Literature DB >> 2813060

Synthesis of cyclic oligodeoxyribonucleotides via the 'filtration' approach.

M V Rao1, C B Reese.   

Abstract

The synthesis of cyclic di-, tri-, tetra-, penta- and hexa-thymidylic acids (16; n = 2, 3, 4, 5 and 6) and the cyclic hexadeoxyribonucleotide [d(CpCpTpApGpGp)], via the "filtration" approach, is reported. Some of the physical properties of the cyclic oligonucleotides are discussed, and their susceptibility to digestion in the presence of phosphorylytic enzymes has been studied.

Entities:  

Mesh：

Substances：

Year:  1989        PMID： 2813060      PMCID： PMC334960          DOI： 10.1093/nar/17.20.8221

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  4 in total

1.  Rapid synthesis of oligodeoxyribonucleotides. IV. Improved solid phase synthesis of oligodeoxyribonucleotides through phosphotriester intermediates.

Authors:  M J Gait; M Singh; R C Sheppard; M D Edge; A R Greene; G R Heathcliffe; T C Atkinson; C R Newton; A F Markham
Journal:  Nucleic Acids Res       Date:  1980-03-11       Impact factor: 16.971

2.  Prevention of chain cleavage in the chemical synthesis of 2'-silylated oligoribonucleotides.

Authors:  T Wu; K K Ogilvie; R T Pon
Journal:  Nucleic Acids Res       Date:  1989-05-11       Impact factor: 16.971

3.  Some observations relating to the oximate ion promoted unblocking of oligonucleotide aryl esters.

Authors:  C B Reese; L Zard
Journal:  Nucleic Acids Res       Date:  1981-09-25       Impact factor: 16.971

4.  Synthesis of cyclic oligonucleotides by a modified phosphotriester approach.

Authors:  E de Vroom; H J Broxterman; L A Sliedregt; G A van der Marel; J H van Boom
Journal:  Nucleic Acids Res       Date:  1988-05-25       Impact factor: 16.971
  4 in total
  5 in total

1.  Preorganization of DNA: Design Principles for Improving Nucleic Acid Recognition by Synthetic Oligonucleotides.

Authors:  Eric T. Kool
Journal:  Chem Rev       Date:  1997-08-05       Impact factor: 60.622

2.  Design and synthesis of RNA miniduplexes via a synthetic linker approach. 2. Generation of covalently closed, double-stranded cyclic HIV-1 TAR RNA analogs with high Tat-binding affinity.

Authors:  M Y X Ma; K McCallum; S C Climie; R Kuperman; W C Lin; M Sumner-Smith; R W Barnett
Journal:  Nucleic Acids Res       Date:  1993-06-11       Impact factor: 16.971

3.  Circulation of oligonucleotides by disulfide bridge formation.

Authors:  H Gao; M Yang; R Patel; A F Cook
Journal:  Nucleic Acids Res       Date:  1995-06-11       Impact factor: 16.971

4.  One pot solution synthesis of cyclic oligodeoxyribonucleotides.

Authors:  M L Capobianco; A Carcuro; L Tondelli; A Garbesi; G M Bonora
Journal:  Nucleic Acids Res       Date:  1990-05-11       Impact factor: 16.971

5.  Oligonucleotide circularization by template-directed chemical ligation.

Authors:  N G Dolinnaya; M Blumenfeld; I N Merenkova; T S Oretskaya; N F Krynetskaya; M G Ivanovskaya; M Vasseur; Z A Shabarova
Journal:  Nucleic Acids Res       Date:  1993-11-25       Impact factor: 16.971
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.