of the production process. The development of automated systems for (68)Ga radiochemistry, different engineering and software strategies and post-processing of the eluate were discussed along with impact of automation with regulations.
Copyright © 2012 Elsevier Ltd. All rights reserved.

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Year:  2012        PMID: 23084477     DOI: 10.1016/j.apradiso.2012.09.010

Source DB:  PubMed          Journal:  Appl Radiat Isot        ISSN: 0969-8043            Impact factor:   1.513


  14 in total

Review 1.  68Ga-DOTA and analogs: Current status and future perspectives.

Authors:  Krzysztof Kilian
Journal:  Rep Pract Oncol Radiother       Date:  2014-05-19

2.  Green and efficient synthesis of the radiopharmaceutical [18F]FDOPA using a microdroplet reactor.

Authors:  Jia Wang; Travis Holloway; Ksenia Lisova; R Michael van Dam
Journal:  React Chem Eng       Date:  2019-12-13       Impact factor: 4.239

Review 3.  The Molecular Industrial Revolution: Automated Synthesis of Small Molecules.

Authors:  Melanie Trobe; Martin D Burke
Journal:  Angew Chem Int Ed Engl       Date:  2018-03-07       Impact factor: 15.336

4.  Fully automated production of diverse 18F-labeled PET tracers on the ELIXYS multireactor radiosynthesizer without hardware modification.

Authors:  Mark Lazari; Jeffrey Collins; Bin Shen; Mohammed Farhoud; Daniel Yeh; Brandon Maraglia; Frederick T Chin; David A Nathanson; Melissa Moore; R Michael van Dam
Journal:  J Nucl Med Technol       Date:  2014-07-17

5.  Development of single vial kits for preparation of (68)Ga-labelled peptides for PET imaging of neuroendocrine tumours.

Authors:  Archana Mukherjee; Usha Pandey; Rubel Chakravarty; Haladhar Dev Sarma; Ashutosh Dash
Journal:  Mol Imaging Biol       Date:  2014-08       Impact factor: 3.488

6.  GMP-compliant (68)Ga radiolabelling in a conventional small-scale radiopharmacy: a feasible approach for routine clinical use.

Authors:  Roeland Vis; Jules Lavalaye; Ewoudt Mw van de Garde
Journal:  EJNMMI Res       Date:  2015-04-24       Impact factor: 3.138

7.  Automated astatination of biomolecules--a stepping stone towards multicenter clinical trials.

Authors:  Emma Aneheim; Per Albertsson; Tom Bäck; Holger Jensen; Stig Palm; Sture Lindegren
Journal:  Sci Rep       Date:  2015-07-14       Impact factor: 4.379

8.  Simplified programming and control of automated radiosynthesizers through unit operations.

Authors:  Shane B Claggett; Kevin M Quinn; Mark Lazari; Melissa D Moore; R Michael van Dam
Journal:  EJNMMI Res       Date:  2013-07-15       Impact factor: 3.138

9.  Interdisciplinary Tasks in the Cyclotron Production of Radiometals for Medical Applications. The Case of 47Sc as Example.

Authors:  Alessandra Boschi; Petra Martini; Valentina Costa; Antonella Pagnoni; Licia Uccelli
Journal:  Molecules       Date:  2019-01-26       Impact factor: 4.411

Review 10.  68Ga-Based radiopharmaceuticals: production and application relationship.

Authors:  Irina Velikyan
Journal:  Molecules       Date:  2015-07-16       Impact factor: 4.411

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