Literature DB >> 28371639

Anticancer activity of a series of copper(II) complexes with tripodal ligands.

Melanie Jopp1, Jonathan Becker1, Sabine Becker1, Andreas Miska1, Valentina Gandin2, Cristina Marzano3, Siegfried Schindler4.   

Abstract

A series of copper(II) complexes with tripodal polypyridylamine ligands (derived from the parent ligand tris(2-pyridylmethyl)amine, tmpa) has been synthesized. Crystallographic characterization was possible for all complexes obtained. The copper(II) chloride complexes were investigated for their in vitro anticancer potential using human tumor cell lines containing examples of cervical, colon, ovarian cancers and melanoma. Some compounds showed a similar activity compared to that of cisplatin, however no systematic behavior could be observed.
Copyright © 2017 Elsevier Masson SAS. All rights reserved.

Entities:  

Keywords:  Amine donor atoms; Anti tumor; Copper complexes; Cytotoxicity; Tripodal ligands

Mesh：

Substances：

Year:  2017        PMID： 28371639     DOI： 10.1016/j.ejmech.2017.03.019

Source DB:  PubMed          Journal:  Eur J Med Chem        ISSN： 0223-5234            Impact factor:   6.514


  8 in total

1.  Tetramethyl-phenanthroline copper complexes in the development of drugs to treat cancer: synthesis, characterization and cytotoxicity studies of a series of copper(II)-L-dipeptide-3,4,7,8-tetramethyl-phenanthroline complexes.

Authors:  Natalia Alvarez; Celisnolia M Leite; Adriana Napoleone; Luis F S Mendes; Carlos Y Fernández; Ronny R Ribeiro; Javier Ellena; Alzir A Batista; Antonio J Costa-Filho; Gianella Facchin
Journal:  J Biol Inorg Chem       Date:  2022-05-07       Impact factor: 3.862

2.  Anticancer activity, DNA binding and cell mechanistic studies of estrogen-functionalised Cu(II) complexes.

Authors:  Stephen Barrett; Michele De Franco; Andrew Kellett; Eithne Dempsey; Cristina Marzano; Andrea Erxleben; Valentina Gandin; Diego Montagner
Journal:  J Biol Inorg Chem       Date:  2019-10-26       Impact factor: 3.358

3.  Synthesis, Characterization, and Biological Evaluation of Unimetallic and Heterobimetallic Complexes of Bivalent Copper.

Authors:  Anshul Singh; Ashu Chaudhary
Journal:  Bioinorg Chem Appl       Date:  2018-04-12       Impact factor: 7.778

4.  Antiviral effect of copper chloride on feline calicivirus and synergy with ribavirin in vitro.

Authors:  Dengliang Li; Zhanding Cui; Guohua Li; Liangting Zhang; Ying Zhang; Han Zhao; Shuang Zhang; Yanbing Guo; Yanli Zhao; Fanxing Men; Shihui Zhao; Jiang Shao; Dongju Du; Hailong Huang; Kai Wang; Guixue Hu; Tiansong Li; Yongkun Zhao
Journal:  BMC Vet Res       Date:  2020-07-06       Impact factor: 2.741

5.  Five-Coordinated Geometries from Molecular Structures to Solutions in Copper(II) Complexes Generated from Polydentate-N-Donor Ligands and Pseudohalides.

Authors:  Franz A Mautner; Roland C Fischer; Ana Torvisco; Maher M Henary; Febee R Louka; Salah S Massoud; Nahed M H Salem
Journal:  Molecules       Date:  2020-07-25       Impact factor: 4.411

6.  Mapping the DNA Damaging Effects of Polypyridyl Copper Complexes with DNA Electrochemical Biosensors.

Authors:  Anna Banasiak; Nicolò Zuin Fantoni; Andrew Kellett; John Colleran
Journal:  Molecules       Date:  2022-01-19       Impact factor: 4.411

7.  Theoretical and experimental investigation of anticancer activities of an acyclic and symmetrical compartmental Schiff base ligand and its Co(ii), Cu(ii) and Zn(ii) complexes.

Authors:  Lotfali Saghatforoush; Keyvan Moeini; Seyed Abolfazl Hosseini-Yazdi; Zahra Mardani; Alireza Hajabbas-Farshchi; Heather T Jameson; Shane G Telfer; J Derek Woollins
Journal:  RSC Adv       Date:  2018-10-17       Impact factor: 4.036

8.  Solvent-driven structural topology involving energetically significant intra- and intermolecular chelate ring contacts and anticancer activities of Cu(ii) phenanthroline complexes involving benzoates: experimental and theoretical studies.

Authors:  Manjit K Bhattacharyya; Utpal Saha; Debajit Dutta; Amal Das; Akalesh K Verma; Antonio Frontera
Journal:  RSC Adv       Date:  2019-05-24       Impact factor: 4.036
  8 in total

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