Literature DB >> 2826401

Drug-induced relaxation of supercoiled plasmid DNA in Bacillus subtilis and induction of the SOS response.

M S Osburne1, S M Zavodny, G A Peterson.   

Abstract

Whereas treatment with many different drugs led to induction of the SOS response in Bacillus subtilis, only inhibitors of DNA gyrase subunit B and, unexpectedly, polyether antibiotics (membrane ionophores) led to relaxation of supercoiled plasmid DNA. However, treatment with DNA gyrase subunit B inhibitors but not with polyethers led to SOS induction. Thus, the presence of underwound supercoiled DNA was not sufficient to induce the SOS response. Possible mechanisms by which polyethers induce relaxation of supercoiled DNA in vivo are discussed.

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Year:  1988        PMID： 2826401      PMCID： PMC210663          DOI： 10.1128/jb.170.1.442-445.1988

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  26 in total

1.  Superhelical Escherichia coli DNA: relaxation by coumermycin.

Authors:  K Drlica; M Snyder
Journal:  J Mol Biol       Date:  1978-04-05       Impact factor: 5.469

2.  Initiation of DNA replication in Bacillus subtilis. IV. The effect of an intercalating dye, ethidium bromide.

Authors:  H Yoshikawa; N Ogasawara; M Seiki
Journal:  Mol Gen Genet       Date:  1980

3.  Initiation of DNA replication in Bacillus subtilis. V. Role of DNA gyrase and superhelical structure in initiation.

Authors:  N Ogasawara; M Seiki; H Yoshikawa
Journal:  Mol Gen Genet       Date:  1981

4.  Plasmid copy number control: isolation and characterization of high-copy-number mutants of plasmid pE194.

Authors:  B Weisblum; M Y Graham; T Gryczan; D Dubnau
Journal:  J Bacteriol       Date:  1979-01       Impact factor: 3.490

5.  Curing effect of clorobiocin on Escherichia coli plasmids.

Authors:  K Cejka; I Holubová; J Hubácek
Journal:  Mol Gen Genet       Date:  1982

6.  Bacillus subtilis DNA gyrase: purification of subunits and reconstitution of supercoiling activity.

Authors:  E Orr; W L Staudenbauer
Journal:  J Bacteriol       Date:  1982-07       Impact factor: 3.490

7.  Bacillus subtilis deoxyribonucleic acid gyrase.

Authors:  A Sugino; K F Bott
Journal:  J Bacteriol       Date:  1980-03       Impact factor: 3.490

8.  Molecular cloning of genetically active fragments of Bacillus DNA in Bacillus subtilis and properties of the vector plasmid pUB110.

Authors:  K M Keggins; P S Lovett; E J Duvall
Journal:  Proc Natl Acad Sci U S A       Date:  1978-03       Impact factor: 11.205

9.  Curing of Escherichia coli K12 plasmids by coumermycin.

Authors:  O N Danilevskaya; A I Gragerov
Journal:  Mol Gen Genet       Date:  1980-04

10.  DNA-membrane association is necessary for initiation of chromosomal and plasmid replication in Bacillus subtilis.

Authors:  S Winston; N Sueoka
Journal:  Proc Natl Acad Sci U S A       Date:  1980-05       Impact factor: 11.205
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  8 in total

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Journal:  Nucleic Acids Res       Date:  2004-07-01       Impact factor: 16.971

5.  Isolation and characterization of Bacillus subtilis genes involved in siderophore biosynthesis: relationship between B. subtilis sfpo and Escherichia coli entD genes.

Authors:  T H Grossman; M Tuckman; S Ellestad; M S Osburne
Journal:  J Bacteriol       Date:  1993-10       Impact factor: 3.490

6.  PprA Protein Is Involved in Chromosome Segregation via Its Physical and Functional Interaction with DNA Gyrase in Irradiated Deinococcus radiodurans Bacteria.

Authors:  Alice Devigne; Philippe Guérin; Johnny Lisboa; Sophie Quevillon-Cheruel; Jean Armengaud; Suzanne Sommer; Claire Bouthier de la Tour; Pascale Servant
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7.  Comparative Molecular docking analysis of DNA Gyrase subunit A in Pseudomonas aeruginosaPAO1.

Authors:  Aman Gupta; Vanashika Sharma; Ashish Kumar Tewari; Vipul Surenderkumar; Gulshan Wadhwa; Ashwani Mathur; Sanjeev Kumar Sharma; Chakresh Kumar Jain
Journal:  Bioinformation       Date:  2013-02-06

8.  Targeting Bacterial Gyrase with Cystobactamid, Fluoroquinolone, and Aminocoumarin Antibiotics Induces Distinct Molecular Signatures in Pseudomonas aeruginosa.

Authors:  Raimo Franke; Heike Overwin; Susanne Häussler; Mark Brönstrup
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  8 in total

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