Literature DB >> 28146264

TPMT and NUDT15 genes are both related to mercaptopurine intolerance in acute lymphoblastic leukaemia patients from Uruguay.

Ana M Soler1, Natalia Olano2, Yessika Méndez2, Ana Lopes2, Anaulina Silveira2, Agustin Dabezies2, Luis Castillo2, Julio A da Luz1.   

Abstract

Entities:  

Keywords:  zzm321990zzm321990TPMTzzm321990zzm321990; zzm321990NUDT15zzm321990; 6-Mercaptopurine; Paediatric Acute Lymphoblastic Leukaemia; Pharmacogenetic

Mesh：

Substances：

Year:  2017        PMID： 28146264     DOI： 10.1111/bjh.14532

Source DB:  PubMed          Journal:  Br J Haematol        ISSN： 0007-1048            Impact factor:   6.998


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  9 in total

Review 1.  [Significance of NUDT15 gene in individualized treatment with 6-mercaptopurine in children with acute lymphoblastic leukemia].

Authors:  Jing He; Ling Liu
Journal:  Zhongguo Dang Dai Er Ke Za Zhi       Date:  2019-01

2.  Diplotype analysis of NUDT15 variants and 6-mercaptopurine sensitivity in pediatric lymphoid neoplasms.

Authors:  Shinichi Tsujimoto; Tomoo Osumi; Meri Uchiyama; Ryota Shirai; Takaya Moriyama; Rina Nishii; Yuji Yamada; Ko Kudo; Masahiro Sekiguchi; Yuki Arakawa; Masanori Yoshida; Toru Uchiyama; Kiminori Terui; Shuichi Ito; Katsuyoshi Koh; Junko Takita; Etsuro Ito; Daisuke Tomizawa; Atsushi Manabe; Nobutaka Kiyokawa; Jun J Yang; Motohiro Kato
Journal:  Leukemia       Date:  2018-07-02       Impact factor: 11.528

3.  Impact of NUDT15 genetics on severe thiopurine-related hematotoxicity in patients with European ancestry.

Authors:  Elke Schaeffeler; Simon U Jaeger; Verena Klumpp; Jun J Yang; Svitlana Igel; Laura Hinze; Martin Stanulla; Matthias Schwab
Journal:  Genet Med       Date:  2019-02-07       Impact factor: 8.822

Review 4.  Thiopurines: Recent Topics and Their Role in the Treatment of Inflammatory Bowel Diseases.

Authors:  Keiichi Tominaga; Takeshi Sugaya; Takanao Tanaka; Mimari Kanazawa; Makoto Iijima; Atsushi Irisawa
Journal:  Front Pharmacol       Date:  2021-01-29       Impact factor: 5.810

5.  Susceptibility to thiopurine toxicity by TPMT and NUDT15 variants in Colombian children with acute lymphoblastic leukemia.

Authors:  Oscar Correa-Jimenez; Juan José Yunis; Adriana Linares-Ballesteros; Isabel Sarmiento-Urbina
Journal:  Colomb Med (Cali)       Date:  2021-09-30

6.  Association of Genetic Variants in NUDT15 With Thiopurine-Induced Myelosuppression in Patients With Inflammatory Bowel Disease.

Authors:  Gareth J Walker; James W Harrison; Graham A Heap; Michiel D Voskuil; Vibeke Andersen; Carl A Anderson; Ashwin N Ananthakrishnan; Jeffrey C Barrett; Laurent Beaugerie; Claire M Bewshea; Andy T Cole; Fraser R Cummings; Mark J Daly; Pierre Ellul; Richard N Fedorak; Eleonora A M Festen; Timothy H Florin; Daniel R Gaya; Jonas Halfvarson; Ailsa L Hart; Neel M Heerasing; Peter Hendy; Peter M Irving; Samuel E Jones; Jukka Koskela; James O Lindsay; John C Mansfield; Dermot McGovern; Miles Parkes; Richard C G Pollok; Subramaniam Ramakrishnan; David S Rampton; Manuel A Rivas; Richard K Russell; Michael Schultz; Shaji Sebastian; Philippe Seksik; Abhey Singh; Kenji So; Harry Sokol; Kavitha Subramaniam; Anthony Todd; Vito Annese; Rinse K Weersma; Ramnik Xavier; Rebecca Ward; Michael N Weedon; James R Goodhand; Nicholas A Kennedy; Tariq Ahmad
Journal:  JAMA       Date:  2019-02-26       Impact factor: 56.272

Review 7.  Pharmacogenetics of thiopurines for inflammatory bowel disease in East Asia: prospects for clinical application of NUDT15 genotyping.

Authors:  Yoichi Kakuta; Yoshitaka Kinouchi; Tooru Shimosegawa
Journal:  J Gastroenterol       Date:  2017-11-30       Impact factor: 7.527

8.  Optimal predictor for 6-mercaptopurine intolerance in Chinese children with acute lymphoblastic leukemia: NUDT15, TPMT, or ITPA genetic variants?

Authors:  Hong Zhou; Lei Li; Peng Yang; Lin Yang; Jin E Zheng; Ying Zhou; Yong Han
Journal:  BMC Cancer       Date:  2018-05-02       Impact factor: 4.430

9.  Determination of NUDT15 variants by targeted sequencing can identify compound heterozygosity in pediatric acute lymphoblastic leukemia patients.

Authors:  Chih-Hsiang Yu; Ya-Hsuan Chang; Der-Shiun Wang; Shiann-Tarng Jou; Chien-Yu Lin; Kai-Hsin Lin; Meng-Yao Lu; Lovely Raghav; Hsiu-Hao Chang; Kang-Hsi Wu; Shu-Wei Chou; Yu-Ling Ni; Dong-Tsamn Lin; Shu-Wha Lin; Hsuan-Yu Chen; Yung-Li Yang
Journal:  Sci Rep       Date:  2020-09-01       Impact factor: 4.379
  9 in total

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