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Literature DB >> 284416

IgM receptors on human lymphocytes: detection by direct binding.

Abstract

Radioiodinated IgM isolated from a patient with Waldenström macroglobulinemia binds with high avidity (apparent Ka = 2.5 x 10(9) M-1) to freshly isolated human peripheral blood lymphocytes. Binding occurred through the Fc region of the molecule and involved a receptor specific for immunoglobulins of the IgM class. The avidity and specificity of this binding are consistent with a biologic role for IgM receptors on lymphocytes.

Entities: Disease Species

Mesh：

Substances：

Year: 1979 PMID： 284416 PMCID： PMC383091 DOI： 10.1073/pnas.76.2.912

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

15 in total

1. Structural units of human 7S gamma globulin.

Authors: E C FRANKLIN
Journal: J Clin Invest Date: 1960-12 Impact factor: 14.808

2. Receptors for IgM on certain human B lymphocytes.

Authors: M Ferrarini; T Hoffman; S M Fu; R Winchester; H G Kunkel
Journal: J Immunol Date: 1977-10 Impact factor: 5.422

3. Human T lymphocyte receptors for IgM: reactivity with monomeric 8S subunit.

Authors: J L Preud'homme; M Gonnot; A Tsapis; J C Brouet; C Mihaesco
Journal: J Immunol Date: 1977-12 Impact factor: 5.422

4. Mechanisms of passive sensitization. 3. Number of IgE molecules and their receptor sites on human basophil granulocytes.

Authors: T Ishizaka; C S Soto; K Ishizaka
Journal: J Immunol Date: 1973-08 Impact factor: 5.422

10. Functional analysis of two human T-cell subpopulations: help and suppression of B-cell responses by T cells bearing receptors for IgM or IgG.

Authors: L Moretta; S R Webb; C E Grossi; P M Lydyard; M D Cooper
Journal: J Exp Med Date: 1977-07-01 Impact factor: 14.307

4 in total

IgM receptors on human lymphocytes: detection by direct binding.

1. Structural units of human 7S gamma globulin.

2. Receptors for IgM on certain human B lymphocytes.

3. Human T lymphocyte receptors for IgM: reactivity with monomeric 8S subunit.

4. Mechanisms of passive sensitization. 3. Number of IgE molecules and their receptor sites on human basophil granulocytes.

5. Cmu4 domain of IgM has cytophilic activity for human lymphocytes.

6. Immunoglobulin M: pentameric Fcmu fragments released by trypsin at higher temperatures.

7. Human T cell receptor for IgM: specificity for the pentameric Fc fragment.

8. Lymphocyte receptors. II. Receptors for rabbit IgM on human T lymphocytes.

9. Tissue factor activity in lymphocyte cultures from normal individuals and patients with hemophilia A.

10. Functional analysis of two human T-cell subpopulations: help and suppression of B-cell responses by T cells bearing receptors for IgM or IgG.

Review 1. Characteristics and function of Fc receptors on human lymphocytes.

2. Binding of different ligands to IgM-Fc receptors of rat leucocytes.

Review 3. [The significance of Fc-IgG and Fc-IgM receptors on human T-lymphocytes (author's transl)].

4. Molecular cloning of two CD7 (T-cell leukemia antigen) cDNAs by a COS cell expression system.