Literature DB >> 28358379

Children's outcomes at 2-year follow-up after 4 years of structured multi-professional medical-ethical decision-making in a neonatal intensive care unit.

J C de Boer1, L Gennissen2, M Williams1, M van Dijk1,3, D Tibboel3, I Reiss1, S Naghib3, J Sol1,4.   

Abstract

OBJECTIVE: We reviewed our decisions about continuation/withdrawal of life-sustaining treatments in a group of critically ill newborns who were discussed in structured medical ethical decision-making meetings, and provide the surviving children's outcomes at 2-year follow-up. STUDY
DESIGN: In an explorative observational study, 61 cases were evaluated. The children involved had been discussed in such a structured way from 2009 to 2012 in a level III-D neonatal intensive care unit.
RESULTS: Decisions made were: full treatment (n=6), earlier restriction cancelled (n=3), treatment restriction (n=30) and palliative care (n=22). Parents of six children disagreed with the decision proposed. Thirteen (54%) of the 24 children who survived (39%) had moderate to severe neurological problems; 8 (33%) had additional sequelae; only one 2-year-old child was healthy.
CONCLUSIONS: Decisions made varied to a large extent. The poor outcomes should be disseminated among decision makers. Future studies must explore new ways to improve outcome prediction, extend follow-up periods and consider what living with severe handicaps really means for both child and family.

Entities:  

Mesh:

Year:  2017        PMID: 28358379     DOI: 10.1038/jp.2017.30

Source DB:  PubMed          Journal:  J Perinatol        ISSN: 0743-8346            Impact factor:   2.521


  22 in total

1.  Deciding on treatment limitation for neonates: the parents' perspective.

Authors:  H E McHaffie; A J Lyon; R Hume
Journal:  Eur J Pediatr       Date:  2001-06       Impact factor: 3.183

2.  CRIB II: an update of the clinical risk index for babies score.

Authors:  Gareth Parry; Janet Tucker; William Tarnow-Mordi
Journal:  Lancet       Date:  2003-05-24       Impact factor: 79.321

3.  The Groningen protocol--euthanasia in severely ill newborns.

Authors:  Eduard Verhagen; Pieter J J Sauer
Journal:  N Engl J Med       Date:  2005-03-10       Impact factor: 91.245

4.  The stability of the diagnosis of developmental disability between ages 2 and 8 in a geographic cohort of very preterm children born in 1997.

Authors:  G Roberts; P J Anderson; L W Doyle
Journal:  Arch Dis Child       Date:  2009-10-14       Impact factor: 3.791

Review 5.  Measuring and communicating meaningful outcomes in neonatology: A family perspective.

Authors:  Annie Janvier; Barbara Farlow; Jason Baardsnes; Rebecca Pearce; Keith J Barrington
Journal:  Semin Perinatol       Date:  2016-10-26       Impact factor: 3.300

6.  Parent Involvement in End-of-Life Care and Decision Making in the Newborn Intensive Care Unit: An Integrative Review.

Authors:  Lacey M Eden; Lynn Clark Callister
Journal:  J Perinat Educ       Date:  2010

7.  Creation of a neonatal end-of-life palliative care protocol.

Authors:  Anita Catlin; Brian Carter
Journal:  J Perinatol       Date:  2002 Apr-May       Impact factor: 2.521

8.  Deaths in a neonatal intensive care unit: a 10-year perspective.

Authors:  Cathrine Monrad Hagen; Thor Willy Ruud Hansen
Journal:  Pediatr Crit Care Med       Date:  2004-09       Impact factor: 3.624

9.  Clinical report--Forgoing medically provided nutrition and hydration in children.

Authors:  Douglas S Diekema; Jeffrey R Botkin
Journal:  Pediatrics       Date:  2009-07-27       Impact factor: 7.124

10.  End-of-life decision-making in six European countries: descriptive study.

Authors:  Agnes van der Heide; Luc Deliens; Karin Faisst; Tore Nilstun; Michael Norup; Eugenio Paci; Gerrit van der Wal; Paul J van der Maas
Journal:  Lancet       Date:  2003-08-02       Impact factor: 79.321

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