Literature DB >> 27977900

Noneligible Donors as a Strategy to Decrease the Organ Shortage.

K P Croome1, D D Lee1, A P Keaveny1, C B Taner1.   

Abstract

Organ procurement organization (OPO) performance is generally evaluated by the number of organ procurement procedures divided by the number of eligible deaths (donation after brain death [DBD] donors aged <70 years), whereas the number of noneligible deaths (including donation after cardiac death donors and DBD donors aged >70 years) is not tracked. The present study aimed to investigate the variability in the proportion of noneligible liver donors by the 58 donor service areas (DSAs). Patients undergoing liver transplant (LT) between 2011 and 2015 were obtained from the United Network for Organ Sharing Standard Transplant Analysis and Research file. LTs from noneligible and eligible donors were compared. The proportion of noneligible liver donors by DSA varied significantly, ranging from 0% to 19.6% of total liver grafts used. In transplant programs, the proportion of noneligible liver donors used ranged from 0% to 35.3%. On linear regression there was no correlation between match Model for End-Stage Liver Disease score for programs in a given DSA and proportion of noneligible donors used from the corresponding DSA (p = 0.14). Noneligible donors remain an underutilized resource in many OPOs. Policy changes to begin tracking noneligible donors and learning from OPOs that have high noneligible donor usage are potential strategies to increase awareness and pursuit of these organs.
© 2016 The American Society of Transplantation and the American Society of Transplant Surgeons.

Entities:  

Keywords:  clinical research/practice; donors and donation: donation after circulatory death (DCD); donors and donation: extended criteria; health services and outcomes research; liver transplantation/hepatology; organ procurement and allocation

Mesh:

Year:  2017        PMID: 27977900     DOI: 10.1111/ajt.14163

Source DB:  PubMed          Journal:  Am J Transplant        ISSN: 1600-6135            Impact factor:   8.086


  12 in total

1.  Offer acceptance practices and geographic variability in allocation model for end-stage liver disease at transplant.

Authors:  Andrew Wey; Joshua Pyke; David P Schladt; Sommer E Gentry; Tim Weaver; Nicholas Salkowski; Bertram L Kasiske; Ajay K Israni; Jon J Snyder
Journal:  Liver Transpl       Date:  2018-04       Impact factor: 5.799

2.  Outcomes of Donation After Circulatory Death Liver Grafts From Donors 50 Years or Older: A Multicenter Analysis.

Authors:  Kristopher P Croome; Amit K Mathur; David D Lee; Adyr A Moss; Charles B Rosen; Julie K Heimbach; C Burcin Taner
Journal:  Transplantation       Date:  2018-07       Impact factor: 4.939

3.  Heart and lung organ offer acceptance practices of transplant programs are associated with waitlist mortality and organ yield.

Authors:  Andrew Wey; Maryam Valapour; Melissa A Skeans; Nicholas Salkowski; Monica Colvin; Bertram L Kasiske; Ajay K Israni; Jon J Snyder
Journal:  Am J Transplant       Date:  2018-05-09       Impact factor: 8.086

4.  Minimizing Risk Associated With Older Liver Donors by Matching to Preferred Recipients: A National Registry and Validation Study.

Authors:  Christine E Haugen; Alvin G Thomas; Jacqueline Garonzik-Wang; Allan B Massie; Dorry L Segev
Journal:  Transplantation       Date:  2018-09       Impact factor: 4.939

5.  Wide variation in the percentage of donation after circulatory death donors across donor service areas - a potential target for improvement.

Authors:  Elizabeth M Sonnenberg; Jesse Y Hsu; Peter P Reese; David Goldberg; Peter L Abt
Journal:  Transplantation       Date:  2019-10-21       Impact factor: 4.939

6.  Survival benefit of accepting livers from deceased donors over 70 years old.

Authors:  Christine E Haugen; Mary G Bowring; Courtenay M Holscher; Kyle R Jackson; Jacqueline Garonzik-Wang; Andrew M Cameron; Benjamin Philosophe; Mara McAdams-DeMarco; Dorry L Segev
Journal:  Am J Transplant       Date:  2019-01-25       Impact factor: 8.086

7.  Assessment of Trends in Transplantation of Liver Grafts From Older Donors and Outcomes in Recipients of Liver Grafts From Older Donors, 2003-2016.

Authors:  Christine E Haugen; Courtenay M Holscher; Xun Luo; Mary Grace Bowring; Babak J Orandi; Alvin G Thomas; Jacqueline Garonzik-Wang; Allan B Massie; Benjamin Philosophe; Mara McAdams-DeMarco; Dorry L Segev
Journal:  JAMA Surg       Date:  2019-05-01       Impact factor: 14.766

8.  Evaluating Spatial Associations in Inpatient Deaths Between Organ Procurement Organizations.

Authors:  Joel T Adler; Tanujit Dey
Journal:  Transplant Direct       Date:  2021-02-11

9.  Aggressive pursuit and utilization of non-ideal donor lungs does not compromise post-lung transplant survival.

Authors:  Samantha E Halpern; Oliver K Jawitz; Vignesh Raman; Ashley Y Choi; John C Haney; Jacob A Klapper; Matthew G Hartwig
Journal:  Clin Transplant       Date:  2021-07-14       Impact factor: 3.456

10.  Wide Variation in the Percentage of Donation After Circulatory Death Donors Across Donor Service Areas: A Potential Target for Improvement.

Authors:  Elizabeth M Sonnenberg; Jesse Y Hsu; Peter P Reese; David S Goldberg; Peter L Abt
Journal:  Transplantation       Date:  2020-08       Impact factor: 5.385

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