Literature DB >> 32945820

Leveraging synthetic chlorins for bio-imaging applications.

Javier Hernández-Gil1, Jason S Lewis2, Thomas Reiner3, Charles Michael Drain4, Junior Gonzales5.   

Abstract

Synthetic chlorins are not only fluorescent, the modulation of the tetrapyrrole system can also chelate metal ions. Conjugation of linkers at their pyrrolidines allows for conjugation to bio-molecules to create target specificity. By altering these chemo-photophysical properties, this work facilitates the use of chlorins in fluorescent imaging and positron emission tomography (PET).

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Year:  2020        PMID： 32945820      PMCID： PMC7907923          DOI： 10.1039/d0cc05494a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  17 in total

Review 1.  Fluorinated porphyrinoids as efficient platforms for new photonic materials, sensors, and therapeutics.

Authors:  N V S Dinesh K Bhupathiraju; Waqar Rizvi; James D Batteas; Charles Michael Drain
Journal:  Org Biomol Chem       Date:  2016-01-14       Impact factor: 3.876

2.  The potential for photodynamic therapy in the treatment of localized infections.

Authors:  Katie O'Riordan; Oleg E Akilov; Tayyaba Hasan
Journal:  Photodiagnosis Photodyn Ther       Date:  2005-10-27       Impact factor: 3.631

3.  Global priority multidrug-resistant pathogens do not resist photodynamic therapy.

Authors:  Caetano Padial Sabino; Mark Wainwright; Martha Simões Ribeiro; Fábio Parra Sellera; Carolina Dos Anjos; Mauricio da Silva Baptista; Nilton Lincopan
Journal:  J Photochem Photobiol B       Date:  2020-05-11       Impact factor: 6.252

4.  Potentiation of chlorin e6 photodynamic activity in vitro with peptide-based intracellular vehicles.

Authors:  S K Bisland; D Singh; J Gariépy
Journal:  Bioconjug Chem       Date:  1999 Nov-Dec       Impact factor: 4.774

5.  Antibody-targeted photolysis: in vitro studies with Sn(IV) chlorin e6 covalently bound to monoclonal antibodies using a modified dextran carrier.

Authors:  S L Rakestraw; R G Tompkins; M L Yarmush
Journal:  Proc Natl Acad Sci U S A       Date:  1990-06       Impact factor: 11.205

6.  Synthesis and photophysical properties of thioglycosylated chlorins, isobacteriochlorins, and bacteriochlorins for bioimaging and diagnostics.

Authors:  Sunaina Singh; Amit Aggarwal; Sebastian Thompson; João P C Tomé; Xianchun Zhu; Diana Samaroo; Mikki Vinodu; Ruomei Gao; Charles Michael Drain
Journal:  Bioconjug Chem       Date:  2010-10-21       Impact factor: 4.774

7.  Facile synthesis of chlorin bioconjugates by a series of click reactions.

Authors:  Junior Gonzales; N V S Dinesh K Bhupathiraju; William Perea; Huong Chu; Naxhije Berisha; Veronica Bueno; Naser Dodic; Julia Rozenberg; Nancy L Greenbaum; Charles Michael Drain
Journal:  Chem Commun (Camb)       Date:  2017-03-28       Impact factor: 6.222

8.  Transforming a Targeted Porphyrin Theranostic Agent into a PET Imaging Probe for Cancer.

Authors:  Jiyun Shi; Tracy W B Liu; Juan Chen; David Green; David Jaffray; Brian C Wilson; Fan Wang; Gang Zheng
Journal:  Theranostics       Date:  2011-09-15       Impact factor: 11.556

9.  Fluorescence labeling of a NaV1.7-targeted peptide for near-infrared nerve visualization.

Authors:  Junior Gonzales; Giacomo Pirovano; Chun Yuen Chow; Paula Demetrio de Souza Franca; Lukas M Carter; Julie K Klint; Navjot Guru; Jason S Lewis; Glenn F King; Thomas Reiner
Journal:  EJNMMI Res       Date:  2020-05-14       Impact factor: 3.138

10.  Porphyrins as theranostic agents from prehistoric to modern times.

Authors:  Yumiao Zhang; Jonathan F Lovell
Journal:  Theranostics       Date:  2012-09-30       Impact factor: 11.556
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  1 in total

1.  Bimodal Imaging of Mouse Peripheral Nerves with Chlorin Tracers.

Authors:  Junior Gonzales; Javier Hernández-Gil; Thomas C Wilson; Dauren Adilbay; Mike Cornejo; Paula Demétrio de Souza Franca; Navjot Guru; Christina I Schroeder; Glenn F King; Jason S Lewis; Thomas Reiner
Journal:  Mol Pharm       Date:  2021-01-06       Impact factor: 4.939
  1 in total

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