Literature DB >> 28283917

Risk Perception and Psychological Distress in Genetic Counselling for Hereditary Breast and/or Ovarian Cancer.

G Cicero1, R De Luca2, P Dorangricchia2, G Lo Coco3, C Guarnaccia4, D Fanale2, V Calò2, A Russo2.   

Abstract

Oncological Genetic Counselling (CGO) allows the identification of a genetic component that increases the risk of developing a cancer. Individuals' psychological reactions are influenced by both the content of the received information and the subjective perception of their own risk of becoming ill or being a carrier of a genetic mutation. This study included 120 participants who underwent genetic counselling for breast and/or ovarian cancer. The aim of the study was to examine the relation between their cancer risk perception and the genetic risk during CGO before receiving genetic test results, considering the influence of some psychological variables, in particular distress, anxiety and depression. Participants completed the following tools during a psychological interview: a socio-demographic form, Cancer Risk Perception (CRP) and Genetic Risk Perception (GRP), Hospital Anxiety and Depression Scale (HADS) and Distress Thermometer (DT). The data seem to confirm our hypothesis. Positive and significant correlations were found between the observed variables. Moreover, genetic risk perception determined an increase in depressive symptomatology and cancer risk perception led to an increase in anxious symptomatology, specifically in participants during cancer treatment. The present results suggest the importance of assessing genetic and cancer risk perception in individuals who undergo CGO, to identify those who are at risk of a decrease in psychological well-being and of developing greater psychological distress.

Entities:  

Keywords:  BRCA 1/2; Cancer risk perception; Distress; Genetic counselling; Genetic risk perception

Mesh:

Year:  2017        PMID: 28283917     DOI: 10.1007/s10897-017-0072-0

Source DB:  PubMed          Journal:  J Genet Couns        ISSN: 1059-7700            Impact factor:   2.537


  34 in total

1.  A new definition of Genetic Counseling: National Society of Genetic Counselors' Task Force report.

Authors:  Robert Resta; Barbara Bowles Biesecker; Robin L Bennett; Sandra Blum; Susan Estabrooks Hahn; Michelle N Strecker; Janet L Williams
Journal:  J Genet Couns       Date:  2006-04       Impact factor: 2.537

Review 2.  Psychological impact of genetic testing for cancer susceptibility: an update of the literature.

Authors:  Bettina Meiser
Journal:  Psychooncology       Date:  2005-12       Impact factor: 3.894

3.  Cognitive and psychological impact of BRCA genetic counseling in before and after definitive surgery breast cancer patients.

Authors:  Juliette Christie; Gwendolyn P Quinn; Teri Malo; Ji-Hyun Lee; Xiuhua Zhao; Jessica McIntyre; Jennifer Brzosowicz; Paul B Jacobsen; Susan T Vadaparampil
Journal:  Ann Surg Oncol       Date:  2012-07-06       Impact factor: 5.344

4.  Improved health perception after genetic counselling for women at high risk of breast and/or ovarian cancer: construction of new questionnaires--an Italian exploratory study.

Authors:  Chiara Catania; Irene Feroce; Monica Barile; Aron Goldhirsch; Tommaso De Pas; Filippo de Braud; Sabrina Boselli; Laura Adamoli; Davide Radice; Alessandra Rossi; Gianluca Spitaleri; Cristina Noberasco; Bernardo Bonanni
Journal:  J Cancer Res Clin Oncol       Date:  2015-11-17       Impact factor: 4.553

5.  The impact of genetic counseling on knowledge and emotional responses in Spanish population with family history of breast cancer.

Authors:  Esther Cabrera; Ignacio Blanco; Carmen Yagüe; Adelaida Zabalegui
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Review 6.  Improving subjective perception of personal cancer risk: systematic review and meta-analysis of educational interventions for people with cancer or at high risk of cancer.

Authors:  Mbathio Dieng; Caroline G Watts; Nadine A Kasparian; Rachael L Morton; Graham J Mann; Anne E Cust
Journal:  Psychooncology       Date:  2014-01-14       Impact factor: 3.894

Review 7.  Psychological impact of genetic counseling for familial cancer: a systematic review and meta-analysis.

Authors:  Dejana Braithwaite; Jon Emery; Fiona Walter; A Toby Prevost; Stephen Sutton
Journal:  Fam Cancer       Date:  2006       Impact factor: 2.375

8.  Intentions for risk-reducing surgery among high-risk women referred for BRCA1/BRCA2 genetic counseling.

Authors:  Angie Tong; Scott Kelly; Rachel Nusbaum; Kristi Graves; Beth N Peshkin; Heiddis B Valdimarsdottir; Marie Wood; Wendy McKinnon; Judy Garber; Shelley R McCormick; Lina Jandorf; Marc D Schwartz
Journal:  Psychooncology       Date:  2014-05-17       Impact factor: 3.894

Review 9.  A systematic review of perceived risks, psychological and behavioral impacts of genetic testing.

Authors:  Jodi T Heshka; Crystal Palleschi; Heather Howley; Brenda Wilson; Philip S Wells
Journal:  Genet Med       Date:  2008-01       Impact factor: 8.822

10.  Cancer genetic counseling: communication and counselees' post-visit satisfaction, cognitions, anxiety, and needs fulfillment.

Authors:  Arwen H Pieterse; Alexandra M van Dulmen; Frits A Beemer; Jozien M Bensing; Margreet G E M Ausems
Journal:  J Genet Couns       Date:  2007-02-13       Impact factor: 2.537

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  11 in total

1.  Cost-effectiveness evaluation of pre-counseling telephone interviews before face-to-face genetic counseling in cancer genetics.

Authors:  Gaëlle Collet; Nathalie Parodi; Kevin Cassinari; Zoe Neviere; Fanny Cohen; Céline Gasnier; Afane Brahimi; François Lecoquierre; Jean-Christophe Thery; Isabelle Tennevet; Elodie Lacaze; Pascaline Berthet; Thierry Frebourg
Journal:  Fam Cancer       Date:  2018-07       Impact factor: 2.375

Review 2.  Familial/inherited cancer syndrome: a focus on the highly consanguineous Arab population.

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Journal:  NPJ Genom Med       Date:  2020-02-03       Impact factor: 8.617

Review 3.  Psychological aspects, risk and protective factors related to BRCA genetic testing: a review of the literature.

Authors:  Lucia Lombardi; Sonia M Bramanti; Alessandra Babore; Liborio Stuppia; Carmen Trumello; Ivana Antonucci; Alessandra Cavallo
Journal:  Support Care Cancer       Date:  2019-06-15       Impact factor: 3.603

4.  Psychiatric symptoms in a Spanish sample with hereditary cancer risk.

Authors:  Gema Costa-Requena; Mercedes Garcia-Garijo; Paula Richart-Aznar; Ángel Segura-Huerta
Journal:  J Community Genet       Date:  2022-02-08

5.  Perceptions of risk and reward in BRCA1 and BRCA2 mutation carriers choosing salpingectomy for ovarian cancer prevention.

Authors:  Talayeh S Ghezelayagh; Lauren E Stewart; Barbara M Norquist; Deborah J Bowen; Vivian Yu; Kathy J Agnew; Kathryn P Pennington; Elizabeth M Swisher
Journal:  Fam Cancer       Date:  2020-02-24       Impact factor: 2.375

6.  How does genetic testing influence anxiety, depression, and quality of life? A hereditary breast and ovarian cancer syndrome suspects trial.

Authors:  Francisca Fernanda Barbosa Oliveira; Paulo Goberlânio de Barros Silva; Rosane Oliveira de Sant'Ana; Clarissa Gondim Picanço de Albuquerque; Maria Júlia Barbosa Bezerra; Deysi Viviana Tenazoa Wong; Flávio da Silveira Bitencourt; Isabelle Joyce de Lima Silva-Fernandes; Marcos Venicio Alves Lima
Journal:  Support Care Cancer       Date:  2020-11-05       Impact factor: 3.603

Review 7.  Hereditary Gastric and Breast Cancer Syndromes Related to CDH1 Germline Mutation: A Multidisciplinary Clinical Review.

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Journal:  Cancers (Basel)       Date:  2020-06-17       Impact factor: 6.639

8.  Expectations and psychological issues before genetic counseling: analysis of distress determinant factors.

Authors:  Zelmira Ballatore; Raffaella Bracci; Elena Maccaroni; Lucia Svarca; Francesca Bianchi; Laura Belvederesi; Cristiana Bruciati; Silvia Pagliaretta; Alberto Murrone; Federica Bini; Mirco Pistelli; Giulia Ricci; Rossana Berardi
Journal:  Hered Cancer Clin Pract       Date:  2020-04-29       Impact factor: 2.857

Review 9.  Familial/inherited cancer syndrome: a focus on the highly consanguineous Arab population.

Authors:  Fawz S AlHarthi; Alya Qari; Alaa Edress; Malak Abedalthagafi
Journal:  NPJ Genom Med       Date:  2020-02-03       Impact factor: 8.617

10.  The use of heuristics in genetic testing decision-making: A qualitative interview study.

Authors:  Bettina Maria Zimmermann; David Martin Shaw; Bernice Elger; Insa Koné
Journal:  PLoS One       Date:  2021-11-30       Impact factor: 3.240

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