Literature DB >> 1086790

Human T cell receptor for IgM: specificity for the pentameric Fc fragment.

M Ferrarini, L Moretta, M C Mingari, P Tonda, B Pernis.   

Abstract

The specificity of the IgM receptor expressed by human T cells cultured in IgM-free media has been investigated. IgM receptors have been detected using a rosette system with ox erythrocytes coated with rabbit antibody (EA(IgM)), and the inhibitory capacity of different IgM fragments in the rosette system has been tested. It was found that F(c)5mu but not F(ab')2mu, nor monomeric IgM (8 S IgM) inhibited EA (IgM) rosette-forming cells. This indicates that the receptor present on the surface of T cells has affinity for a structure located in the Fc portion of the pentameric IgM.

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Year:  1976        PMID： 1086790     DOI： 10.1002/eji.1830060714

Source DB:  PubMed          Journal:  Eur J Immunol        ISSN： 0014-2980            Impact factor:   5.532


  14 in total

1.  MICC cytotoxic effector function of human T lymphocyte subpopulations bearing Fc-receptors for IgG and IgM.

Authors:  L G Lum; A V Muchmore; J M Decker; R M Blaese
Journal:  Clin Exp Immunol       Date:  1979-09       Impact factor: 4.330

2.  The differential effect of in vivo hydrocortisone on the kinetics of subpopulations of human peripheral blood thymus-derived lymphocytes.

Authors:  B F Haynes; A S Fauci
Journal:  J Clin Invest       Date:  1978-03       Impact factor: 14.808

3.  Selective blocking of T cell-mediated in vitro cytotoxicity to a xenogeneic tumour by anti-immunoglobulin sera.

Authors:  E S Newlands; F C Hay; I M Roitt
Journal:  Clin Exp Immunol       Date:  1978-02       Impact factor: 4.330

4.  [Intercellular contacts in chronic rhinosinusitis and their possible significance. A light and electron microscopic investigation (author's transl)].

Authors:  K W Albegger; G P Tilz
Journal:  Arch Otorhinolaryngol       Date:  1977-05-31

5.  Neuraminidase- and trypsin-induced exposure to membrane receptors for IgG and IgM molecules on human peripheral blood lymphocytes.

Authors:  D G Haegert
Journal:  Clin Exp Immunol       Date:  1977-09       Impact factor: 4.330

6.  Nonspecific esterase as a marker for human T-lymphocytes sequential studies during states of transient blood lymphocyte redistribution.

Authors:  J Fehr; O Scherer
Journal:  Blut       Date:  1982-04

7.  IgD-Fc receptors on normal and neoplastic human B lymphocytes.

Authors:  R A Rudders; J Andersen
Journal:  Clin Exp Immunol       Date:  1982-12       Impact factor: 4.330

Review 8.  [The significance of Fc-IgG and Fc-IgM receptors on human T-lymphocytes (author's transl)].

Authors:  W J Pichler
Journal:  Klin Wochenschr       Date:  1981-02-02

9.  The in vitro culture characteristics and requirements for expression of receptors for IgM on human peripheral blood lymphocytes.

Authors:  M G Golightly; S H Golub
Journal:  Clin Exp Immunol       Date:  1980-01       Impact factor: 4.330

10.  IgM receptors on human lymphocytes: detection by direct binding.

Authors:  J A Hardin; K K Nakaoka; J M Carboni
Journal:  Proc Natl Acad Sci U S A       Date:  1979-02       Impact factor: 11.205
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