Literature DB >> 21236454

Enhanced recovery pathways optimize health outcomes and resource utilization: a meta-analysis of randomized controlled trials in colorectal surgery.

Michel Adamina1, Henrik Kehlet, George A Tomlinson, Anthony J Senagore, Conor P Delaney.   

Abstract

BACKGROUND: Health care systems provide care to increasingly complex and elderly patients. Colorectal surgery is a prime example, with high volumes of major procedures, significant morbidity, prolonged hospital stays, and unplanned readmissions. This situation is exacerbated by an exponential rise in costs that threatens the stability of health care systems. Enhanced recovery pathways (ERP) have been proposed as a means to reduce morbidity and improve effectiveness of care. We have reviewed the evidence supporting the implementation of ERP in clinical practice.
METHODS: Medline, Embase, and the Cochrane library were searched for randomized, controlled trials comparing ERP with traditional care in colorectal surgery. Systematic reviews and papers on ERP based on data published in major surgical and anesthesiology journals were critically reviewed by international contributors, experienced in the development and implementation of ERP.
RESULTS: A random-effect Bayesian meta-analysis was performed, including 6 randomized, controlled trials totalizing 452 patients. For patients adhering to ERP, length of stay decreased by 2.5 days (95% credible interval [CrI] -3.92 to -1.11), whereas 30-day morbidity was halved (relative risk, 0.52; 95% CrI, 0.36-0.73) and readmission was not increased (relative risk, 0.59; 95% CrI, 0.14-1.43) when compared with patients undergoing traditional care.
CONCLUSION: Adherence to ERP achieves a reproducible improvement in the quality of care by enabling standardization of health care processes. Thus, while accelerating recovery and safely reducing hospital stay, ERPs optimize utilization of health care resources. ERPs can and should be routinely used in care after colorectal and other major gastrointestinal procedures.
Copyright © 2011 Mosby, Inc. All rights reserved.

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Year:  2011        PMID: 21236454     DOI: 10.1016/j.surg.2010.11.003

Source DB:  PubMed          Journal:  Surgery        ISSN: 0039-6060            Impact factor:   3.982


  141 in total

1.  Enhanced recovery program following colorectal resection in the elderly patient.

Authors:  Nikhil Pawa; Paul L Cathcart; Tan H A Arulampalam; Matthew G Tutton; Roger W Motson
Journal:  World J Surg       Date:  2012-02       Impact factor: 3.352

Review 2.  Adoption of enhanced recovery after surgery (ERAS) strategies for colorectal surgery at academic teaching hospitals and impact on total length of hospital stay.

Authors:  Mary-Anne Aarts; Allan Okrainec; Amy Glicksman; Emily Pearsall; J Charles Victor; Robin S McLeod
Journal:  Surg Endosc       Date:  2011-10-20       Impact factor: 4.584

3.  [Fast-track: evaluation of a new concept].

Authors:  W Schwenk
Journal:  Chirurg       Date:  2012-04       Impact factor: 0.955

4.  Fast-track for the modern colorectal department.

Authors:  Rishabh Sehgal; Arnold Hill; Joseph Deasy; Deborah A McNamara; Ronan A Cahill
Journal:  World J Surg       Date:  2012-10       Impact factor: 3.352

5.  A prospective case-control study of extralevator abdominoperineal excision (ELAPE) of the rectum versus conventional laparoscopic and open abdominoperineal excision: comparative analysis of short-term outcomes and quality of life.

Authors:  P G Vaughan-Shaw; T Cheung; J S Knight; P H Nichols; S A Pilkington; A H Mirnezami
Journal:  Tech Coloproctol       Date:  2012-07-10       Impact factor: 3.781

6.  Laparoscopic Colectomy and the General Surgeon.

Authors:  Jesse Moore; Andrew Pellet; Neil Hyman
Journal:  J Gastrointest Surg       Date:  2015-09-18       Impact factor: 3.452

7.  Identifying causes for high readmission rates after stoma reversal.

Authors:  Deborah S Keller; Zhamak Khorgami; Brian Swendseid; Sadaf Khan; Conor P Delaney
Journal:  Surg Endosc       Date:  2013-11-27       Impact factor: 4.584

8.  Limited preoperative physical capacity continues to be associated with poor postoperative outcomes within a colorectal ERAS programme.

Authors:  E McLennan; R Oliphant; S J Moug
Journal:  Ann R Coll Surg Engl       Date:  2019-01-15       Impact factor: 1.891

9.  Short-term outcomes and benefits of ERAS program in elderly patients undergoing colorectal surgery: a case-matched study compared to conventional care.

Authors:  Patricia Tejedor; Carlos Pastor; Santiago Gonzalez-Ayora; Mario Ortega-Lopez; Hector Guadalajara; Damian Garcia-Olmo
Journal:  Int J Colorectal Dis       Date:  2018-05-03       Impact factor: 2.571

10.  Comprehensive enhanced recovery pathway significantly reduces postoperative length of stay and opioid usage in elective laparoscopic colectomy.

Authors:  Martin P Alvarez; Katherine E Foley; D Mark Zebley; Steven A Fassler
Journal:  Surg Endosc       Date:  2014-12-06       Impact factor: 4.584

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