Literature DB >> 28298664

The Impact of Roller Pump vs. Centrifugal Pump on Homologous Blood Transfusion in Pediatric Cardiac Surgery.

Bharat Datt1, Moui B Nguyen1, Gary Plancher1, Mark Ruzmetov1, Michael O'Brien1, Alicia Kube1, Hamish M Munro1, Kamal K Pourmoghadam1, William M DeCampli1.   

Abstract

Centrifugal pumps are considered to be less destructive to blood elements (1) when compared to roller pumps. However, their large prime volumes render them unsuitable as arterial pumps in heart lung machine (HLM) circuitry for children. In November of 2014, the circuit at Arnold Palmer Hospital, a Biomedicus BP-50 with kinetic assist venous drainage (KAVD) and 1/4″ tubing was converted to a roller pump in the arterial position with gravity drainage. Vacuum-assisted venous drainage (VAVD) was mounted on the HLM as a backup, but not used. Tubing was changed to 3/16″ in the arterial line in patients <13 kg. A retrospective study with a total of 140 patients compared patients placed on cardiopulmonary bypass (CPB) with Biomedicus centrifugal pumps and KAVD (Centrifugal Group, n = 40) to those placed on CPB with roller pumps and gravity drainage (Roller Group, n = 100). Patients requiring extra-corporeal membrane oxygenation (ECMO)/cardio-pulmonary support (CPS) or undergoing a hybrid procedure were excluded. Re-operation or circulatory arrest patients were not excluded. Prime volumes decreased by 57% from 456 ± 34 mL in the Centrifugal Group to 197 ± 34 mL in the Roller Group (p < .001). There was a corresponding increase in hematocrit (HCT) of blood primes and also on CPB. Intraoperative homologous blood transfusions also decreased 55% from 422 mL in the Centrifugal Group to 231 mL in the Roller Group (p < .001). The Society of Thoracic Surgeons--European Association for Cardio-Thoracic Surgery (STAT) categorized intubation times and hospital length of stay (LOS) for all infants showed a trend toward reduction, but was not statistically significant. Overall mortality was 5% utilizing the centrifugal configuration and 0% in the roller pump cohort. We demonstrated that the transition to roller pumps in the arterial position of the HLM considerably reduced our priming volume and formed a basis for a comprehensive blood conservation program. By maintaining higher HCTs on CPB, we were able to reduce intraoperative homologous blood transfusions.

Entities:  

Keywords:  cardiopulmonary bypass; heart lung machine; kinetic assist venous drainage; modified ultra-filtration; vacuum-assisted venous drainage

Mesh:

Year:  2017        PMID: 28298664      PMCID: PMC5347217     

Source DB:  PubMed          Journal:  J Extra Corpor Technol        ISSN: 0022-1058


  16 in total

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Authors:  Alaina K Kipps; David Wypij; Ravi R Thiagarajan; Emile A Bacha; Jane W Newburger
Journal:  Pediatr Crit Care Med       Date:  2011-01       Impact factor: 3.624

2.  Transfusion-free complex cardiac surgery: with use of deep hypothermic circulatory arrest in a preterm 2.96-kg Jehovah's witness neonate.

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Journal:  Tex Heart Inst J       Date:  2011

3.  Transfusion-free complex cardiac surgery with cardiopulmonary bypass in a 3.55-kg Jehovah's Witness neonate.

Authors:  Michael Huebler; Wolfgang Boettcher; Andreas Koster; Michael Emeis; Peter Lange; Roland Hetzer
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4.  Assisted venous drainage cardiopulmonary bypass in congenital heart surgery.

Authors:  J W Ojito; R L Hannan; K Miyaji; J A White; T W McConaghey; J P Jacobs; R P Burke
Journal:  Ann Thorac Surg       Date:  2001-04       Impact factor: 4.330

5.  A single-center strategy to minimize blood transfusion in neonates and children undergoing cardiac surgery.

Authors:  Aymen N Naguib; Peter D Winch; Joseph D Tobias; Janet Simsic; Diane Hersey; Kathleen Nicol; Thomas Preston; Daniel Gomez; Patrick McConnell; Mark Galantowicz
Journal:  Paediatr Anaesth       Date:  2015-01-12       Impact factor: 2.556

6.  Blood transfusion determines postoperative morbidity in pediatric cardiac surgery applying a comprehensive blood-sparing approach.

Authors:  Matthias Redlin; Marian Kukucka; Wolfgang Boettcher; Helge Schoenfeld; Michael Huebler; Hermann Kuppe; Helmut Habazettl
Journal:  J Thorac Cardiovasc Surg       Date:  2012-12-08       Impact factor: 5.209

7.  Predictive factors for red blood cell transfusion in children undergoing noncomplex cardiac surgery.

Authors:  Muj Mulaj; David Faraoni; Ariane Willems; Cristel Sanchez Torres; Philippe Van der Linden
Journal:  Ann Thorac Surg       Date:  2014-06-24       Impact factor: 4.330

Review 8.  Coagulation disorders of cardiopulmonary bypass: a review.

Authors:  Domenico Paparella; Stephanie J Brister; Michael R Buchanan
Journal:  Intensive Care Med       Date:  2004-07-24       Impact factor: 17.440

9.  Perfusion technique for nonhaemic cardiopulmonary bypass prime in neonates and infants under 6 kg body weight.

Authors:  Frank Merkle; Wolfgang Boettcher; Fritz Schulz; Andreas Koster; Michael Huebler; Roland Hetzer
Journal:  Perfusion       Date:  2004-07       Impact factor: 1.972

10.  Transfusion-free cardiac reoperation in an 11-kg Jehovah's Witness child by use of a minimized cardiopulmonary bypass circuit.

Authors:  Michael Huebler; Wolfgang Boettcher; Andreas Koster; Brigitte Stiller; Hermann Kuppe; Roland Hetzer
Journal:  Tex Heart Inst J       Date:  2007
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  2 in total

1.  The effect of roller head pump on platelet deterioration during the simulated extracorporeal circulation.

Authors:  Tatsuya Furugaki; Osamu Shigeta; Yukinori Kozuma; Toru Tsukada; Tomomi Nakajima; Hiroaki Sakamoto; Bryan J Mathis; Yuji Hiramatsu; Yasuyuki Suzuki
Journal:  J Artif Organs       Date:  2020-07-04       Impact factor: 1.731

2.  The Novel Use of a Low Prime Modified Ultrafiltration Apparatus in a 13-kg Jehovah's Witness Patient: A Case Report.

Authors:  Bharat Datt; Hamish M Munro; William M DeCampli
Journal:  J Extra Corpor Technol       Date:  2018-09
  2 in total

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