Literature DB >> 25581204

A single-center strategy to minimize blood transfusion in neonates and children undergoing cardiac surgery.

Aymen N Naguib1, Peter D Winch, Joseph D Tobias, Janet Simsic, Diane Hersey, Kathleen Nicol, Thomas Preston, Daniel Gomez, Patrick McConnell, Mark Galantowicz.   

Abstract

BACKGROUND: The transfusion of blood products in the setting of uncontrolled bleeding is unquestionably lifesaving. However, in many instances, the decision to transfuse is based on physician gestalt rather than medical evidence. When indications for transfusion are unclear, the benefits of blood products must be balanced against their significant risks and associated costs. As our institution is a referral center for patients of Jehovah's Witness faith, this population has pushed our development of techniques to achieve the goal of bloodless surgery. Our practices in caring for this population have become our standard practice for managing all patients undergoing congenital cardiac surgery.
OBJECTIVES: To evaluate our success in minimizing the use of blood products during pediatric cardiac surgery.
METHODS: After IRB approval, we retrospectively reviewed all patients who underwent cardiac surgery utilizing cardiopulmonary bypass (CPB), for biventricular repair procedures. The study was conducted at a single institution (Nationwide Children's Hospital (NCH)) during the period: January 1, 2013 and December 31, 2013.
RESULTS: A total of 209 patients were included. Overall, 81 patients (38.8%) and 81 of 136 (59.6%) weighing more than 6 kg received no blood products (bloodless) during their entire hospital stay. Bloodless surgery was most successful in patients weighing more than 18 kg, followed by patients weighing 6-18 kg. All 73 patients who weighed <6 kg received blood transfusion during their hospitalization.
CONCLUSION: The techniques that we have developed to initially care for our Jehovah's Witness families may be applied to other pediatric and adult surgical procedures.
© 2015 John Wiley & Sons Ltd.

Entities:  

Keywords:  adverse; blood transfusion - hematology; congenital heart disease - cardiac; events - complications; infant - age; neonate - age

Mesh:

Year:  2015        PMID: 25581204     DOI: 10.1111/pan.12604

Source DB:  PubMed          Journal:  Paediatr Anaesth        ISSN: 1155-5645            Impact factor:   2.556


  6 in total

1.  The Impact of Roller Pump vs. Centrifugal Pump on Homologous Blood Transfusion in Pediatric Cardiac Surgery.

Authors:  Bharat Datt; Moui B Nguyen; Gary Plancher; Mark Ruzmetov; Michael O'Brien; Alicia Kube; Hamish M Munro; Kamal K Pourmoghadam; William M DeCampli
Journal:  J Extra Corpor Technol       Date:  2017-03

2.  Perioperative Management of a Child with Hypoplastic Left Heart Syndrome of the Jehovah's Witness Faith Presenting for Hybrid Comprehensive Stage II Procedure.

Authors:  Sathappan Karuppiah; Christopher Mckee; Ashley Hodge; Mark Galantowicz; Joseph Tobias; Aymen Naguib
Journal:  J Extra Corpor Technol       Date:  2016-09

3.  The Novel Use of a Low Prime Modified Ultrafiltration Apparatus in a 13-kg Jehovah's Witness Patient: A Case Report.

Authors:  Bharat Datt; Hamish M Munro; William M DeCampli
Journal:  J Extra Corpor Technol       Date:  2018-09

4.  The Effect of Autologus Blood Priming on Cerebral Oximetry in Congenital Cardiac Surgery Patients.

Authors:  Ashley Hodge; Apryl Cohen; Peter Winch; Dmitry Tumin; Jeffrey Burnside; Todd Ratliff; Mark Galantowicz; Aymen Naguib
Journal:  J Extra Corpor Technol       Date:  2017-09

5.  Changes in Transfusion Practice in Children and Adolescents over Time.

Authors:  Florian Piekarski; Andrea Steinbicker; Kai Zacharowski; Patrick Meybohm
Journal:  Transfus Med Hemother       Date:  2020-09-16       Impact factor: 3.747

6.  Attempting to Honor Beliefs of Jehovah's Witnesses at the Edge of Viability in an Infant Born at 23 Weeks' Gestational Age.

Authors:  Charles W Sauer; Krishelle L Marc-Aurele
Journal:  Am J Case Rep       Date:  2016-06-03
  6 in total

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