Literature DB >> 25612501

The impact of proposed changes in liver allocation policy on cold ischemia times and organ transportation costs.

D A DuBay1, P A MacLennan, R D Reed, M Fouad, M Martin, C B Meeks, G Taylor, M L Kilgore, M Tankersley, S H Gray, J A White, D E Eckhoff, J E Locke.   

Abstract

Changes to the liver allocation system have been proposed to decrease regional variation in access to liver transplant. It is unclear what impact these changes will have on cold ischemia times (CITs) and donor transportation costs. Therefore, we performed a retrospective single center study (2008-2012) measuring liver procurement CIT and transportation costs. Four groups were defined: Local-within driving distance (Local-D, n = 262), Local-flight (Local-F, n = 105), Regional-flight <3 h (Regional <3 h, n = 61) and Regional-Flight >3 h (Regional >3 h, n = 53). The median travel distance increased in each group, varying from zero miles (Local-D), 196 miles (Local-F), 384 miles (Regional <3 h), to 1647 miles (Regional >3 h). Increasing travel distances did not significantly increase CIT until the flight time was >3 h. The average CIT ranged from 5.0 to 6.0 h for Local-D, Local-F and Regional <3 h, but increased to 10 h for Regional >3 h (p < 0.0001). Transportation costs increased with greater distance traveled: Local-D $101, Local-F $1993, Regional <3 h $8324 and Regional >3 h $27 810 (p < 0.0001). With proposed redistricting, local financial modeling suggests that the average liver donor procurement transportation variable direct costs will increase from $2415 to $7547/liver donor, an increase of 313%. These findings suggest that further discussion among transplant centers and insurance providers is needed prior to policy implementation. © Copyright 2015 The American Society of Transplantation and the American Society of Transplant Surgeons.

Entities:  

Keywords:  Clinical research/practice; liver transplantation/hepatology; organ allocation; organ procurement and allocation; organ procurement organization

Mesh:

Year:  2015        PMID: 25612501      PMCID: PMC4429785          DOI: 10.1111/ajt.12981

Source DB:  PubMed          Journal:  Am J Transplant        ISSN: 1600-6135            Impact factor:   8.086


  5 in total

1.  The riskiest job in medicine: transplant surgeons and organ procurement travel.

Authors:  M J Englesbe; R M Merion
Journal:  Am J Transplant       Date:  2009-08-06       Impact factor: 8.086

2.  Resource utilization associated with procurement of transplantable organs from donors that do not meet OPTN eligible death criteria.

Authors:  Derek A DuBay; David T Redden; Mary K Bryant; David P Dorn; Mona N Fouad; Stephen H Gray; Jared A White; Jayme E Locke; Christopher B Meeks; Garry C Taylor; Meredith L Kilgore; Devin E Eckhoff
Journal:  Transplantation       Date:  2014-05-27       Impact factor: 4.939

3.  Addressing geographic disparities in liver transplantation through redistricting.

Authors:  S E Gentry; A B Massie; S W Cheek; K L Lentine; E H Chow; C E Wickliffe; N Dzebashvili; P R Salvalaggio; M A Schnitzler; D A Axelrod; D L Segev
Journal:  Am J Transplant       Date:  2013-07-09       Impact factor: 8.086

4.  Characteristics associated with liver graft failure: the concept of a donor risk index.

Authors:  S Feng; N P Goodrich; J L Bragg-Gresham; D M Dykstra; J D Punch; M A DebRoy; S M Greenstein; R M Merion
Journal:  Am J Transplant       Date:  2006-04       Impact factor: 8.086

5.  The economic impact of the utilization of liver allografts with high donor risk index.

Authors:  D A Axelrod; M Schnitzler; P R Salvalaggio; J Swindle; M M Abecassis
Journal:  Am J Transplant       Date:  2007-04       Impact factor: 8.086

  5 in total
  7 in total

Review 1.  Are geographic differences in transplantation inherently wrong?

Authors:  Keren Ladin; Douglas W Hanto
Journal:  Curr Opin Organ Transplant       Date:  2017-04       Impact factor: 2.640

2.  An Initial Investigation of Unmanned Aircraft Systems (UAS) and Real-Time Organ Status Measurement for Transporting Human Organs.

Authors:  Joseph R Scalea; Stephen Restaino; Matthew Scassero; Gil Blankenship; Stephen T Bartlett; Norman Wereley
Journal:  IEEE J Transl Eng Health Med       Date:  2018-11-06       Impact factor: 3.316

3.  Association of the Liver Acuity Circle Allocation Policy With Timing of Donor Procurements in the US.

Authors:  Ramya Radhakrishnan; Darius E Chyou; David Seth Goldberg
Journal:  JAMA Surg       Date:  2022-07-01       Impact factor: 16.681

4.  Waitlist Outcomes of Liver Transplant Candidates Who Were Reprioritized Under Share 35.

Authors:  E K H Chow; A B Massie; X Luo; C E Wickliffe; S E Gentry; A M Cameron; D L Segev
Journal:  Am J Transplant       Date:  2016-08-24       Impact factor: 8.086

5.  Fair is fair: We must re-allocate livers for transplant.

Authors:  Brendan Parent; Arthur L Caplan
Journal:  BMC Med Ethics       Date:  2017-04-05       Impact factor: 2.652

Review 6.  Mesenchymal Stromal Cells, a New Player in Reducing Complications From Liver Transplantation?

Authors:  Andrew Owen; Philip N Newsome
Journal:  Front Immunol       Date:  2020-06-19       Impact factor: 7.561

7.  Dynamic impact of liver allocation policy change on donor utilization.

Authors:  Ethan Chan; April J Logan; Jeffrey M Sneddon; Navdeep Singh; Guy N Brock; William K Washburn; Austin D Schenk
Journal:  Am J Transplant       Date:  2022-03-09       Impact factor: 9.369

  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.