Literature DB >> 28039578

The Importance of Standardization on Analyzing Circulating RNA.

Inyoul Lee1, David Baxter1, Min Young Lee1, Kelsey Scherler1, Kai Wang2.   

Abstract

Circulating RNAs, especially microRNAs (miRNAs), have recently emerged as non-invasive disease biomarkers. Despite enthusiasm and numerous reports on disease-associated circulating miRNAs, currently there is no circulating miRNA-based diagnostic in use. In addition, there are many contradictory reports on the concentration changes of specific miRNA in circulation. Here we review the impact of various technical and non-technical factors related to circulating miRNA measurement and elucidate the importance of having a general guideline for sample preparation and concentration measurement in studying circulating RNA.

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Year:  2017        PMID： 28039578      PMCID： PMC5426982          DOI： 10.1007/s40291-016-0251-y

Source DB:  PubMed          Journal:  Mol Diagn Ther        ISSN： 1177-1062            Impact factor:   4.074


  114 in total

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Journal:  Cell       Date:  2008-01-11       Impact factor: 41.582

4.  Global correlation analysis for micro-RNA and mRNA expression profiles in human cell lines.

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5.  Deep learning of support vector machines with class probability output networks.

Authors:  Sangwook Kim; Zhibin Yu; Rhee Man Kil; Minho Lee
Journal:  Neural Netw       Date:  2014-10-07

6.  Cardiac-specific troponin I levels to predict the risk of mortality in patients with acute coronary syndromes.

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7.  MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins.

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8.  Expression and rhythmic modulation of circulating microRNAs targeting the clock gene Bmal1 in mice.

Authors:  Vikram R Shende; Marianna M Goldrick; Suchitra Ramani; David J Earnest
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9.  Real-time quantification of microRNAs by stem-loop RT-PCR.

Authors:  Caifu Chen; Dana A Ridzon; Adam J Broomer; Zhaohui Zhou; Danny H Lee; Julie T Nguyen; Maura Barbisin; Nan Lan Xu; Vikram R Mahuvakar; Mark R Andersen; Kai Qin Lao; Kenneth J Livak; Karl J Guegler
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Journal:  PLoS One       Date:  2014-02-19       Impact factor: 3.240
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1.  Molecular Med TRI-CON, 11-16 February 2018, San Francisco, USA.

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Journal:  Mol Diagn Ther       Date:  2018-04       Impact factor: 4.074

Review 2.  Circulating non-coding RNAs as a diagnostic and management biomarker for breast cancer: current insights.

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3.  Identification of Stably Expressed Reference microRNAs in Epithelial Ovarian Cancer.

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Journal:  In Vivo       Date:  2022 May-Jun       Impact factor: 2.406

4.  Analytical Validation and Performance Characteristics of Molecular Serum Biomarkers, miR-371a-3p and miR-372-3p, for Male Germ Cell Tumors, in a Clinical Laboratory Setting.

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6.  A comprehensive characterization of the cell-free transcriptome reveals tissue- and subtype-specific biomarkers for cancer detection.

Authors:  Matthew H Larson; Wenying Pan; Hyunsung John Kim; Ruth E Mauntz; Sarah M Stuart; Monica Pimentel; Yiqi Zhou; Per Knudsgaard; Vasiliki Demas; Alexander M Aravanis; Arash Jamshidi
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7.  Genome-wide Profiling of Urinary Extracellular Vesicle microRNAs Associated With Diabetic Nephropathy in Type 1 Diabetes.

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Review 9.  Epigenetics, microRNA and Metabolic Syndrome: A Comprehensive Review.

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10.  Droplet digital polymerase chain reaction-based quantification of circulating microRNAs using small RNA concentration normalization.

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