Literature DB >> 28281540

T(ell)TALE signs of aging.

Reshma Taneja1, Brian K Kennedy1,2,3.   

Abstract

Transcriptional activator-like effectors (TALEs) have emerged as powerful tools for genome editing. A recent study published by Cell Research reports that fusion of thioredoxin to TALEs unlocks their full potential in live-cell imaging to accurately analyze genome instability, telomere attrition and epigenetic alterations that are hallmarks of aging.

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Year:  2017        PMID： 28281540      PMCID： PMC5385616          DOI： 10.1038/cr.2017.33

Source DB:  PubMed          Journal:  Cell Res        ISSN： 1001-0602            Impact factor:   25.617


  11 in total

Review 1.  Higher-order genome organization in human disease.

Authors:  Tom Misteli
Journal:  Cold Spring Harb Perspect Biol       Date:  2010-06-30       Impact factor: 10.005

2.  Visualization of repetitive DNA sequences in human chromosomes with transcription activator-like effectors.

Authors:  Hanhui Ma; Pablo Reyes-Gutierrez; Thoru Pederson
Journal:  Proc Natl Acad Sci U S A       Date:  2013-12-09       Impact factor: 11.205

3.  Live visualization of chromatin dynamics with fluorescent TALEs.

Authors:  Yusuke Miyanari; Céline Ziegler-Birling; Maria-Elena Torres-Padilla
Journal:  Nat Struct Mol Biol       Date:  2013-10-06       Impact factor: 15.369

4.  A simple cipher governs DNA recognition by TAL effectors.

Authors:  Matthew J Moscou; Adam J Bogdanove
Journal:  Science       Date:  2009-12-11       Impact factor: 47.728

5.  Breaking the code of DNA binding specificity of TAL-type III effectors.

Authors:  Jens Boch; Heidi Scholze; Sebastian Schornack; Angelika Landgraf; Simone Hahn; Sabine Kay; Thomas Lahaye; Anja Nickstadt; Ulla Bonas
Journal:  Science       Date:  2009-12-11       Impact factor: 47.728

Review 6.  Thioredoxins and glutaredoxins as facilitators of protein folding.

Authors:  Carsten Berndt; Christopher Horst Lillig; Arne Holmgren
Journal:  Biochim Biophys Acta       Date:  2008-02-19

Review 7.  Imaging Specific Genomic DNA in Living Cells.

Authors:  Baohui Chen; Juan Guan; Bo Huang
Journal:  Annu Rev Biophys       Date:  2016-04-27       Impact factor: 12.981

Review 8.  Ribosomal DNA and cellular senescence: new evidence supporting the connection between rDNA and aging.

Authors:  Austen R D Ganley; Takehiko Kobayashi
Journal:  FEMS Yeast Res       Date:  2014-01-21       Impact factor: 2.796

9.  In vivo localization of DNA sequences and visualization of large-scale chromatin organization using lac operator/repressor recognition.

Authors:  C C Robinett; A Straight; G Li; C Willhelm; G Sudlow; A Murray; A S Belmont
Journal:  J Cell Biol       Date:  1996-12       Impact factor: 10.539

10.  Visualization of aging-associated chromatin alterations with an engineered TALE system.

Authors:  Ruotong Ren; Liping Deng; Yanhong Xue; Keiichiro Suzuki; Weiqi Zhang; Yang Yu; Jun Wu; Liang Sun; Xiaojun Gong; Huiqin Luan; Fan Yang; Zhenyu Ju; Xiaoqing Ren; Si Wang; Hong Tang; Lingling Geng; Weizhou Zhang; Jian Li; Jie Qiao; Tao Xu; Jing Qu; Guang-Hui Liu
Journal:  Cell Res       Date:  2017-01-31       Impact factor: 25.617
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