Literature DB >> 28409748

A Critical Assessment of Research on Neurotransmitters in Alzheimer's Disease.

P Hemachandra Reddy1,2,3,4,5,6,7.   

Abstract

The purpose of this mini-forum, "Neurotransmitters and Alzheimer's Disease", is to critically assess the current status of neurotransmitters in Alzheimer's disease. Neurotransmitters are essential neurochemicals that maintain synaptic and cognitive functions in mammals, including humans, by sending signals across pre- to post-synaptic neurons. Authorities in the fields of synapses and neurotransmitters of Alzheimer's disease summarize the current status of basic biology of synapses and neurotransmitters, and also update the current status of clinical trials of neurotransmitters in Alzheimer's disease. This article discusses the prevalence, economic impact, and stages of Alzheimer's dementia in humans.

Entities:  

Keywords:  Amyloid-β; cognitive decline; mitochondrial dysfunction; synaptic pathology

Mesh：

Substances：

Year:  2017        PMID： 28409748      PMCID： PMC5791142          DOI： 10.3233/JAD-170256

Source DB:  PubMed          Journal:  J Alzheimers Dis        ISSN： 1387-2877            Impact factor:   4.472


  22 in total

Review 1.  Mapping cellular transcriptosomes in autopsied Alzheimer's disease subjects and relevant animal models.

Authors:  P Hemachandra Reddy; Shannon McWeeney
Journal:  Neurobiol Aging       Date:  2005-09-12       Impact factor: 4.673

2.  Self assembly of microtubule associated protein tau into filaments resembling those found in Alzheimer disease.

Authors:  E Montejo de Garcini; L Serrano; J Avila
Journal:  Biochem Biophys Res Commun       Date:  1986-12-15       Impact factor: 3.575

Review 3.  Tau protein, the main component of paired helical filaments.

Authors:  Jesús Avila
Journal:  J Alzheimers Dis       Date:  2006       Impact factor: 4.472

Review 4.  Checks and balances on cholinergic signaling in brain and body function.

Authors:  Hermona Soreq
Journal:  Trends Neurosci       Date:  2015-06-20       Impact factor: 13.837

5.  Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein.

Authors:  G G Glenner; C W Wong
Journal:  Biochem Biophys Res Commun       Date:  1984-05-16       Impact factor: 3.575

Review 6.  Role of Glutamate and NMDA Receptors in Alzheimer's Disease.

Authors:  Rui Wang; P Hemachandra Reddy
Journal:  J Alzheimers Dis       Date:  2017       Impact factor: 4.472

Review 7.  How Studies of the Serotonin System in Macaque Models of Menopause Relate to Alzheimer's Disease1.

Authors:  Cynthia L Bethea; Arubala P Reddy; Fernanda Lima Christian
Journal:  J Alzheimers Dis       Date:  2017       Impact factor: 4.472

Review 8.  Intracellular amyloid-beta in Alzheimer's disease.

Authors:  Frank M LaFerla; Kim N Green; Salvatore Oddo
Journal:  Nat Rev Neurosci       Date:  2007-07       Impact factor: 34.870

Review 9.  Dynamics of the Complement, Cytokine, and Chemokine Systems in the Regulation of Synaptic Function and Dysfunction Relevant to Alzheimer's Disease.

Authors:  Shanya Jiang; Kiran Bhaskar
Journal:  J Alzheimers Dis       Date:  2017       Impact factor: 4.472

Review 10.  The amyloid hypothesis of Alzheimer's disease at 25 years.

Authors:  Dennis J Selkoe; John Hardy
Journal:  EMBO Mol Med       Date:  2016-06-01       Impact factor: 12.137
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  7 in total

1.  Sarcococca saligna ameliorated D-galactose induced neurodegeneration through repression of neurodegenerative and oxidative stress biomarkers.

Authors:  Uzma Saleem; Zunera Chauhdary; Sumera Islam; Aimen Zafar; Rana O Khayat; Norah A Althobaiti; Ghulam Mujtaba Shah; Mohammed Alqarni; Muhammad Ajmal Shah
Journal:  Metab Brain Dis       Date:  2022-07-26       Impact factor: 3.655

2.  Neuronal ER-Signalosome Proteins as Early Biomarkers in Prodromal Alzheimer's Disease Independent of Amyloid-β Production and Tau Phosphorylation.

Authors:  Fátima Mesa-Herrera; Raquel Marín; Eduardo Torrealba; Guido Santos; Mario Díaz
Journal:  Front Mol Neurosci       Date:  2022-05-05       Impact factor: 6.261

3.  Downregulation of PIK3CB Involved in Alzheimer's Disease via Apoptosis, Axon Guidance, and FoxO Signaling Pathway.

Authors:  Zhike Zhou; Jun Bai; Shanshan Zhong; Rongwei Zhang; Kexin Kang; Xiaoqian Zhang; Ying Xu; Chuansheng Zhao; Mei Zhao
Journal:  Oxid Med Cell Longev       Date:  2022-01-20       Impact factor: 6.543

4.  The Role of Oxidant-Antioxidant Status in Suicide Behavior in Kurdish Ethnicity.

Authors:  Mahin Oshnokhah; Maryam Bagheri; Hori Ghaneialvar; Karimeh Haghani; Ali Khorshidi; Ali Shahbazi; Sajjad Salari
Journal:  Basic Clin Neurosci       Date:  2021-09-01

Review 5.  Epigenetic Peripheral Biomarkers for Early Diagnosis of Alzheimer's Disease.

Authors:  Chiara Villa; Andrea Stoccoro
Journal:  Genes (Basel)       Date:  2022-07-22       Impact factor: 4.141

Review 6.  Regulation of Melatonin and Neurotransmission in Alzheimer's Disease.

Authors:  Jaydeep Roy; Ka Chun Tsui; Jonah Ng; Man-Lung Fung; Lee Wei Lim
Journal:  Int J Mol Sci       Date:  2021-06-25       Impact factor: 5.923

Review 7.  Missing lnc(RNAs) in Alzheimer's Disease?

Authors:  Rafaela Policarpo; Constantin d'Ydewalle
Journal:  Genes (Basel)       Date:  2021-12-23       Impact factor: 4.096
  7 in total

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