Literature DB >> 28151810

Are geographic differences in transplantation inherently wrong?

Keren Ladin1, Douglas W Hanto.   

Abstract

PURPOSE OF REVIEW: Geographic variation in liver transplantation has been the subject of extensive scrutiny, reflecting concerns that location is unfairly determinative for people needing organ transplantation. Drawing upon a number of established ethical approaches, we examine whether geographic differences in access to livers are inherently unethical. RECENT
FINDINGS: We posit that the ethical imperative for redistribution largely hinges upon the belief that access to organs systematically disadvantages certain identifiable groups of patients over others. Yet, our data suggest that regions likely to be net-contributors may suffer from less access to transplantation and other health services, fewer social protections and greater burden of liver disease. Drawing upon a number of ethical approaches, including strict egalitarianism, utilitarianism, Maximin, Reciprocity, Sen's Impartial Spectator and a health equity framework, we demonstrate that the current proposal has significant weaknesses, and may not achieve its goals of improving equity and efficiency.
SUMMARY: Formulating effective policies and programs to ameliorate health inequalities requires an understanding of the interrelated causes of mortality disparities and specific interventions to mitigate these causes. Although our analysis does not indicate how ethically distribute livers, but it suggests that this be done with consideration for population-based health measures.

Entities:  

Mesh:

Year:  2017        PMID: 28151810      PMCID: PMC5772983          DOI: 10.1097/MOT.0000000000000400

Source DB:  PubMed          Journal:  Curr Opin Organ Transplant        ISSN: 1087-2418            Impact factor:   2.640


  12 in total

1.  Organ Procurement Organization Liver Acquisition Costs Could More Than Double With Proposed Redistricts.

Authors:  D F Kappel; W C Chapman; S Conrad; A Reed; R Linderer; S Dunn; P Niles; M F Levy; T Cawiezell
Journal:  Am J Transplant       Date:  2015-06-10       Impact factor: 8.086

2.  Equalizing MELD Scores Over Broad Geographies Is Not the Most Efficacious Way to Allocate a Scarce Resource in a Value-based Environment.

Authors:  Alan Reed; William C Chapman; Stuart Knechtle; Kenneth Chavin; Richard Gilroy; Goran B G Klintmalm
Journal:  Ann Surg       Date:  2015-08       Impact factor: 12.969

3.  Geographic inequities in liver allograft supply and demand: does it affect patient outcomes?

Authors:  Abbas Rana; Bruce Kaplan; Irbaz B Riaz; Marian Porubsky; Shahid Habib; Horacio Rilo; Angelika C Gruessner; Rainer W G Gruessner
Journal:  Transplantation       Date:  2015-03       Impact factor: 4.939

4.  Organ Donation as a Collective Action Problem: Ethical Considerations and Implications for Practice.

Authors:  Keren Ladin
Journal:  AMA J Ethics       Date:  2016-02-01

5.  Potentially Preventable Deaths Among the Five Leading Causes of Death - United States, 2010 and 2014.

Authors:  Macarena C García; Brigham Bastian; Lauren M Rossen; Robert Anderson; Arialdi Miniño; Paula W Yoon; Mark Faul; Greta Massetti; Cheryll C Thomas; Yuling Hong; Michael F Iademarco
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2016-11-18       Impact factor: 17.586

6.  MELD Exceptions and Rates of Waiting List Outcomes.

Authors:  A B Massie; B Caffo; S E Gentry; E C Hall; D A Axelrod; K L Lentine; M A Schnitzler; A Gheorghian; P R Salvalaggio; D L Segev
Journal:  Am J Transplant       Date:  2011-09-15       Impact factor: 8.086

7.  Does Social Capital Explain Community-Level Differences in Organ Donor Designation?

Authors:  Keren Ladin; Rui Wang; Aaron Fleishman; Matthew Boger; James R Rodrigue
Journal:  Milbank Q       Date:  2015-09       Impact factor: 4.911

8.  The impact of proposed changes in liver allocation policy on cold ischemia times and organ transportation costs.

Authors:  D A DuBay; P A MacLennan; R D Reed; M Fouad; M Martin; C B Meeks; G Taylor; M L Kilgore; M Tankersley; S H Gray; J A White; D E Eckhoff; J E Locke
Journal:  Am J Transplant       Date:  2015-02       Impact factor: 8.086

9.  Use of Population-based Data to Demonstrate How Waitlist-based Metrics Overestimate Geographic Disparities in Access to Liver Transplant Care.

Authors:  D S Goldberg; B French; G Sahota; A E Wallace; J D Lewis; S D Halpern
Journal:  Am J Transplant       Date:  2016-05-17       Impact factor: 8.086

10.  The Impact of Redistricting Proposals on Health Care Expenditures for Liver Transplant Candidates and Recipients.

Authors:  S E Gentry; E K H Chow; N Dzebisashvili; M A Schnitzler; K L Lentine; C E Wickliffe; E Shteyn; J Pyke; A Israni; B Kasiske; D L Segev; D A Axelrod
Journal:  Am J Transplant       Date:  2016-01-18       Impact factor: 8.086

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