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Literature DB >> 28276706

Future strategies for the discovery of therapeutic aptamers.

Sorah Yoon¹, John J Rossi^1,2.

Abstract

Entities: Chemical Disease Gene Mutation Species

Keywords: Future strategies; chemical modification; mutant antigens; precision medicine; theranostic aptamers

Mesh：

Substances：
Aptamers, Nucleotide

Year: 2017 PMID： 28276706 PMCID： PMC5654629 DOI： 10.1080/17460441.2017.1290077

Source DB: PubMed Journal: Expert Opin Drug Discov ISSN： 1746-0441 Impact factor: 6.098

× No keyword cloud information.

22 in total

1. Biological activity of bevacizumab, a humanized anti-VEGF antibody in vitro.

Authors: Yaning Wang; David Fei; Martin Vanderlaan; An Song
Journal: Angiogenesis Date: 2005-05-09 Impact factor: 9.596

Review 2. Aptamers as targeted therapeutics: current potential and challenges.

Authors: Jiehua Zhou; John Rossi
Journal: Nat Rev Drug Discov Date: 2016-11-03 Impact factor: 84.694

3. An aptamer-antibody complex (oligobody) as a novel delivery platform for targeted cancer therapies.

Authors: Kyun Heo; Sung-Won Min; Ho Jin Sung; Han Gyul Kim; Hyun Jung Kim; Yun Hee Kim; Beom Kyu Choi; Sewoon Han; Seok Chung; Eun Sook Lee; Junho Chung; In-Hoo Kim
Journal: J Control Release Date: 2016-03-05 Impact factor: 9.776

4. Identification of TIM3 2'-fluoro oligonucleotide aptamer by HT-SELEX for cancer immunotherapy.

Authors: Sandra Hervas-Stubbs; Mario M Soldevilla; Helena Villanueva; Uxua Mancheño; Maurizio Bendandi; Fernando Pastor
Journal: Oncotarget Date: 2016-01-26

5. Pre-existing anti-polyethylene glycol antibody linked to first-exposure allergic reactions to pegnivacogin, a PEGylated RNA aptamer.

Authors: Nancy J Ganson; Thomas J Povsic; Bruce A Sullenger; John H Alexander; Steven L Zelenkofske; Jeffrey M Sailstad; Christopher P Rusconi; Michael S Hershfield
Journal: J Allergy Clin Immunol Date: 2015-12-11 Impact factor: 10.793

6. Linear relationship between deformability and thermal stability of 2'-O-modified RNA hetero duplexes.

Authors: Yoshiaki Masaki; Ryuta Miyasaka; Akihiro Ohkubo; Kohji Seio; Mitsuo Sekine
Journal: J Phys Chem B Date: 2010-02-25 Impact factor: 2.991

7. PASylation: a biological alternative to PEGylation for extending the plasma half-life of pharmaceutically active proteins.

Authors: Martin Schlapschy; Uli Binder; Claudia Börger; Ina Theobald; Klaus Wachinger; Sigrid Kisling; Dirk Haller; Arne Skerra
Journal: Protein Eng Des Sel Date: 2013-06-10 Impact factor: 1.650

8. Evolution of thermophilic DNA polymerases for the recognition and amplification of C2'-modified DNA.

Authors: Tingjian Chen; Narupat Hongdilokkul; Zhixia Liu; Ramkrishna Adhikary; Shujian S Tsuen; Floyd E Romesberg
Journal: Nat Chem Date: 2016-04-18 Impact factor: 24.427

9. Chemically Modified Interleukin-6 Aptamer Inhibits Development of Collagen-Induced Arthritis in Cynomolgus Monkeys.

Authors: Masao Hirota; Ikuo Murakami; Yuichi Ishikawa; Tomoki Suzuki; Shun-ichiro Sumida; Shigeru Ibaragi; Hayato Kasai; Naoto Horai; Daniel W Drolet; Shashi Gupta; Nebojsa Janjic; Daniel J Schneider
Journal: Nucleic Acid Ther Date: 2015-11-18 Impact factor: 5.486

10. Targeting the PD-1/PD-L1 Immune Evasion Axis With DNA Aptamers as a Novel Therapeutic Strategy for the Treatment of Disseminated Cancers.

Authors: Aaron Prodeus; Aws Abdul-Wahid; Nicholas W Fischer; Eric H-B Huang; Marzena Cydzik; Jean Gariépy
Journal: Mol Ther Nucleic Acids Date: 2015-04-28 Impact factor: 10.183

4 in total