| Literature DB >> 28138923 |
Marleah Dean1, Emily A Rauscher2.
Abstract
Women who test positive for a BRCA genetic mutation are at an increased risk for developing hereditary breast and ovarian cancer and have a 50% chance of passing on their genetic mutation to their children. The purpose of this study was to investigate how women who test positive for a BRCA mutation but have not been diagnosed with cancer make decisions regarding family planning. Analysis of interviews with 20 women revealed they engage in logical and emotional decision-making styles. Although women want to be logical to reduce their hereditary cancer risk, emotions often complicate their decision-making. Women experience fear and worry about a future cancer diagnosis, yet also desire to create a family, particularly having children through natural conception. That is, women negotiate having preventative surgeries in a logical doctor-recommended timeframe but also organize those decisions around emotional desires of motherhood. Overall, this study demonstrates the complex decisions women who test positive for a BRCA mutation must make in regards to genetic testing timing, family planning, and overall quality of life.Entities:
Keywords: BRCA1, BRCA2; Decision-making; Disease risk; Family communication; Genetic risk; Genetic testing; Hereditary breast and ovarian cancer; Qualitative research
Mesh:
Year: 2017 PMID: 28138923 DOI: 10.1007/s10897-017-0069-8
Source DB: PubMed Journal: J Genet Couns ISSN: 1059-7700 Impact factor: 2.537