Literature DB >> 28304032

Facile synthesis of chlorin bioconjugates by a series of click reactions.

Junior Gonzales1, N V S Dinesh K Bhupathiraju2, William Perea2, Huong Chu1, Naxhije Berisha2, Veronica Bueno2, Naser Dodic2, Julia Rozenberg2, Nancy L Greenbaum1, Charles Michael Drain3.   

Abstract

A multifunctional chlorin platform appended with four short polyethylene glycols and a carboxylate-linker allows rapid conjugation to biotargeting motifs such as proteins and oligonucleotides. The stability and photophysical properties of the chlorin enable development of diagnostics, imaging, molecular tracking, and theranostics.

Entities:  

Mesh：

Substances：

Year:  2017        PMID： 28304032      PMCID： PMC5463999          DOI： 10.1039/c7cc01265a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  15 in total

Review 1.  Glycosylated Porphyrins, Phthalocyanines, and Other Porphyrinoids for Diagnostics and Therapeutics.

Authors:  Sunaina Singh; Amit Aggarwal; N V S Dinesh K Bhupathiraju; Gianluca Arianna; Kirran Tiwari; Charles Michael Drain
Journal:  Chem Rev       Date:  2015-08-28       Impact factor: 60.622

Review 2.  Fluorinated porphyrinoids as efficient platforms for new photonic materials, sensors, and therapeutics.

Authors:  N V S Dinesh K Bhupathiraju; Waqar Rizvi; James D Batteas; Charles Michael Drain
Journal:  Org Biomol Chem       Date:  2016-01-14       Impact factor: 3.876

Review 3.  Basic principles, applications in oncology and improved selectivity of photodynamic therapy.

Authors:  Maarten B Vrouenraets; Gerard W M Visser; Gordon B Snow; Guus A M S van Dongen
Journal:  Anticancer Res       Date:  2003 Jan-Feb       Impact factor: 2.480

4.  1,3-Dioxopyrrolo[3,4-b]porphyrins: synthesis and chemistry.

Authors:  Carla M B Carvalho; Maria G P M S Neves; Augusto C Tomé; Filipe A Almeida Paz; Artur M S Silva; José A S Cavaleiro
Journal:  Org Lett       Date:  2010-12-03       Impact factor: 6.005

5.  1,3-dipolar cycloaddition reactions of porphyrins with azomethine ylides.

Authors:  Ana M G Silva; Augusto C Tomé; Maria G P M S Neves; Artur M S Silva; José A S Cavaleiro
Journal:  J Org Chem       Date:  2005-03-18       Impact factor: 4.354

6.  Synthesis and photophysical properties of thioglycosylated chlorins, isobacteriochlorins, and bacteriochlorins for bioimaging and diagnostics.

Authors:  Sunaina Singh; Amit Aggarwal; Sebastian Thompson; João P C Tomé; Xianchun Zhu; Diana Samaroo; Mikki Vinodu; Ruomei Gao; Charles Michael Drain
Journal:  Bioconjug Chem       Date:  2010-10-21       Impact factor: 4.774

Review 7.  Antibodies armed with photosensitizers: from chemical synthesis to photobiological applications.

Authors:  Patricia M R Pereira; Barbara Korsak; Bruno Sarmento; Rudolf J Schneider; Rosa Fernandes; João P C Tomé
Journal:  Org Biomol Chem       Date:  2015-03-07       Impact factor: 3.876

8.  Poly(ethylene glycol)-Prodrug Conjugates: Concept, Design, and Applications.

Authors:  Shashwat S Banerjee; Naval Aher; Rajesh Patil; Jayant Khandare
Journal:  J Drug Deliv       Date:  2012-05-07

9.  Phototoxic aptamers selectively enter and kill epithelial cancer cells.

Authors:  Cátia S M Ferreira; Melissa C Cheung; Sotiris Missailidis; Stuart Bisland; Jean Gariépy
Journal:  Nucleic Acids Res       Date:  2008-12-22       Impact factor: 16.971

10.  Porphyrins as theranostic agents from prehistoric to modern times.

Authors:  Yumiao Zhang; Jonathan F Lovell
Journal:  Theranostics       Date:  2012-09-30       Impact factor: 11.556
View more
  3 in total

1.  Bimodal Imaging of Mouse Peripheral Nerves with Chlorin Tracers.

Authors:  Junior Gonzales; Javier Hernández-Gil; Thomas C Wilson; Dauren Adilbay; Mike Cornejo; Paula Demétrio de Souza Franca; Navjot Guru; Christina I Schroeder; Glenn F King; Jason S Lewis; Thomas Reiner
Journal:  Mol Pharm       Date:  2021-01-06       Impact factor: 4.939

2.  Leveraging synthetic chlorins for bio-imaging applications.

Authors:  Javier Hernández-Gil; Jason S Lewis; Thomas Reiner; Charles Michael Drain; Junior Gonzales
Journal:  Chem Commun (Camb)       Date:  2020-10-20       Impact factor: 6.222

3.  Chlorophyll-Inspired Red-Region Fluorophores: Building Block Synthesis and Studies in Aqueous Media.

Authors:  Rui Liu; Mengran Liu; Don Hood; Chih-Yuan Chen; Christopher J MacNevin; Dewey Holten; Jonathan S Lindsey
Journal:  Molecules       Date:  2018-01-10       Impact factor: 4.411
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.