Literature DB >> 28430753

Impact of Chlorhexidine Cord Cleansing on Mortality, Omphalitis and Cord Separation Time Among Facility-Born Babies in Nepal and Bangladesh.

Luke C Mullany1, Shams El Arifeen, Subarna K Khatry, Joanne Katz, Rashed Shah, Abdullah H Baqui, James M Tielsch.   

Abstract

Guidance is needed regarding potential extension of the World Health Organization recommendation for cord cleansing with chlorhexidine to babies born in facilities. Among 3223 facility-born babies from Nepal and Bangladesh, mortality was approximately halved among those allocated to the intervention clusters [10.5/1000 vs. 19.4/1000; relative risk (RR): 0.54; 95% confidence interval: 0.30-0.97]. In high-mortality settings, a single policy for home and facility births is warranted.

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Year:  2017        PMID： 28430753      PMCID： PMC5600668          DOI： 10.1097/INF.0000000000001617

Source DB:  PubMed          Journal:  Pediatr Infect Dis J        ISSN： 0891-3668            Impact factor:   2.129


  11 in total

1.  Development of clinical sign based algorithms for community based assessment of omphalitis.

Authors:  L C Mullany; G L Darmstadt; J Katz; S K Khatry; S C LeClerq; R K Adhikari; J M Tielsch
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  2005-10-13       Impact factor: 5.747

2.  Efficacy of chlorhexidine application to umbilical cord on neonatal mortality in Pemba, Tanzania: a community-based randomised controlled trial.

Authors:  Sunil Sazawal; Usha Dhingra; Said M Ali; Arup Dutta; Saikat Deb; Shaali M Ame; Mkasha H Mkasha; Ashish Yadav; Robert E Black
Journal:  Lancet Glob Health       Date:  2016-09-29       Impact factor: 26.763

3.  Topical application of chlorhexidine to neonatal umbilical cords for prevention of omphalitis and neonatal mortality in a rural district of Pakistan: a community-based, cluster-randomised trial.

Authors:  Sajid Soofi; Simon Cousens; Aamer Imdad; Naveed Bhutto; Nabeela Ali; Zulfiqar A Bhutta
Journal:  Lancet       Date:  2012-02-08       Impact factor: 79.321

4.  The effect of cord cleansing with chlorhexidine on neonatal mortality in rural Bangladesh: a community-based, cluster-randomised trial.

Authors:  Shams El Arifeen; Luke C Mullany; Rasheduzzaman Shah; Ishtiaq Mannan; Syed M Rahman; M Radwanur R Talukder; Nazma Begum; Ahmed Al-Kabir; Gary L Darmstadt; Mathuram Santosham; Robert E Black; Abdullah H Baqui
Journal:  Lancet       Date:  2012-02-08       Impact factor: 79.321

5.  Effectiveness of 4% chlorhexidine umbilical cord care on neonatal mortality in Southern Province, Zambia (ZamCAT): a cluster-randomised controlled trial.

Authors:  Katherine E A Semrau; Julie Herlihy; Caroline Grogan; Kebby Musokotwane; Kojo Yeboah-Antwi; Reuben Mbewe; Bowen Banda; Chipo Mpamba; Fern Hamomba; Portipher Pilingana; Andisen Zulu; Pascalina Chanda-Kapata; Godfrey Biemba; Donald M Thea; William B MacLeod; Jonathon L Simon; Davidson H Hamer
Journal:  Lancet Glob Health       Date:  2016-09-29       Impact factor: 26.763

6.  Impact of umbilical cord cleansing with 4.0% chlorhexidine on time to cord separation among newborns in southern Nepal: a cluster-randomized, community-based trial.

Authors:  Luke C Mullany; Gary L Darmstadt; Subarna K Khatry; Steven C LeClerq; Joanne Katz; James M Tielsch
Journal:  Pediatrics       Date:  2006-11       Impact factor: 7.124

7.  Topical applications of chlorhexidine to the umbilical cord for prevention of omphalitis and neonatal mortality in southern Nepal: a community-based, cluster-randomised trial.

Authors:  Luke C Mullany; Gary L Darmstadt; Subarna K Khatry; Joanne Katz; Steven C LeClerq; Shardaram Shrestha; Ramesh Adhikari; James M Tielsch
Journal:  Lancet       Date:  2006-03-18       Impact factor: 79.321

8.  Chlorhexidine cleansing of the umbilical cord and separation time: a cluster-randomized trial.

Authors:  Luke C Mullany; Rasheduzzaman Shah; Shams El Arifeen; Ishtiaq Mannan; Peter J Winch; Amber Hill; Gary L Darmstadt; Abdullah H Baqui
Journal:  Pediatrics       Date:  2013-03-18       Impact factor: 7.124

Review 9.  Quality maternity care for every woman, everywhere: a call to action.

Authors:  Marjorie Koblinsky; Cheryl A Moyer; Clara Calvert; James Campbell; Oona M R Campbell; Andrea B Feigl; Wendy J Graham; Laurel Hatt; Steve Hodgins; Zoe Matthews; Lori McDougall; Allisyn C Moran; Allyala K Nandakumar; Ana Langer
Journal:  Lancet       Date:  2016-09-16       Impact factor: 79.321

Review 10.  The effect of umbilical cord cleansing with chlorhexidine on omphalitis and neonatal mortality in community settings in developing countries: a meta-analysis.

Authors:  Aamer Imdad; Luke C Mullany; Abdullah H Baqui; Shams El Arifeen; James M Tielsch; Subarna K Khatry; Rasheduzzaman Shah; Simon Cousens; Robert E Black; Zulfiqar A Bhutta
Journal:  BMC Public Health       Date:  2013-09-17       Impact factor: 3.295
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  2 in total

Review 1.  Effect of chlorhexidine cord application on prevention of neonatal sepsis in developing countries: Systematic review and meta-analysis.

Authors:  Tilayie Feto Gelano; Yadeta Dassie Bacha; Degu Abate
Journal:  Int J Health Sci (Qassim)       Date:  2019 Jan-Feb

2.  Chlorhexidine for facility-based umbilical cord care: EN-BIRTH multi-country validation study.

Authors:  Joy E Lawn; Shams El Arifeen; Sojib Bin Zaman; Abu Bakkar Siddique; Harriet Ruysen; Ashish Kc; Kimberly Peven; Shafiqul Ameen; Nishant Thakur; Qazi Sadeq-Ur Rahman; Nahya Salim; Rejina Gurung; Tazeen Tahsina; Ahmed Ehsanur Rahman; Patricia S Coffey; Barbara Rawlins; Louise T Day
Journal:  BMC Pregnancy Childbirth       Date:  2021-03-26       Impact factor: 3.007
  2 in total

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