Literature DB >> 28375077

OCD: obsessive-compulsive … disgust? The role of disgust in obsessive-compulsive disorder.

Tracy Bhikram1, Elia Abi-Jaoude1, Paul Sandor1.   

Abstract

Recent research has identified the important role of disgust in the symptomatology of obsessive-compulsive disorder (OCD). Exaggerated and inappropriate disgust reactions may drive some of the symptoms of OCD, and in some cases, may even eclipse feelings of anxiety. This paper reviews behavioural and neuroimaging research that recognizes the prominent role of disgust in contributing to OCD symptoms, especially contamination-based symptoms. We discuss how elevated behavioural and biological markers of disgust reported in OCD populations support the need for alternative clinical treatment strategies and theoretical models of OCD.

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Year:  2017        PMID： 28375077      PMCID： PMC5573572          DOI： 10.1503/jpn.160079

Source DB:  PubMed          Journal:  J Psychiatry Neurosci        ISSN： 1180-4882            Impact factor:   6.186


  63 in total

1.  Both of us disgusted in My insula: the common neural basis of seeing and feeling disgust.

Authors:  Bruno Wicker; Christian Keysers; Jane Plailly; Jean Pierre Royet; Vittorio Gallese; Giacomo Rizzolatti
Journal:  Neuron       Date:  2003-10-30       Impact factor: 17.173

2.  Impairment of recognition of disgust in Chinese with Huntington's or Wilson's disease.

Authors:  Kai Wang; Rumjahn Hoosain; Ren-Min Yang; Yu Meng; Chang-Qing Wang
Journal:  Neuropsychologia       Date:  2003       Impact factor: 3.139

3.  The relationship between disgust sensitivity, anxiety and obsessions.

Authors:  S J Thorpe; S P Patel; L M Simonds
Journal:  Behav Res Ther       Date:  2003-12

4.  Localized orbitofrontal and subcortical metabolic changes and predictors of response to paroxetine treatment in obsessive-compulsive disorder.

Authors:  S Saxena; A L Brody; K M Maidment; J J Dunkin; M Colgan; S Alborzian; M E Phelps; L R Baxter
Journal:  Neuropsychopharmacology       Date:  1999-12       Impact factor: 7.853

5.  fMRI of neuronal activation with symptom provocation in unmedicated patients with obsessive compulsive disorder.

Authors:  C M Adler; P McDonough-Ryan; K W Sax; S K Holland; S Arndt; S M Strakowski
Journal:  J Psychiatr Res       Date:  2000 Jul-Oct       Impact factor: 4.791

Review 6.  The psychobiology of obsessive-compulsive disorder: how important is the role of disgust?

Authors:  D J Stein; Y Liu; N A Shapira; W K Goodman
Journal:  Curr Psychiatry Rep       Date:  2001-08       Impact factor: 5.285

7.  Facial expression recognition in people with medicated and unmedicated Parkinson's disease.

Authors:  R Sprengelmeyer; A W Young; K Mahn; U Schroeder; D Woitalla; T Büttner; W Kuhn; H Przuntek
Journal:  Neuropsychologia       Date:  2003       Impact factor: 3.139

8.  Brain glucose metabolic changes associated with neuropsychological improvements after 4 months of treatment in patients with obsessive-compulsive disorder.

Authors:  D-H Kang; J S Kwon; J-J Kim; T Youn; H-J Park; M S Kim; D S Lee; M C Lee
Journal:  Acta Psychiatr Scand       Date:  2003-04       Impact factor: 6.392

9.  Brain activation by disgust-inducing pictures in obsessive-compulsive disorder.

Authors:  Nathan A Shapira; Yijun Liu; Alex G He; Margaret M Bradley; Mary C Lessig; George A James; Dan J Stein; Peter J Lang; Wayne K Goodman
Journal:  Biol Psychiatry       Date:  2003-10-01       Impact factor: 13.382

10.  fMRI of emotional responses to odors: influence of hedonic valence and judgment, handedness, and gender.

Authors:  Jean-P Royet; Jane Plailly; Chantal Delon-Martin; David A Kareken; Christoph Segebarth
Journal:  Neuroimage       Date:  2003-10       Impact factor: 6.556
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  10 in total

1.  Gut Barrier Dysfunction and Type 2 Immunity: Implications for Compulsive Behavior.

Authors:  Christopher T Fields; Benoit Chassaing; Geert J de Vries
Journal:  Med Hypotheses       Date:  2022-02-14       Impact factor: 4.411

2.  Anti-Disgust Cognitive Behavioral Therapy for Contamination-Based Obsessive Compulsive Disorder: A Randomized Controlled Clinical Trial.

Authors:  Behzad Salmani; Francesco Mancini; Jafar Hasani; Zahra Zanjani
Journal:  J Clin Med       Date:  2022-05-19       Impact factor: 4.964

3.  An implicit priming intervention alters brain and behavioral responses to high-calorie foods: a randomized controlled study.

Authors:  Kristina T Legget; Marc-Andre Cornier; Christina Erpelding; Benjamin P Lawful; Joshua J Bear; Eugene Kronberg; Jason R Tregellas
Journal:  Am J Clin Nutr       Date:  2022-04-01       Impact factor: 8.472

4.  Neural correlates of symptom provocation in pediatric obsessive-compulsive disorder.

Authors:  Fern Jaspers-Fayer; Sarah Yao Lin; Elaine Chan; Rhonda Ellwyn; Ryan Lim; John Best; Laura Belschner; Donna Lang; Manraj K M Heran; Todd S Woodward; S Evelyn Stewart
Journal:  Neuroimage Clin       Date:  2019-10-23       Impact factor: 4.881

5.  Functional Connectivity within the Frontal-Striatal Network Differentiates Checkers from Washers of Obsessive-Compulsive Disorder.

Authors:  Jianping Yu; Minyao Xie; Shasha Song; Ping Zhou; Fangzheng Yuan; Mengyuan Ouyang; Chun Wang; Na Liu; Ning Zhang
Journal:  Brain Sci       Date:  2022-07-28

6.  Granisetron-mediated augmentation of sertraline therapeutic effect in obsessive-compulsive disorder: a double-blind placebo-controlled, randomized clinical trial.

Authors:  Ala Ghobadian; Saba Mokhtari; Behnam Shariati; Leila Kamalzadeh; Mohsen Shati; Mehrdad Eftekhar Ardebili; Masoomeh Yarahmadi; Mohammadreza Shalbafan
Journal:  BMC Pharmacol Toxicol       Date:  2022-09-27       Impact factor: 2.605

7.  The impact of the coronavirus (COVID-19) pandemic on the development of obsessive-compulsive symptoms in Saudi Arabia.

Authors:  Deemah A Alateeq; Haneen N Almughera; Tharaa N Almughera; Raghad F Alfedeah; Taeef S Nasser; Khozama A Alaraj
Journal:  Saudi Med J       Date:  2021-07       Impact factor: 1.422

8.  Examining the functional activity of different obsessive-compulsive symptom dimensions in Tourette syndrome.

Authors:  Tracy Bhikram; Adrian Crawley; Paul Arnold; Elia Abi-Jaoude; Paul Sandor
Journal:  Neuroimage Clin       Date:  2020-01-25       Impact factor: 4.881

9.  Imagery Rescripting on Guilt-Inducing Memories in OCD: A Single Case Series Study.

Authors:  Katia Tenore; Barbara Basile; Teresa Cosentino; Brunetto De Sanctis; Stefania Fadda; Giuseppe Femia; Andrea Gragnani; Olga I Luppino; Valerio Pellegrini; Claudia Perdighe; Giuseppe Romano; Angelo M Saliani; Francesco Mancini
Journal:  Front Psychiatry       Date:  2020-09-30       Impact factor: 4.157

10.  Contamination and infection: What the coronavirus pandemic could reveal about the evolutionary origins of obsessive-compulsive disorder.

Authors:  Ravi Philip Rajkumar
Journal:  Psychiatry Res       Date:  2020-05-05       Impact factor: 11.225
  10 in total

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