OBJECTIVE: To assess iodine status among pregnant women in rural Zinder, Niger and to compare their status with the iodine status of school-aged children from the same households. DESIGN: Seventy-three villages in the catchment area of sixteen health centres were randomly selected to participate in the cross-sectional survey. SETTING: Salt iodization is mandatory in Niger, requiring 20-60 ppm iodine at the retail level. SUBJECTS: A spot urine sample was collected from randomly selected pregnant women (n 662) and one school-aged child from the same household (n 373). Urinary iodine concentration (UIC) was assessed as an indicator of iodine status in both groups. Dried blood spots (DBS) were collected from venous blood samples of pregnant women and thyroglobulin (Tg), thyroid-stimulating hormone and total thyroxine were measured. Iodine content of household salt samples (n 108) was assessed by titration. RESULTS: Median iodine content of salt samples was 5·5 ppm (range 0-41 ppm), 98 % had an iodine content 40 µg/l. CONCLUSIONS: In this region of Niger, most salt is inadequately iodized. UIC in pregnant women indicated iodine deficiency, whereas UIC of school-aged children indicated marginally adequate iodine status. Thus, estimating population iodine status based solely on monitoring of UIC among school-aged children may underestimate the risk of iodine deficiency in pregnant women.
OBJECTIVE: To assess iodine status among pregnant women in rural Zinder, Niger and to compare their status with the iodine status of school-aged children from the same households. DESIGN: Seventy-three villages in the catchment area of sixteen health centres were randomly selected to participate in the cross-sectional survey. SETTING:Salt iodization is mandatory in Niger, requiring 20-60 ppm iodine at the retail level. SUBJECTS: A spot urine sample was collected from randomly selected pregnant women (n 662) and one school-aged child from the same household (n 373). Urinary iodine concentration (UIC) was assessed as an indicator of iodine status in both groups. Dried blood spots (DBS) were collected from venous blood samples of pregnant women and thyroglobulin (Tg), thyroid-stimulating hormone and total thyroxine were measured. Iodine content of household salt samples (n 108) was assessed by titration. RESULTS: Median iodine content of salt samples was 5·5 ppm (range 0-41 ppm), 98 % had an iodine content 40 µg/l. CONCLUSIONS: In this region of Niger, most salt is inadequately iodized. UIC in pregnant women indicated iodine deficiency, whereas UIC of school-aged children indicated marginally adequate iodine status. Thus, estimating population iodine status based solely on monitoring of UIC among school-aged children may underestimate the risk of iodine deficiency in pregnant women.
Authors: Sonja Y Hess; Césaire T Ouédraogo; Ibrahim F Bamba; K Ryan Wessells; Nancy Keith; Thierno Faye; Banda Ndiaye; Maimouna Doudou; Jennifer Nielsen Journal: Matern Child Nutr Date: 2017-09-19 Impact factor: 3.092
Authors: Erika S O Patriota; Isis C C Lima; Eduardo A F Nilson; Sylvia C C Franceschini; Vivian S S Gonçalves; Nathalia Pizato Journal: Eur J Clin Nutr Date: 2021-09-20 Impact factor: 4.884
Authors: K Ryan Wessells; Césaire T Ouédraogo; Rebecca R Young; M Thierno Faye; Alex Brito; Sonja Y Hess Journal: Nutrients Date: 2017-04-26 Impact factor: 5.717
Authors: Joana L A Miranda; Raquel B R Mesquita; Edwin Palacio; José M Estela; Víctor Cerdà; António O S S Rangel Journal: Molecules Date: 2022-02-16 Impact factor: 4.411
Authors: Eleanor Brindle; Lorraine Lillis; Rebecca Barney; Sonja Y Hess; K Ryan Wessells; Césaire T Ouédraogo; Sara Stinca; Michael Kalnoky; Roger Peck; Abby Tyler; Christopher Lyman; David S Boyle Journal: PLoS One Date: 2017-10-05 Impact factor: 3.240
Authors: Cesaire T Ouedraogo; K Ryan Wessells; Rebecca R Young; Ibrahim Foungotin Bamba; M Thierno Faye; Ndiaye Banda; Sonja Y Hess Journal: BMJ Glob Health Date: 2019-12-10