Literature DB >> 2825132

Unusual features of CpG-rich (HTF) islands in the human alpha globin complex: association with non-functional pseudogenes and presence within the 3' portion of the zeta gene.

N Fischel-Ghodsian1, R D Nicholls, D R Higgs.   

Abstract

We have characterised a cluster of CpG rich (HTF) islands in the alpha-globin complex and report here two unusual features: The human embryonic zeta 2-globin gene is associated with an HTF island within its 3' portion rather than at the 5' end. Furthermore at least two non-functional pseudogenes within the cluster (psi zeta 1 and psi alpha 2) are associated with CpG rich islands.

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Year:  1987        PMID： 2825132      PMCID： PMC306463          DOI： 10.1093/nar/15.22.9215

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  24 in total

1.  A fraction of the mouse genome that is derived from islands of nonmethylated, CpG-rich DNA.

Authors:  A Bird; M Taggart; M Frommer; O J Miller; D Macleod
Journal:  Cell       Date:  1985-01       Impact factor: 41.582

2.  Identification of DNA sequences required for transcription of the human alpha 1-globin gene in a new SV40 host-vector system.

Authors:  P Mellon; V Parker; Y Gluzman; T Maniatis
Journal:  Cell       Date:  1981-12       Impact factor: 41.582

3.  The structure of the human zeta-globin gene and a closely linked, nearly identical pseudogene.

Authors:  N J Proudfoot; A Gil; T Maniatis
Journal:  Cell       Date:  1982-12       Impact factor: 41.582

4.  "A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity". Addendum.

Authors:  A P Feinberg; B Vogelstein
Journal:  Anal Biochem       Date:  1984-02       Impact factor: 3.365

5.  Long range genome structure around the human alpha-globin complex analysed by PFGE.

Authors:  N Fischel-Ghodsian; R D Nicholls; D R Higgs
Journal:  Nucleic Acids Res       Date:  1987-08-11       Impact factor: 16.971

6.  The mosaic genome of warm-blooded vertebrates.

Authors:  G Bernardi; B Olofsson; J Filipski; M Zerial; J Salinas; G Cuny; M Meunier-Rotival; F Rodier
Journal:  Science       Date:  1985-05-24       Impact factor: 47.728

7.  The chromosomal arrangement of human alpha-like globin genes: sequence homology and alpha-globin gene deletions.

Authors:  J Lauer; C K Shen; T Maniatis
Journal:  Cell       Date:  1980-05       Impact factor: 41.582

8.  Differences in human alpha- and beta-globin gene expression in mouse erythroleukemia cells: the role of intragenic sequences.

Authors:  P Charnay; R Treisman; P Mellon; M Chao; R Axel; T Maniatis
Journal:  Cell       Date:  1984-08       Impact factor: 41.582

9.  Specific methylation pattern at the 3' end of the human housekeeping gene for glucose 6-phosphate dehydrogenase.

Authors:  D Toniolo; M D'Urso; G Martini; M Persico; V Tufano; G Battistuzzi; L Luzzatto
Journal:  EMBO J       Date:  1984-09       Impact factor: 11.598

10.  Cloned human teratoma cells differentiate into neuron-like cells and other cell types in retinoic acid.

Authors:  S Thompson; P L Stern; M Webb; F S Walsh; W Engstrom; E P Evans; W K Shi; B Hopkins; C F Graham
Journal:  J Cell Sci       Date:  1984-12       Impact factor: 5.285
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  16 in total

1.  Molecular analysis of human chromosome 16 cosmid clones containing NotI sites.

Authors:  T Lerner; G Wright; B Leverone; W Dackowski; D Shook; M A Anderson; K Klinger; D Callen; G Landes
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

2.  The mouse surfeit locus contains a cluster of six genes associated with four CpG-rich islands in 32 kilobases of genomic DNA.

Authors:  C Huxley; M Fried
Journal:  Mol Cell Biol       Date:  1990-02       Impact factor: 4.272

3.  CACCC and GATA-1 sequences make the constitutively expressed alpha-globin gene erythroid-responsive in mouse erythroleukemia cells.

Authors:  S Ren; J Li; G F Atweh
Journal:  Nucleic Acids Res       Date:  1996-01-15       Impact factor: 16.971

4.  CpG islands from the alpha-globin gene cluster increase gene expression in an integration-dependent manner.

Authors:  B M Shewchuk; R C Hardison
Journal:  Mol Cell Biol       Date:  1997-10       Impact factor: 4.272

5.  Transcriptional promiscuity of the human alpha-globin gene.

Authors:  E Whitelaw; P Hogben; O Hanscombe; N J Proudfoot
Journal:  Mol Cell Biol       Date:  1989-01       Impact factor: 4.272

6.  A new hypervariable marker for the human alpha-globin gene cluster.

Authors:  A P Jarman; D R Higgs
Journal:  Am J Hum Genet       Date:  1988-09       Impact factor: 11.025

Review 7.  The pseudoautosomal regions of the human sex chromosomes.

Authors:  G A Rappold
Journal:  Hum Genet       Date:  1993-10       Impact factor: 4.132

8.  Nuclear protein-binding sites in a transcriptional control region of the rabbit alpha-globin gene.

Authors:  S E Yost; B Shewchuk; R Hardison
Journal:  Mol Cell Biol       Date:  1993-09       Impact factor: 4.272

9.  The first validated criteria for effective screening and a new simplified method for α-globin gene sequencing for diagnosis of uncommon α-globin mutations.

Authors:  Noppacharn Uaprasert; Rung Settapiboon; Supaporn Amornsiriwat; Pranee Sutcharitchan; Ponlapat Rojnuckarin
Journal:  Int J Hematol       Date:  2017-02-06       Impact factor: 2.490

10.  Gene structure, DNA methylation, and imprinted expression of the human SNRPN gene.

Authors:  C C Glenn; S Saitoh; M T Jong; M M Filbrandt; U Surti; D J Driscoll; R D Nicholls
Journal:  Am J Hum Genet       Date:  1996-02       Impact factor: 11.025
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