Literature DB >> 28316360

An Inverse Problem for a Class of Conditional Probability Measure-Dependent Evolution Equations.

Inom Mirzaev1, Erin C Byrne2, David M Bortz1.   

Abstract

We investigate the inverse problem of identifying a conditional probability measure in measure-dependent evolution equations arising in size-structured population modeling. We formulate the inverse problem as a least squares problem for the probability measure estimation. Using the Prohorov metric framework, we prove existence and consistency of the least squares estimates and outline a discretization scheme for approximating a conditional probability measure. For this scheme, we prove general method stability. The work is motivated by Partial Differential Equation (PDE) models of flocculation for which the shape of the post-fragmentation conditional probability measure greatly impacts the solution dynamics. To illustrate our methodology, we apply the theory to a particular PDE model that arises in the study of population dynamics for flocculating bacterial aggregates in suspension, and provide numerical evidence for the utility of the approach.

Entities:  

Keywords:  Conditional probability measures; bacterial aggregates; flocculation; fragmentation; inverse problem; measure-dependent evolution equations; size-structured populations

Year:  2016        PMID: 28316360      PMCID: PMC5352987          DOI: 10.1088/0266-5611/32/9/095005

Source DB:  PubMed          Journal:  Inverse Probl        ISSN: 0266-5611            Impact factor:   2.407


  15 in total

1.  Generalized sensitivity functions in physiological system identification.

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2.  Estimating the division rate for the growth-fragmentation equation.

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3.  Modeling and measurement of yeast flocculation.

Authors:  R H Davis; T P Hunt
Journal:  Biotechnol Prog       Date:  1986-06

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5.  Distributed parameter identification for a label-structured cell population dynamics model using CFSE histogram time-series data.

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Journal:  J Math Biol       Date:  2008-12-19       Impact factor: 2.259

6.  Systems biology. Conditional density-based analysis of T cell signaling in single-cell data.

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9.  Postfragmentation density function for bacterial aggregates in laminar flow.

Authors:  Erin Byrne; Steve Dzul; Michael Solomon; John Younger; David M Bortz
Journal:  Phys Rev E Stat Nonlin Soft Matter Phys       Date:  2011-04-15

10.  Numerical modelling of label-structured cell population growth using CFSE distribution data.

Authors:  Tatyana Luzyanina; Dirk Roose; Tim Schenkel; Martina Sester; Stephan Ehl; Andreas Meyerhans; Gennady Bocharov
Journal:  Theor Biol Med Model       Date:  2007-07-24       Impact factor: 2.432

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