Literature DB >> 28135238

Chromatin biology: Breaking into the PRC2 cage.

Daniel Holoch1, Raphaël Margueron1.   

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Year:  2017        PMID： 28135238     DOI： 10.1038/nchembio.2313

Source DB:  PubMed          Journal:  Nat Chem Biol        ISSN： 1552-4450            Impact factor:   15.040


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  10 in total

1.  Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas.

Authors:  Christopher J Sneeringer; Margaret Porter Scott; Kevin W Kuntz; Sarah K Knutson; Roy M Pollock; Victoria M Richon; Robert A Copeland
Journal:  Proc Natl Acad Sci U S A       Date:  2010-11-15       Impact factor: 11.205

2.  An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED.

Authors:  Wei Qi; Kehao Zhao; Justin Gu; Ying Huang; Youzhen Wang; Hailong Zhang; Man Zhang; Jeff Zhang; Zhengtian Yu; Ling Li; Lin Teng; Shannon Chuai; Chao Zhang; Mengxi Zhao; HoMan Chan; Zijun Chen; Douglas Fang; Qi Fei; Leying Feng; Lijian Feng; Yuan Gao; Hui Ge; Xinjian Ge; Guobin Li; Andreas Lingel; Ying Lin; Yueqin Liu; Fangjun Luo; Minlong Shi; Long Wang; Zhaofu Wang; Yanyan Yu; Jue Zeng; Chenhui Zeng; Lijun Zhang; Qiong Zhang; Shaolian Zhou; Counde Oyang; Peter Atadja; En Li
Journal:  Nat Chem Biol       Date:  2017-01-30       Impact factor: 15.040

3.  The EED protein-protein interaction inhibitor A-395 inactivates the PRC2 complex.

Authors:  Yupeng He; Sujatha Selvaraju; Michael L Curtin; Clarissa G Jakob; Haizhong Zhu; Kenneth M Comess; Bailin Shaw; Juliana The; Evelyne Lima-Fernandes; Magdalena M Szewczyk; Dong Cheng; Kelly L Klinge; Huan-Qiu Li; Marina Pliushchev; Mikkel A Algire; David Maag; Jun Guo; Justin Dietrich; Sanjay C Panchal; Andrew M Petros; Ramzi F Sweis; Maricel Torrent; Lance J Bigelow; Guillermo Senisterra; Fengling Li; Steven Kennedy; Qin Wu; Donald J Osterling; David J Lindley; Wenqing Gao; Scott Galasinski; Dalia Barsyte-Lovejoy; Masoud Vedadi; Fritz G Buchanan; Cheryl H Arrowsmith; Gary G Chiang; Chaohong Sun; William N Pappano
Journal:  Nat Chem Biol       Date:  2017-01-30       Impact factor: 15.040

Review 4.  Maintaining cell identity: PRC2-mediated regulation of transcription and cancer.

Authors:  Itys Comet; Eva M Riising; Benjamin Leblanc; Kristian Helin
Journal:  Nat Rev Cancer       Date:  2016-09-23       Impact factor: 60.716

Review 5.  The Polycomb complex PRC2 and its mark in life.

Authors:  Raphaël Margueron; Danny Reinberg
Journal:  Nature       Date:  2011-01-20       Impact factor: 49.962

6.  Development of secondary mutations in wild-type and mutant EZH2 alleles cooperates to confer resistance to EZH2 inhibitors.

Authors:  V Gibaja; F Shen; J Harari; J Korn; D Ruddy; V Saenz-Vash; H Zhai; T Rejtar; C G Paris; Z Yu; M Lira; D King; W Qi; N Keen; A Q Hassan; H M Chan
Journal:  Oncogene       Date:  2015-04-20       Impact factor: 9.867

7.  Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin.

Authors:  Ryan D Morin; Nathalie A Johnson; Tesa M Severson; Andrew J Mungall; Jianghong An; Rodrigo Goya; Jessica E Paul; Merrill Boyle; Bruce W Woolcock; Florian Kuchenbauer; Damian Yap; R Keith Humphries; Obi L Griffith; Sohrab Shah; Henry Zhu; Michelle Kimbara; Pavel Shashkin; Jean F Charlot; Marianna Tcherpakov; Richard Corbett; Angela Tam; Richard Varhol; Duane Smailus; Michelle Moksa; Yongjun Zhao; Allen Delaney; Hong Qian; Inanc Birol; Jacqueline Schein; Richard Moore; Robert Holt; Doug E Horsman; Joseph M Connors; Steven Jones; Samuel Aparicio; Martin Hirst; Randy D Gascoyne; Marco A Marra
Journal:  Nat Genet       Date:  2010-01-17       Impact factor: 38.330

8.  Role of the polycomb protein EED in the propagation of repressive histone marks.

Authors:  Raphael Margueron; Neil Justin; Katsuhito Ohno; Miriam L Sharpe; Jinsook Son; William J Drury; Philipp Voigt; Stephen R Martin; William R Taylor; Valeria De Marco; Vincenzo Pirrotta; Danny Reinberg; Steven J Gamblin
Journal:  Nature       Date:  2009-09-20       Impact factor: 49.962

9.  Targeted disruption of the EZH2-EED complex inhibits EZH2-dependent cancer.

Authors:  Woojin Kim; Gregory H Bird; Tobias Neff; Guoji Guo; Marc A Kerenyi; Loren D Walensky; Stuart H Orkin
Journal:  Nat Chem Biol       Date:  2013-08-25       Impact factor: 15.040

10.  Acquisition of a single EZH2 D1 domain mutation confers acquired resistance to EZH2-targeted inhibitors.

Authors:  Theresa Baker; Sujata Nerle; Justin Pritchard; Boyang Zhao; Victor M Rivera; Andrew Garner; Francois Gonzalvez
Journal:  Oncotarget       Date:  2015-10-20
  10 in total
  2 in total

1.  CTCF-mediated chromatin looping in EGR2 regulation and SUZ12 recruitment critical for peripheral myelination and repair.

Authors:  Jincheng Wang; Jiajia Wang; Lijun Yang; Chuntao Zhao; Laiman Natalie Wu; Lingli Xu; Feng Zhang; Qinjie Weng; Michael Wegner; Q Richard Lu
Journal:  Nat Commun       Date:  2020-08-17       Impact factor: 14.919

2.  Chidamide epigenetically represses autophagy and exerts cooperative antimyeloma activity with bortezomib.

Authors:  Li Xu; Juan Feng; Hailong Tang; Ying Dong; Mimi Shu; Xiequn Chen
Journal:  Cell Death Dis       Date:  2020-04-27       Impact factor: 8.469
  2 in total

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