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Literature DB >> 27984855

Anion Recognition as a Supramolecular Switch of Cell Internalization.

Jéssica Rodríguez¹, Jesús Mosquera^1,2, José R Couceiro¹, Jonathan R Nitschke², M Eugenio Vázquez¹, José L Mascareñas².

Abstract

The cell internalization of designed oligoarginine peptides equipped with six glutamic acid residues and an anionic pyranine at the N-terminus is triggered upon addition of a supramolecular host. This host binds specifically to the pyranine moiety, enabling the complex to traverse the cell membrane. Interestingly, none of the components, neither the host nor the guest, are able to cross the cell membrane on their own.

Entities: Chemical

Mesh：

Substances：

Year: 2016 PMID： 27984855 PMCID： PMC5389450 DOI： 10.1021/jacs.6b11103

Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419

52 in total

1. Design and Synthesis of a Peptide That Binds Specific DNA Sequences through Simultaneous Interaction in the Major and in the Minor Groove This work was supported by the Spanish M.E.C. (PB97-0524) and the Xunta de Galicia (PGIDT00PXI20912PR). M.E.V. and A.M.C. thank the Xunta de Galicia and the University of Santiago for their predoctoral fellowships. We are very grateful to Prof. G. L. Verdine for his input and support in the early phases of this work. We also thank Prof. J. Benavente for allowing us to use the radioactivity facilities and Prof. C. Abell for critical reading of the manuscript.

Authors: M. Eugenio Vázquez; Ana M. Caamaño; José Martínez-Costas; Luis Castedo; José L. Mascareñas
Journal: Angew Chem Int Ed Engl Date: 2001-12-17 Impact factor: 15.336

2. A 3D interlocked structure from a 2D template: structural requirements for the assembly of a square-planar metal-coordinated [2]rotaxane.

Authors: Anne-Marie Fuller; David A Leigh; Paul J Lusby; Iain D H Oswald; Simon Parsons; D Barney Walker
Journal: Angew Chem Int Ed Engl Date: 2004-07-26 Impact factor: 15.336

3. Direct and rapid cytosolic delivery using cell-penetrating peptides mediated by pyrenebutyrate.

Authors: Toshihide Takeuchi; Michie Kosuge; Akiko Tadokoro; Yukio Sugiura; Mayumi Nishi; Mitsuhiro Kawata; Naomi Sakai; Stefan Matile; Shiroh Futaki
Journal: ACS Chem Biol Date: 2006-06-20 Impact factor: 5.100

Review 4. Methodological and cellular aspects that govern the internalization mechanisms of arginine-rich cell-penetrating peptides.

Authors: Ikuhiko Nakase; Toshihide Takeuchi; Gen Tanaka; Shiroh Futaki
Journal: Adv Drug Deliv Rev Date: 2007-10-22 Impact factor: 15.470

Review 5. Cell penetrating peptides: intracellular pathways and pharmaceutical perspectives.

Authors: Leena N Patel; Jennica L Zaro; Wei-Chiang Shen
Journal: Pharm Res Date: 2007-04-19 Impact factor: 4.200

6. Possible existence of common internalization mechanisms among arginine-rich peptides.

Authors: Tomoki Suzuki; Shiroh Futaki; Miki Niwa; Seigo Tanaka; Kunihiro Ueda; Yukio Sugiura
Journal: J Biol Chem Date: 2001-11-15 Impact factor: 5.157

7. Tumor imaging by means of proteolytic activation of cell-penetrating peptides.

Authors: Tao Jiang; Emilia S Olson; Quyen T Nguyen; Melinda Roy; Patricia A Jennings; Roger Y Tsien
Journal: Proc Natl Acad Sci U S A Date: 2004-12-15 Impact factor: 11.205

8. Intracellular cargo delivery by an octaarginine transporter adapted to target prostate cancer cells through cell surface protease activation.

Authors: Elena A Goun; Rajesh Shinde; Karen W Dehnert; Angie Adams-Bond; Paul A Wender; Christopher H Contag; Benjamin L Franc
Journal: Bioconjug Chem Date: 2006 May-Jun Impact factor: 4.774

9. Solid-phase peptide synthesis: from standard procedures to the synthesis of difficult sequences.

Authors: Irene Coin; Michael Beyermann; Michael Bienert
Journal: Nat Protoc Date: 2007 Impact factor: 13.491

10. Overcoming multidrug resistance of small-molecule therapeutics through conjugation with releasable octaarginine transporters.

Authors: Elena A Dubikovskaya; Steve H Thorne; Thomas H Pillow; Christopher H Contag; Paul A Wender
Journal: Proc Natl Acad Sci U S A Date: 2008-08-19 Impact factor: 11.205

11 in total

1. Cucurbit[7]uril Enables Multi-Stimuli-Responsive Release from the Self-Assembled Hydrophobic Phase of a Metal Organic Polyhedron.

Authors: Soumen K Samanta; Jeffrey Quigley; Brittany Vinciguerra; Volker Briken; Lyle Isaacs
Journal: J Am Chem Soc Date: 2017-06-23 Impact factor: 15.419

10. A Two-Dimensional Metallacycle Cross-Linked Switchable Polymer for Fast and Highly Efficient Phosphorylated Peptide Enrichment.

Authors: Li-Jun Chen; Sean J Humphrey; Jun-Long Zhu; Fan-Fan Zhu; Xu-Qing Wang; Xiang Wang; Jin Wen; Hai-Bo Yang; Philip A Gale
Journal: J Am Chem Soc Date: 2021-05-27 Impact factor: 15.419

Anion Recognition as a Supramolecular Switch of Cell Internalization.

2. A 3D interlocked structure from a 2D template: structural requirements for the assembly of a square-planar metal-coordinated [2]rotaxane.

3. Direct and rapid cytosolic delivery using cell-penetrating peptides mediated by pyrenebutyrate.

Review 4. Methodological and cellular aspects that govern the internalization mechanisms of arginine-rich cell-penetrating peptides.

Review 5. Cell penetrating peptides: intracellular pathways and pharmaceutical perspectives.

6. Possible existence of common internalization mechanisms among arginine-rich peptides.

7. Tumor imaging by means of proteolytic activation of cell-penetrating peptides.

8. Intracellular cargo delivery by an octaarginine transporter adapted to target prostate cancer cells through cell surface protease activation.

9. Solid-phase peptide synthesis: from standard procedures to the synthesis of difficult sequences.

10. Overcoming multidrug resistance of small-molecule therapeutics through conjugation with releasable octaarginine transporters.

1. Cucurbit[7]uril Enables Multi-Stimuli-Responsive Release from the Self-Assembled Hydrophobic Phase of a Metal Organic Polyhedron.

2. Modular Metal-Organic Polyhedra Superassembly: From Molecular-Level Design to Targeted Drug Delivery.

3. Efficient Delivery of Quantum Dots into the Cytosol of Cells Using Cell-Penetrating Poly(disulfide)s.

4. Excitation Energy Delocalization and Transfer to Guests within M^II₄L₆ Cage Frameworks.

5. Reversible Control of Protein Corona Formation on Gold Nanoparticles Using Host-Guest Interactions.

6. Self Assembled Cages with Mechanically Interlocked Cucurbiturils.

7. Metal-Dependent DNA Recognition and Cell Internalization of Designed, Basic Peptides.

Review 8. Cell-Penetrating Peptides: Design Strategies beyond Primary Structure and Amphipathicity.

9. Supramolecular caging for cytosolic delivery of anionic probes.

10. A Two-Dimensional Metallacycle Cross-Linked Switchable Polymer for Fast and Highly Efficient Phosphorylated Peptide Enrichment.