Literature DB >> 284353

Monoclonal antibodies reacting with murine teratocarcinoma cells.

P N Goodfellow, J R Levinson, V E Williams, H O McDevitt.   

Abstract

Monoclonal antibodies were produced in vitro by fusing mouse myeloma cells with spleen cells from a rat immunized with the C3H mouse teratocarcinoma C86-S1. After the fusion two clones were chosen for further analysis. The first clone, 3C4-10, produced an antibody recognizing an antigen with a distribution restricted to teratocarcinoma cell lines, an endoderm cell line, and a neuroblastoma. The second clone, 4A1-9, produced an antibody that reacted with all cultured murine cells tested and adult brain. Neither antibody reacted with preimplantation embryos. The 3C4-10 antibody recognized an antigen associated with proteins. The apparent molecular weight of the 3C4-10 antigen was greater than 100,000.

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Year:  1979        PMID： 284353      PMCID： PMC382942          DOI： 10.1073/pnas.76.1.377

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  26 in total

1.  Cell surface antigens of totipotent mouse teratocarcinoma cells grown in vivo: their relation to embryo, adult, and tumor antigens.

Authors:  M J Dewey; J D Gearhart; B Mintz
Journal:  Dev Biol       Date:  1977-02       Impact factor: 3.582

2.  Virus infection of murine teratocarcinoma stem cell lines.

Authors:  N M Teich; R A Weiss; G R Martin; D R Lowy
Journal:  Cell       Date:  1977-12       Impact factor: 41.582

3.  Teratocarcinoma X friend erythroleukemia cell hybrids resemble their pluripotent embryonal carcinoma parent.

Authors:  R A Miller; F H Ruddle
Journal:  Dev Biol       Date:  1977-03       Impact factor: 3.582

4.  Antibodies to major histocompatibility antigens produced by hybrid cell lines.

Authors:  G Galfre; S C Howe; C Milstein; G W Butcher; J C Howard
Journal:  Nature       Date:  1977-04-07       Impact factor: 49.962

5.  PCC4, a new cell surface antigen common to multipotential embryonal carcinoma cells, spermatozoa, and mouse early embryos.

Authors:  G Gachelin; R Kemler; F Kelly; F Jacob
Journal:  Dev Biol       Date:  1977-05       Impact factor: 3.582

6.  Monoclonal antibody detecting a stage-specific embryonic antigen (SSEA-1) on preimplantation mouse embryos and teratocarcinoma cells.

Authors:  B B Knowles; D P Aden; D Solter
Journal:  Curr Top Microbiol Immunol       Date:  1978       Impact factor: 4.291

7.  Hybrid plasmacytoma production: fusions with adult spleen cells, monoclonal spleen fragments, neonatal spleen cells and human spleen cells.

Authors:  R H Kennett; K A Denis; A S Tung; N R Klinman
Journal:  Curr Top Microbiol Immunol       Date:  1978       Impact factor: 4.291

8.  Cytoplasmic inheritance of rutamycin resistance in mouse fibroblasts.

Authors:  T Lichtor; G S Getz
Journal:  Proc Natl Acad Sci U S A       Date:  1978-01       Impact factor: 11.205

9.  Surface antigen in early differentiation.

Authors:  R Kemler; C Babinet; H Eisen; F Jacob
Journal:  Proc Natl Acad Sci U S A       Date:  1977-10       Impact factor: 11.205

10.  Monoclonal antibodies as probes for differentiation and tumor-associated antigens: a Forssman specificity on teratocarcinoma stem cells.

Authors:  P L Stern; K R Willison; E Lennox; G Galfrè; C Milstein; D Secher; A Ziegler
Journal:  Cell       Date:  1978-08       Impact factor: 41.582
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  13 in total

1.  Analysis of HLA-D region-associated molecules with monoclonal antibody.

Authors:  D J Charron; H O McDevitt
Journal:  Proc Natl Acad Sci U S A       Date:  1979-12       Impact factor: 11.205

2.  Evidence of a preferential inactivation of the paternally derived X chromosome in a 46,XX true hermaphrodite.

Authors:  C Boucekkine; D Nafa; M Casanova-Bettane; F Latron; M Fellous; M Benmiloud
Journal:  Hum Genet       Date:  1985       Impact factor: 4.132

Review 3.  Hybridomas: a new dimension in biological analyses.

Authors:  R H Kennett
Journal:  In Vitro       Date:  1981-12

Review 4.  Whither monoclonal antibodies?

Authors:  N A Staines; A M Lew
Journal:  Immunology       Date:  1980-07       Impact factor: 7.397

5.  Immunologic recognition of cell surface antigens in normal mouse neural tissues and in neuroepithelial cells of the OTT-6050 mouse teratoma. A radiometric, gel electrophoretic and morphologic (immunofluorescence and immunoperoxidase) study.

Authors:  P B Ramsay; S R VandenBerg; L F Eng; M M Herman; L J Rubinstein
Journal:  Acta Neuropathol       Date:  1982       Impact factor: 17.088

6.  Prevention of diabetes in nonobese diabetic mice by anti-I-A monoclonal antibodies: transfer of protection by splenic T cells.

Authors:  C Boitard; A Bendelac; M F Richard; C Carnaud; J F Bach
Journal:  Proc Natl Acad Sci U S A       Date:  1988-12       Impact factor: 11.205

7.  Characterization of a new human cell line derived from a xenografted embryonal carcinoma.

Authors:  C Cotte; D Raghavan; R A McIlhinney; P Monaghan
Journal:  In Vitro       Date:  1982-09

8.  Isolation and quantitation of the platelet membrane glycoprotein deficient in thrombasthenia using a monoclonal hybridoma antibody.

Authors:  R P McEver; N L Baenziger; P W Majerus
Journal:  J Clin Invest       Date:  1980-12       Impact factor: 14.808

9.  Immunohistochemical localization of murine stage-specific embryonic antigens in human testicular germ cell tumors.

Authors:  I Damjanov; N Fox; B B Knowles; D Solter; P H Lange; E E Fraley
Journal:  Am J Pathol       Date:  1982-08       Impact factor: 4.307

10.  Monoclonal antibodies against beta nerve growth factor and their effects on receptor binding and biological activity.

Authors:  A Zimmermann; A Sutter; E M Shooter
Journal:  Proc Natl Acad Sci U S A       Date:  1981-07       Impact factor: 11.205
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