Literature DB >> 2841645

Analysis of methylation of a human X located gene which escapes X inactivation.

C Mondello1, P J Goodfellow, P N Goodfellow.   

Abstract

The gene MIC2 is located in the pseudoautosomal region at the ends of the short arms of the X and Y chromosomes. In females MIC2 escapes X inactivation. We have analyzed the methylation pattern of MIC2 on the active X, the inactive X chromosomes, and the Y chromosome. The 5' end of the gene contains a GC rich region which is unmethylated on the active X, the inactive X and on the Y. The body of the gene is characterized by variable methylation.

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Year:  1988        PMID： 2841645      PMCID： PMC338335          DOI： 10.1093/nar/16.14.6813

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  14 in total

Review 1.  CpG-rich islands and the function of DNA methylation.

Authors:  A P Bird
Journal:  Nature       Date:  1986 May 15-21       Impact factor: 49.962

Review 2.  X-chromosome inactivation and developmental patterns in mammals.

Authors:  M F Lyon
Journal:  Biol Rev Camb Philos Soc       Date:  1972-01

3.  A human X-linked antigen defined by a monoclonal antibody.

Authors:  P Goodfellow; G Banting; R Levy; S Povey; A McMichael
Journal:  Somatic Cell Genet       Date:  1980-11

4.  Stability of DNA methylation of the human hypoxanthine phosphoribosyltransferase gene.

Authors:  P H Yen; T Mohandas; L J Shapiro
Journal:  Somat Cell Mol Genet       Date:  1986-03

5.  Differential methylation of hypoxanthine phosphoribosyltransferase genes on active and inactive human X chromosomes.

Authors:  P H Yen; P Patel; A C Chinault; T Mohandas; L J Shapiro
Journal:  Proc Natl Acad Sci U S A       Date:  1984-03       Impact factor: 11.205

6.  Reactivation of an inactive human X chromosome: evidence for X inactivation by DNA methylation.

Authors:  T Mohandas; R S Sparkes; L J Shapiro
Journal:  Science       Date:  1981-01-23       Impact factor: 47.728

7.  Non-inactivation of an x-chromosome locus in man.

Authors:  L J Shapiro; T Mohandas; R Weiss; G Romeo
Journal:  Science       Date:  1979-06-15       Impact factor: 47.728

8.  Transformation with DNA from 5-azacytidine-reactivated X chromosomes.

Authors:  L Venolia; S M Gartler; E R Wassman; P Yen; T Mohandas; L J Shapiro
Journal:  Proc Natl Acad Sci U S A       Date:  1982-04       Impact factor: 11.205

9.  Cloning an expressed gene shared by the human sex chromosomes.

Authors:  S M Darling; G S Banting; B Pym; J Wolfe; P N Goodfellow
Journal:  Proc Natl Acad Sci U S A       Date:  1986-01       Impact factor: 11.205

10.  Expression of the G6PD locus on the human X chromosome is associated with demethylation of three CpG islands within 100 kb of DNA.

Authors:  D Toniolo; G Martini; B R Migeon; R Dono
Journal:  EMBO J       Date:  1988-02       Impact factor: 11.598
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  4 in total

1.  Pulse-field linkage of the P3, G6pd and Cf-8 genes on the mouse X chromosome: demonstration of synteny at the physical level.

Authors:  N Brockdorff; L C Amar; S D Brown
Journal:  Nucleic Acids Res       Date:  1989-02-25       Impact factor: 16.971

Review 2.  DNA methylation. The effect of minor bases on DNA-protein interactions.

Authors:  R L Adams
Journal:  Biochem J       Date:  1990-01-15       Impact factor: 3.857

3.  DNA methylation of the X chromosomes of the human female: an in situ semi-quantitative analysis.

Authors:  J Bernardino; E Lamoliatte; M Lombard; A Niveleau; B Malfoy; B Dutrillaux; C A Bourgeois
Journal:  Chromosoma       Date:  1996-04       Impact factor: 4.316

4.  Induction of XIST expression from the human active X chromosome in mouse/human somatic cell hybrids by DNA demethylation.

Authors:  A V Tinker; C J Brown
Journal:  Nucleic Acids Res       Date:  1998-06-15       Impact factor: 16.971
  4 in total

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