Literature DB >> 28092334

Is Enhanced Recovery the New Standard of Care in Microsurgical Breast Reconstruction?

Anoushka Afonso1,2, Sabine Oskar1,2, Kay See Tan1,2, Joseph J Disa1,2, Babak J Mehrara1,2, Jihan Ceyhan1,2, Joseph H Dayan1,2.   

Abstract

BACKGROUND: At present, there are limited data available regarding the use and feasibility of enhanced recovery pathways for patients undergoing microsurgical breast reconstruction. The authors sought to assess patient outcomes before and after the introduction of an enhanced recovery pathway that was adopted at a single cancer center.
METHODS: A multidisciplinary enhanced recovery pathway was developed for patients undergoing deep inferior epigastric perforator or free transverse rectus abdominis myocutaneous flap breast reconstruction. Core elements of the enhanced recovery pathway included substituting intravenous patient-controlled analgesia with ketorolac and transversus abdominis plane blocks using liposomal bupivacaine, as well as intraoperative goal-directed fluid management. Patients who underwent surgery between April and August of 2015 using the enhanced recovery pathway were compared with a historical control cohort. The primary endpoints were hospital length of stay and total postoperative opioid consumption.
RESULTS: In total, 91 consecutive patients were analyzed (enhanced recovery pathway, n = 42; pre-enhanced recovery pathway, n = 49). Mean hospital length of stay was significantly shorter in the enhanced recovery pathway group than in the pre-enhanced recovery pathway group (4.0 days versus 5.0 days; p < 0.0001). Total postoperative morphine equivalent consumption was also lower in the enhanced recovery pathway group (46.0 mg versus 70.5 mg; p = 0.003). There was no difference in the incidence of 30-day complications between the groups (p = 0.6).
CONCLUSION: The adoption of an enhanced recovery pathway for deep inferior epigastric perforator and transverse rectus abdominis myocutaneous flap reconstruction by multiple surgeons significantly decreased opioid consumption and reduced length of stay by 1 day. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, III.

Entities:  

Mesh:

Year:  2017        PMID: 28092334      PMCID: PMC5640259          DOI: 10.1097/PRS.0000000000003235

Source DB:  PubMed          Journal:  Plast Reconstr Surg        ISSN: 0032-1052            Impact factor:   4.730


  31 in total

Review 1.  Anaesthesia, surgery, and challenges in postoperative recovery.

Authors:  Henrik Kehlet; Jørgen B Dahl
Journal:  Lancet       Date:  2003-12-06       Impact factor: 79.321

2.  The future of fast-track surgery.

Authors:  H Kehlet; K Slim
Journal:  Br J Surg       Date:  2012-06-14       Impact factor: 6.939

Review 3.  Evidence-based review of enhancing postoperative recovery after breast surgery.

Authors:  R Arsalani-Zadeh; D ElFadl; N Yassin; J MacFie
Journal:  Br J Surg       Date:  2011-02       Impact factor: 6.939

4.  Guidelines for pre- and intra-operative care in gynecologic/oncology surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations--Part I.

Authors:  G Nelson; A D Altman; A Nick; L A Meyer; P T Ramirez; C Achtari; J Antrobus; J Huang; M Scott; L Wijk; N Acheson; O Ljungqvist; S C Dowdy
Journal:  Gynecol Oncol       Date:  2015-11-18       Impact factor: 5.482

Review 5.  Consensus review of optimal perioperative care in colorectal surgery: Enhanced Recovery After Surgery (ERAS) Group recommendations.

Authors:  Kristoffer Lassen; Mattias Soop; Jonas Nygren; P Boris W Cox; Paul O Hendry; Claudia Spies; Maarten F von Meyenfeldt; Kenneth C H Fearon; Arthur Revhaug; Stig Norderval; Olle Ljungqvist; Dileep N Lobo; Cornelis H C Dejong
Journal:  Arch Surg       Date:  2009-10

6.  Enhanced recovery pathways optimize health outcomes and resource utilization: a meta-analysis of randomized controlled trials in colorectal surgery.

Authors:  Michel Adamina; Henrik Kehlet; George A Tomlinson; Anthony J Senagore; Conor P Delaney
Journal:  Surgery       Date:  2011-01-14       Impact factor: 3.982

7.  Incidence of hematoma associated with ketorolac after TRAM flap breast reconstruction.

Authors:  S Sharma; D W Chang; C Koutz; G R Evans; G L Robb; H N Langstein; S S Kroll
Journal:  Plast Reconstr Surg       Date:  2001-02       Impact factor: 4.730

8.  Enhanced recovery after surgery (ERAS) for head and neck oncology patients.

Authors:  M J Coyle; B Main; C Hughes; R Craven; R Alexander; G Porter; S Thomas
Journal:  Clin Otolaryngol       Date:  2016-02-07       Impact factor: 2.597

9.  Ketorolac does not increase perioperative bleeding: a meta-analysis of randomized controlled trials.

Authors:  Ryan M Gobble; Han L T Hoang; Bart Kachniarz; Dennis P Orgill
Journal:  Plast Reconstr Surg       Date:  2014-03       Impact factor: 4.730

10.  Introduction of an enhanced recovery protocol for radical cystectomy.

Authors:  Nimalan Arumainayagam; John McGrath; Kieran P Jefferson; David A Gillatt
Journal:  BJU Int       Date:  2008-01-08       Impact factor: 5.588

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  19 in total

Review 1.  Enhanced Recovery Pathways for Flap-Based Reconstruction: Systematic Review and Meta-Analysis.

Authors:  Yan Yu Tan; Frank Liaw; Robert Warner; Simon Myers; Ali Ghanem
Journal:  Aesthetic Plast Surg       Date:  2021-04-05       Impact factor: 2.326

2.  Gender-affirming Phalloplasty: A Postoperative Protocol for Success.

Authors:  William J Rifkin; David A Daar; Courtney N Cripps; Ginger Mars; Lee C Zhao; Jamie P Levine; Rachel Bluebond-Langner
Journal:  Plast Reconstr Surg Glob Open       Date:  2022-06-20

3.  Organization of Multidisciplinary Cancer Care for the Surgical Patient: Role of Anesthesiologists.

Authors:  Elizabeth F Rieth; Gregory W Fischer; Anoushka M Afonso
Journal:  Curr Anesthesiol Rep       Date:  2018-10-08

4.  Perioperative Inpatient Opioid Consumption Following Autologous Free-Flap Breast Reconstruction Patients: An Examination of Risk and Patient-Reported Outcomes.

Authors:  Jonas A Nelson; Thais O Polanco; Meghana G Shamsunder; Michelle Coriddi; Evan Matros; Madeleine E V Hicks; Joseph J Disa; Babak J Mehrara; Robert J Allen; Joseph H Dayan; Anoushka Afonso
Journal:  Ann Surg Oncol       Date:  2021-05-06       Impact factor: 4.339

5.  Goal-directed fluid therapy in autologous breast reconstruction results in less fluid and more vasopressor administration without outcome compromise.

Authors:  Thais O Polanco; Meghana G Shamsunder; Madeleine E V Hicks; Kenneth P Seier; Kay See Tan; Sabine Oskar; Joseph H Dayan; Joseph J Disa; Babak J Mehrara; Robert J Allen; Jonas A Nelson; Anoushka M Afonso
Journal:  J Plast Reconstr Aesthet Surg       Date:  2021-02-04       Impact factor: 3.022

6.  An Enhanced Recovery after Surgery Pathway for Microvascular Breast Reconstruction Is Safe and Effective.

Authors:  Arezoo Astanehe; Claire Temple-Oberle; Markus Nielsen; William de Haas; Robert Lindsay; Jennifer Matthews; David C McKenzie; Justin Yeung; Christiaan Schrag
Journal:  Plast Reconstr Surg Glob Open       Date:  2018-01-18

Review 7.  Paravertebral blocks and enhanced recovery after surgery protocols in breast reconstructive surgery: patient selection and perspectives.

Authors:  Rajiv P Parikh; Terence M Myckatyn
Journal:  J Pain Res       Date:  2018-08-23       Impact factor: 3.133

8.  Adoption of Enhanced Recovery after Surgery Protocols in Breast Reconstruction in Alberta Is High before a Formal Program Implementation.

Authors:  Jennifer N Redwood; Ashlee E Matkin; Claire F Temple-Oberle
Journal:  Plast Reconstr Surg Glob Open       Date:  2019-05-16

9.  The impact of co-surgeons on complication rates and healthcare cost in patients undergoing microsurgical breast reconstruction: analysis of 8680 patients.

Authors:  Malke Asaad; Ying Xu; Carrie K Chu; Ya-Chen Tina Shih; Alexander F Mericli
Journal:  Breast Cancer Res Treat       Date:  2020-08-16       Impact factor: 4.872

10.  Examining Length of Hospital Stay after Microsurgical Breast Reconstruction: Evaluation in a Case-Control Study.

Authors:  Jordan D Frey; Ara A Salibian; Nolan S Karp; Mihye Choi
Journal:  Plast Reconstr Surg Glob Open       Date:  2017-12-28
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