Literature DB >> 28115353

In Vitro Antifungal Susceptibility Testing of Candida Isolates with the EUCAST Methodology, a New Method for ECOFF Determination.

J Meletiadis1,2, I Curfs-Breuker3, J F Meis3,4, J W Mouton2.   

Abstract

The in vitro susceptibilities of 1,099 molecularly identified clinical Candida isolates against 8 antifungal drugs were determined using the EUCAST microdilution method. A new simple, objective, and mathematically solid method for determining epidemiological cutoff values (ECOFFs) was developed by derivatizing the MIC distribution and determining the derivatized ECOFF (dECOFF) as the highest MIC with the maximum second derivative. The dECOFFs were similar (95% agreement within 1 dilution) to the EUCAST ECOFFs. Overall, low non-wild-type/resistance rates were found. The highest rates were found for azoles with C. parapsilosis (2.7 to 9.8%), C. albicans (7%), and C. glabrata (1.7 to 2.3%) and for echinocandins with C. krusei (3.3%), C. albicans (1%), and C. tropicalis (1.7%).
Copyright © 2017 American Society for Microbiology.

Entities:  

Keywords:  Candida; EUCAST; antifungal susceptibility testing; epidemiological cutoff value

Mesh：

Substances：

Year:  2017        PMID： 28115353      PMCID： PMC5365691          DOI： 10.1128/AAC.02372-16

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  11 in total

1.  Candida species distribution and antifungal susceptibility testing according to European Committee on Antimicrobial Susceptibility Testing and new vs. old Clinical and Laboratory Standards Institute clinical breakpoints: a 6-year prospective candidaemia survey from the fungal infection network of Switzerland.

Authors:  C Orasch; O Marchetti; J Garbino; J Schrenzel; S Zimmerli; K Mühlethaler; G Pfyffer; C Ruef; J Fehr; R Zbinden; T Calandra; J Bille
Journal:  Clin Microbiol Infect       Date:  2013-12-12       Impact factor: 8.067

2.  Susceptibility of Candida species and various moulds to antimycotic drugs: use of epidemiological cutoff values according to EUCAST and CLSI in an 8-year survey.

Authors:  Günter Rambach; Heidemarie Oberhauser; Cornelia Speth; Cornelia Lass-Flörl
Journal:  Med Mycol       Date:  2011-05-30       Impact factor: 4.076

3.  Statistical characterisation of bacterial wild-type MIC value distributions and the determination of epidemiological cut-off values.

Authors:  J Turnidge; G Kahlmeter; G Kronvall
Journal:  Clin Microbiol Infect       Date:  2006-05       Impact factor: 8.067

4.  Intra- and Interlaboratory Agreement in Assessing the In Vitro Activity of Micafungin against Common and Rare Candida Species with the EUCAST, CLSI, and Etest Methods.

Authors:  J Meletiadis; E Geertsen; I Curfs-Breuker; J F Meis; J W Mouton
Journal:  Antimicrob Agents Chemother       Date:  2016-09-23       Impact factor: 5.191

5.  Epidemiological cutoff values for azoles and Aspergillus fumigatus based on a novel mathematical approach incorporating cyp51A sequence analysis.

Authors:  J Meletiadis; E Mavridou; W J G Melchers; J W Mouton; P E Verweij
Journal:  Antimicrob Agents Chemother       Date:  2012-02-13       Impact factor: 5.191

6.  Molecular identification and antifungal susceptibility of yeast isolates causing fungemia collected in a population-based study in Spain in 2010 and 2011.

Authors:  Jesús Guinea; Óscar Zaragoza; Pilar Escribano; Estrella Martín-Mazuelos; Javier Pemán; Ferrán Sánchez-Reus; Manuel Cuenca-Estrella
Journal:  Antimicrob Agents Chemother       Date:  2013-12-23       Impact factor: 5.191

7.  Species distribution and in vitro antifungal susceptibility profiles of yeast isolates from invasive infections during a Portuguese multicenter survey.

Authors:  I Faria-Ramos; J Neves-Maia; E Ricardo; J Santos-Antunes; A T Silva; S Costa-de-Oliveira; E Cantón; A G Rodrigues; C Pina-Vaz
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2014-07-11       Impact factor: 3.267

Review 8.  The role of epidemiological cutoff values (ECVs/ECOFFs) in antifungal susceptibility testing and interpretation for uncommon yeasts and moulds.

Authors:  Ana Espinel-Ingroff; John Turnidge
Journal:  Rev Iberoam Micol       Date:  2016-06-11       Impact factor: 1.044

9.  Evidence of genotypic diversity among Candida auris isolates by multilocus sequence typing, matrix-assisted laser desorption ionization time-of-flight mass spectrometry and amplified fragment length polymorphism.

Authors:  A Prakash; C Sharma; A Singh; P Kumar Singh; A Kumar; F Hagen; N P Govender; A L Colombo; J F Meis; A Chowdhary
Journal:  Clin Microbiol Infect       Date:  2015-11-05       Impact factor: 8.067

10.  Species distribution and susceptibility profile to fluconazole, voriconazole and MXP-4509 of 551 clinical yeast isolates from a Romanian multi-centre study.

Authors:  B Minea; V Nastasa; R F Moraru; A Kolecka; M M Flonta; I Marincu; A Man; F Toma; M Lupse; B Doroftei; N Marangoci; M Pinteala; T Boekhout; M Mares
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2014-09-16       Impact factor: 3.267
View more
  19 in total

1.  Comparison of MIC Test Strip and Sensititre YeastOne with the CLSI and EUCAST Broth Microdilution Reference Methods for In Vitro Antifungal Susceptibility Testing of Cryptococcus neoformans.

Authors:  Fatima Zohra Delma; Abdullah M S Al-Hatmi; Jochem B Buil; Hein van der Lee; Marlou Tehupeiory-Kooreman; G Sybren de Hoog; Joseph Meletiadis; Paul E Verweij
Journal:  Antimicrob Agents Chemother       Date:  2020-03-24       Impact factor: 5.191

2.  Posaconazole MIC Distributions for Aspergillus fumigatus Species Complex by Four Methods: Impact of cyp51A Mutations on Estimation of Epidemiological Cutoff Values.

Authors:  A Espinel-Ingroff; J Turnidge; A Alastruey-Izquierdo; E Dannaoui; G Garcia-Effron; J Guinea; S Kidd; T Pelaez; M Sanguinetti; J Meletiadis; F Botterel; B Bustamante; Y-C Chen; A Chakrabarti; A Chowdhary; E Chryssanthou; S Córdoba; G M Gonzalez; J Guarro; E M Johnson; J V Kus; C Lass-Flörl; M J Linares-Sicilia; E Martín-Mazuelos; C E Negri; M A Pfaller; A M Tortorano
Journal:  Antimicrob Agents Chemother       Date:  2018-03-27       Impact factor: 5.191

Review 3.  Candida parapsilosis: from Genes to the Bedside.

Authors:  Renáta Tóth; Jozef Nosek; Héctor M Mora-Montes; Toni Gabaldon; Joseph M Bliss; Joshua D Nosanchuk; Siobhán A Turner; Geraldine Butler; Csaba Vágvölgyi; Attila Gácser
Journal:  Clin Microbiol Rev       Date:  2019-02-27       Impact factor: 26.132

4.  Method-Dependent Epidemiological Cutoff Values for Detection of Triazole Resistance in Candida and Aspergillus Species for the Sensititre YeastOne Colorimetric Broth and Etest Agar Diffusion Methods.

Authors:  A Espinel-Ingroff; J Turnidge; A Alastruey-Izquierdo; F Botterel; E Canton; C Castro; Y-C Chen; Y Chen; E Chryssanthou; E Dannaoui; G Garcia-Effron; G M Gonzalez; N P Govender; J Guinea; S Kidd; M Lackner; C Lass-Flörl; M J Linares-Sicilia; L López-Soria; R Magobo; T Pelaez; G Quindós; M A Rodriguez-Iglesia; M A Ruiz; F Sánchez-Reus; M Sanguinetti; R Shields; P Szweda; A Tortorano; N L Wengenack; S Bramati; C Cavanna; C DeLuca; M Gelmi; A Grancini; G Lombardi; J Meletiadis; C E Negri; M Passera; J Peman; A Prigitano; E Sala; M Tejada
Journal:  Antimicrob Agents Chemother       Date:  2018-12-21       Impact factor: 5.191

5.  Comparison of EUCAST and CLSI Reference Microdilution MICs of Eight Antifungal Compounds for Candida auris and Associated Tentative Epidemiological Cutoff Values.

Authors:  M C Arendrup; Anupam Prakash; Joseph Meletiadis; Cheshta Sharma; Anuradha Chowdhary
Journal:  Antimicrob Agents Chemother       Date:  2017-05-24       Impact factor: 5.191

6.  Characterization and functional analysis of zinc trafficking in the human fungal pathogen Candida parapsilosis.

Authors:  Tamás Takács; Mihály Tibor Németh; Flóra Bohner; Csaba Vágvölgyi; Ferenc Jankovics; Duncan Wilson; Attila Gácser
Journal:  Open Biol       Date:  2022-07-13       Impact factor: 7.124

7.  Echinocandins Susceptibility Patterns of 2,787 Yeast Isolates: Importance of the Thresholds for the Detection of FKS Mutations.

Authors:  Marie Desnos-Ollivier; Stéphane Bretagne; Olivier Lortholary; Françoise Dromer
Journal:  Antimicrob Agents Chemother       Date:  2022-04-12       Impact factor: 5.938

Review 8.  Drug resistance and tolerance in fungi.

Authors:  Judith Berman; Damian J Krysan
Journal:  Nat Rev Microbiol       Date:  2020-02-11       Impact factor: 60.633

Review 9.  Mechanisms of Candida Resistance to Antimycotics and Promising Ways to Overcome It: The Role of Probiotics.

Authors:  Konstantin A Demin; Aleksandr G Refeld; Anna A Bogdanova; Evgenya V Prazdnova; Igor V Popov; Olga Yu Kutsevalova; Alexey M Ermakov; Anzhelica B Bren; Dmitry V Rudoy; Vladimir A Chistyakov; Richard Weeks; Michael L Chikindas
Journal:  Probiotics Antimicrob Proteins       Date:  2021-03-18       Impact factor: 4.609

10.  Candida parapsilosis endocarditis. Report of cases and review of the literature.

Authors:  Petros Ioannou; Maria Volosyraki; Vasiliki Mavrikaki; Ioanna Papakitsou; Anna Mathioudaki; George Samonis; Diamantis P Kofteridis
Journal:  Germs       Date:  2020-09-01
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.