Julio Acosta-Navarro1, Luiza Antoniazzi2, Adriana Midori Oki3, Maria Carlos Bonfim4, Valeria Hong5, Pedro Acosta-Cardenas6, Celia Strunz7, Eleonora Brunoro8, Marcio Hiroshi Miname9, Wilson Salgado Filho10, Luiz Aparecido Bortolotto11, Raul D Santos12. 1. Lipid Clinic Heart Institute (InCor), University of São Paulo Medical School Hospital, São Paulo, Brazil; Osiris Florindo Coelho Regional Hospital of Ferraz de Vasconcelos, Brazil. Electronic address: jnavarro_2@hotmail.com. 2. Lipid Clinic Heart Institute (InCor), University of São Paulo Medical School Hospital, São Paulo, Brazil; Paulista University (UNIP), Brazil. Electronic address: lgouveia@usp.br. 3. Lipid Clinic Heart Institute (InCor), University of São Paulo Medical School Hospital, São Paulo, Brazil. Electronic address: dri_oki@hotmail.com. 4. Lipid Clinic Heart Institute (InCor), University of São Paulo Medical School Hospital, São Paulo, Brazil. Electronic address: maria.bonfim@hotmail.com. 5. Lipid Clinic Heart Institute (InCor), University of São Paulo Medical School Hospital, São Paulo, Brazil. Electronic address: hong.valeria@gmail.com. 6. Lipid Clinic Heart Institute (InCor), University of São Paulo Medical School Hospital, São Paulo, Brazil. Electronic address: pedrovoltron1@hotmail.com. 7. Lipid Clinic Heart Institute (InCor), University of São Paulo Medical School Hospital, São Paulo, Brazil. Electronic address: labcelia@incor.usp.br. 8. Lipid Clinic Heart Institute (InCor), University of São Paulo Medical School Hospital, São Paulo, Brazil. Electronic address: eleonora.brunoro@incor.usp.br. 9. Lipid Clinic Heart Institute (InCor), University of São Paulo Medical School Hospital, São Paulo, Brazil. Electronic address: marmin@bol.com.br. 10. Lipid Clinic Heart Institute (InCor), University of São Paulo Medical School Hospital, São Paulo, Brazil. Electronic address: wilson.salgado@incor.usp.br. 11. Lipid Clinic Heart Institute (InCor), University of São Paulo Medical School Hospital, São Paulo, Brazil. Electronic address: hipluiz@incor.usp.br. 12. Lipid Clinic Heart Institute (InCor), University of São Paulo Medical School Hospital, São Paulo, Brazil. Electronic address: raul.santos@incor.usp.br.
Abstract
BACKGROUND: Dietary habits play an important role in the development of atherosclerosis, the most important cause of morbidity and mortality in the world. The objective of this study was to verify if vegetarian (VEG) diet could be related a better profile of subclinical vascular disease evaluated by arterial stiffness and functional and structural properties of carotid arteries, compared to omnivorous (OMN) diet. METHODS: In this cross-sectional study, 44 VEG and 44 OMN apparently healthy men ≥35years of age, in order to not have confounding risk factors of subclinical atherosclerosis, were assessed for anthropometric data, blood pressure, blood lipids, glucose, C reactive protein (CRP), and arterial stiffness determined by carotid-femoral pulse wave velocity (PWV). Also, carotid intima-media thickness (c-IMT) and distensibility were evaluated. RESULTS: VEG men had lower body mass index, systolic and diastolic blood pressures, fasting serum total cholesterol, LDL and non-HDL-cholesterol, apolipoprotein B, glucose and glycated hemoglobin values in comparison with OMN individuals (all p values <0.05). Markers of vascular structure and function were different between VEG and OMN: PWV 7.1±0.8m/s vs. 7.7±0.9m/s (p<0.001); c-IMT 593±94 vs. 661±128μm (p=0.003); and relative carotid distensibility 6.39±1.7 vs. 5.72±1.8% (p=0.042), respectively. After a multivariate linear regression analysis, a VEG diet was independently and negatively associated with PWV (p value 0.005). CONCLUSIONS: A VEG diet is associated with a more favorable cardiovascular diseases biomarker profile and better vascular structural and functional parameters.
BACKGROUND: Dietary habits play an important role in the development of atherosclerosis, the most important cause of morbidity and mortality in the world. The objective of this study was to verify if vegetarian (VEG) diet could be related a better profile of subclinical vascular disease evaluated by arterial stiffness and functional and structural properties of carotid arteries, compared to omnivorous (OMN) diet. METHODS: In this cross-sectional study, 44 VEG and 44 OMN apparently healthy men ≥35years of age, in order to not have confounding risk factors of subclinical atherosclerosis, were assessed for anthropometric data, blood pressure, blood lipids, glucose, C reactive protein (CRP), and arterial stiffness determined by carotid-femoral pulse wave velocity (PWV). Also, carotid intima-media thickness (c-IMT) and distensibility were evaluated. RESULTS: VEG men had lower body mass index, systolic and diastolic blood pressures, fasting serum total cholesterol, LDL and non-HDL-cholesterol, apolipoprotein B, glucose and glycated hemoglobin values in comparison with OMN individuals (all p values <0.05). Markers of vascular structure and function were different between VEG and OMN: PWV 7.1±0.8m/s vs. 7.7±0.9m/s (p<0.001); c-IMT 593±94 vs. 661±128μm (p=0.003); and relative carotid distensibility 6.39±1.7 vs. 5.72±1.8% (p=0.042), respectively. After a multivariate linear regression analysis, a VEG diet was independently and negatively associated with PWV (p value 0.005). CONCLUSIONS: A VEG diet is associated with a more favorable cardiovascular diseases biomarker profile and better vascular structural and functional parameters.
Authors: Richard M Rosenfeld; John H Kelly; Monica Agarwal; Karen Aspry; Ted Barnett; Brenda C Davis; Denise Fields; Trudy Gaillard; Mahima Gulati; George E Guthrie; Denee J Moore; Gunadhar Panigrahi; Amy Rothberg; Deepa V Sannidhi; Lorraine Weatherspoon; Kaitlyn Pauly; Micaela C Karlsen Journal: Am J Lifestyle Med Date: 2022-05-18
Authors: Julio Cesar Acosta Navarro; Luiza Antoniazzi; Adriana Midori Oki; Maria Carlos Bonfim; Valeria Hong; Luiz Aparecido Bortolotto; Pedro Acosta-Cardenas; Valeria Sandrim; Marcio Hiroshi Miname; Raul Dias Dos Santos Filho Journal: Arq Bras Cardiol Date: 2018-05 Impact factor: 2.000