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Literature DB >> 2841153

A novel superfamily of nucleoside triphosphate-binding motif containing proteins which are probably involved in duplex unwinding in DNA and RNA replication and recombination.

A E Gorbalenya¹, E V Koonin, A P Donchenko, V M Blinov.

Abstract

A statistically significant similarity was demonstrated between the amino acid sequences of 4 Escherichia coli helicases and helicase subunits, a family of non-structural proteins of eukaryotic positive-strand RNA viruses and 2 herpesvirus proteins all of which contain an NTP-binding sequence motif. Based on sequence analysis and secondary structure predictions, a generalized structural model for the ATP-binding core is proposed. It is suggested that all these proteins constitute a superfamily of helicases (or helicase subunits) involved in NTP-dependent duplex unwinding during DNA and RNA replication and recombination.

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Year: 1988 PMID： 2841153 PMCID： PMC7130140 DOI： 10.1016/0014-5793(88)81226-2

Source DB: PubMed Journal: FEBS Lett ISSN： 0014-5793 Impact factor: 4.124

37 in total

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Authors: K Takkinen
Journal: Nucleic Acids Res Date: 1986-07-25 Impact factor: 16.971

2. Theory of protein secondary structure and algorithm of its prediction.

Authors: O B Ptitsyn; A V Finkelstein
Journal: Biopolymers Date: 1983-01 Impact factor: 2.505

3. Consensus topography in the ATP binding site of the simian virus 40 and polyomavirus large tumor antigens.

Authors: M K Bradley; T F Smith; R H Lathrop; D M Livingston; T A Webster
Journal: Proc Natl Acad Sci U S A Date: 1987-06 Impact factor: 11.205

4. The complete DNA sequence of varicella-zoster virus.

Authors: A J Davison; J E Scott
Journal: J Gen Virol Date: 1986-09 Impact factor: 3.891

5. Complete nucleotide sequence of the Escherichia coli recB gene.

Authors: P W Finch; A Storey; K E Chapman; K Brown; I D Hickson; P T Emmerson
Journal: Nucleic Acids Res Date: 1986-11-11 Impact factor: 16.971

6. Nucleotide sequence of the brome mosaic virus genome and its implications for viral replication.

Authors: P Ahlquist; R Dasgupta; P Kaesberg
Journal: J Mol Biol Date: 1984-02-05 Impact factor: 5.469

7. The recBC deoxyribonuclease of Escherichia coli: isolation and characterization of the subunit proteins and reconstitution of the enzyme.

Authors: R P Lieberman; M Oishi
Journal: Proc Natl Acad Sci U S A Date: 1974-12 Impact factor: 11.205

8. Photoaffinity labeling of a viral induced protein from tobacco. Characterization of nucleotide-binding properties.

Authors: R K Evans; B E Haley; D A Roth
Journal: J Biol Chem Date: 1985-06-25 Impact factor: 5.157

Review 9. A novel superfamily of nucleoside triphosphate-binding motif containing proteins which are probably involved in duplex unwinding in DNA and RNA replication and recombination.

Authors: A E Gorbalenya; E V Koonin; A P Donchenko; V M Blinov
Journal: FEBS Lett Date: 1988-08-01 Impact factor: 4.124

109 in total

1. A region near the C-terminal end of Escherichia coli DNA helicase II is required for single-stranded DNA binding.

Authors: L E Mechanic; M E Latta; S W Matson
Journal: J Bacteriol Date: 1999-04 Impact factor: 3.490

2. Biochemical characterization of the equine arteritis virus helicase suggests a close functional relationship between arterivirus and coronavirus helicases.

Authors: A Seybert; L C van Dinten; E J Snijder; J Ziebuhr
Journal: J Virol Date: 2000-10 Impact factor: 5.103

3. Mtt1 is a Upf1-like helicase that interacts with the translation termination factors and whose overexpression can modulate termination efficiency.

Authors: K Czaplinski; N Majlesi; T Banerjee; S W Peltz
Journal: RNA Date: 2000-05 Impact factor: 4.942

4. The conserved helicase motifs of the herpes simplex virus type 1 origin-binding protein UL9 are important for function.

Authors: R Martinez; L Shao; S K Weller
Journal: J Virol Date: 1992-11 Impact factor: 5.103

5. Alteration by site-directed mutagenesis of the conserved lysine residue in the consensus ATP-binding sequence of the RecB protein of Escherichia coli.

Authors: S Hsieh; D A Julin
Journal: Nucleic Acids Res Date: 1992-11-11 Impact factor: 16.971